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18 Cards in this Set

  • Front
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enzyme steps

1. citrate synthase


2. aconitase


3. isocitrate dehydrogenase


4. alpha-KG dehydrogenase complex


5. succinyl-CoA synthetase


6. succinate dehydrogenase


7.fumarase


8 malate dehydrogenase

citrate synthase

oxaloacetae + acetylCoA --> citrate



-1 H2O

aconitase

citrate --> isocitrate

isocitrate dehydrogenase

isocitrate --> alpha-KG + CO2



+1 NADH

alpha-ketoglutarate dehydrogenase complex

alpha-KG + CoASH --> succinylCoA + CO2



+1 NADH

succinyl-CoA synthetase

succinylCoA ---> succinate + CoA-SH



+1 GTP

succinate dehydrogenase

succinate --> fumarate



+1 FADH2

fumarase

fumarate --> L-malate



-1 H2O

malate dehydrogenase

malate --> oxaloacetate



+1 NADH

oxaloacetate

citrate

isocitrate

alpha-ketoglutarate

succinylCoA

succinate

fumarate

malate

Kreb's cycle

OAA + acetyl CoA


-> citrate (- 1H2O)


-> isocitrate


-> alphaKG (+ 1 NADH)


-> succinylCoA (+ 1 NADH)


-> succinate (+ 1 GTP)


-> fumarate (+1 FADH2)


-> malate (- 1 H2O)


-> OAA (+1 NADH)