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136 Cards in this Set

  • Front
  • Back
Mendel concluded that each pea has___ for each trait, and each gamete contains___.
two units, one unit
Although he did not realize it, Mendel concluded that each pea units for each trait. Mendel's "units" are now referred to as___, and with his law of segregation he discovered___.
genes, equational division
Peas were a good organism of choice for Mendel because?
he could study one trait at a time
The region of the chromosome occupied by a gene is called a locus. T/F?
True
Recessive characteristics like hemophilia occur on the___, and therefore show up___.
"x" chromosome, more often in males
Mendel's paper on inheritance did not include:
principle of unit isolation
A recessive gene is one___?
whose effect is masked by a dominant allele
Which of the following statements is false?
matings between individuals with dominant phenotypes cannot produce offspring with recessive phenotypes
If, in a heterozygous individual, only one allele is expressed in the phenotype, that allele is___?
Dominant
The physical manifestation of an organism's genes is its___?
phenotype
A cross produced 915 offspring with normal pigment and 310 with albinism. Conclusion?
both parents were heterozygous
If we cross two pea plants each heterozygous for yellow seed color genes, the expected ratio of yellow: green among the offspring will be___?
100% yellow
What type of allele produces its effects only in homozygous individuals?
recessive
When two alleles of a gene move into different gametes, this demonstrates?
segregation
Genetic information flows from:
genes--->mRNA--->protein--->phenotype
Mendel's law of Segregation states that?
members of a pair of alleles move away from each other during gamete formation
When Mendel used true-breeding white flowers and true-breeding purple flowers as the parental generation, he obtained which of the following results?
all the offspring had purple flowers
The results of a test cross reveal that all the offspring resemble the parent being tested. This parent must be?
homozygous
A Mendelian test cross is used to determine whether___?
an individual is homozygous or heterozygous
Considering only independent assortment of chromosomes, an animal with 20 pairs of chromosomes could make___ different sex cells.
2^20
To make the genotype of an individual, it must be test crossed with a ___.
homozygous recessive individual
The physical expression of characteristics are referred to as ___, while the genetic makeup is referred to as ___.
phenotype, genotype
What is the genotype of a dominant individual if some of its offspring show the recessive phenotype?
Dd
Many different genotypes intermediate to their parents, like intelligence and height, would most likely be controlled by ___?
multiple gene effects
A mono-hybrid cross will usually result in ___ phenotypes and ___ genotypes if both parents are heterozygous.
2,3
Classical albinism results from a recessive allele. Which of the following is the expected offspring from a normally pigmented male with an albino father and albino wife?
50% normal, 50% albino
If two parents are carriers of albinism (an autosomal recessive trait), what is the chance that their fourth child will have a homozygous genotype?
50%
A mutation in the DNA occurs such that adenine is substituted by guanine. This would be called a ___ mutation.
point
A gene that has many different copies in a chromosome would be an example of ___, while a loss of a gene would be an example of ___.
duplication, deletion
Because alleles have been selected for over long periods of time which of the following is the most correct statement about mutations?
about one in a thousand beneficial
The independent inheritance of two or more distinct traits is called segregation. T/F?
False
What is a physical requirement in order for independent assortment of alleles for two different genes to occur?
genes must be on different chromosomes
Where in cell division does the actual process of independent assortment of alleles occur?
metaphase I
Homologous pairs of synapsed chromosomes align randomly along the metaphase plate during ____?
metaphase II
When two loci are on the same chromosome the phenotypes of the progeny sometimes do not follow the law of independent assortment because they are ___?
linkage
Which of the following is true of genes that are found near each other on the same chromosome?
-they tend to be inherited together
-they are linked
When genes are linked, the reason that a few recombinant genotypes still occur in the offspring is because of ____?
crossing over
Evolution is best understood by changes in gene/allele frequencies of ___?
populations
What would be true if linkage of two genes were complete (very close together)?
Crossing over between the two genes would never occur
Humans possess ___?
1 pair of sex chromosomes and 22 pairs of autosomes
A human sperm cell receives autosomes and ___?
either an X or a Y chromosome
In humans, the sex of the offspring is determined by the ___?
sex chromosome carried by the sperm cell
A female fruit fly whose male parent has white eyes ___?
must have a gene for white eyes
A, B, & O characters would be an example of ___?
multiple allele characters
Traits controlled by sex-linked recessive genes are expressed more often in males because ___?
the male has only one gene for the trait
A recessive allele on the X chromosome causes colorblindness. A non-colorblind woman (whose father is colorblind) marries a colorblind man. What is the chance their son will be colorblind?
50%
Hemophilia is a sex-linked recessive gene causing a blood disorder. What are the chances that the daughter of a normal man and a heterozygous woman will have hemophilia?
0% chance
(50% if a boy)
All of the characters that Mendel chose were ___ , ___, and ___.
dominant, recessive, not linked
If two plants are crossed, one white flowered and the other red flowered, and some of the F1 flowers were pink, this is an example of ___?
codominance
Color blindness is more common in men than in women because ___?
men have only one X chromosome
Why would you predict that half of the human babies born will be males and half will be females?
-because of the segregation of the X and Y chromosomes during male meiosis
-because all eggs contain an X chromosome
An individual who is a "carrier" for a sex-linked trait like hemophilia ___.
-is always female
-is heterozygous for recessive condition
-shows the dominant phenotype
-can pass the gene on to his/her daughters
Hemophilia is a genetic disease that has plagued the royal houses of Europe since the time of Queen Victoria, who was a carrier. How had the Queen become a carrier since there had never been hemophilia in her background?
an allele mutated in a gamete forming her
A type of muscular dystrophy show sex-linked recessive inheritance. Affected persons usually die by the age of 15-20. Suppose that a boy with the disease lives long enough to marry a woman heterozygous for the trait. If they have a son, what is the probability that he will have the disease?
50%
Mendel discovered reduction division when he discovered the Principle of ____.
segregation
Only males can express sex-linked traits.T/F?
false
Males always inherit sex-linked traits from their fathers. T/F?
false
Sex-linked traits affect only sexual characteristics.T/F?
false
In humans there are 22 pairs of ____ and one pair of ____.
autosomes, sex chromosomes
Blood typing is often used as evidence in paternity cases in court. In one case, the mother had blood type B and the child had blood type O. Which of the following blood types could the father NOT have?
AB
In Mendel's experiments, if the gene for tall (T) plants was incompletely dominant over the gene for short (t) plants, what would be the result of crossing two Tt plants?
25% tall; 50% intermediate; 25% short
The intense selection for average sized snake eggs is an example of ____ selection.
stabilizing
Nondysjunction of chromosomes occurs in all species but has little effect except with the ___.
autosomes
A genetic disease due to the lack of clotting factor is ___?
Hemophilia
Human skin color is the result of ___?
polygenic inheritance
If an individual who is homozygous for type B blood marries a heterozygous type A individual, what is the chance that their first child will have type AB blood?
50%
Studies show the greatest similarity on IQ test scores is between ___?
identical twins raised in the same environment
In snapdragons, heterozygotes have pink flowers, and the two homozygous individuals are red or white. When a red flowered plant is crossed with a white flowered plant, what proportion of the offspring will have pink flowers?
100%
In human blood types the alleles for A and B are said to be ___ because they are both expressed.
co-dominant
The blood types of humans are an example of ___?
multiple alleles
The resulting pink flowers which occur after crossing red and white snapdragons is most likely a result of ___.
incomplete dominance
Human females who receive sex-linked genes always express them. T/F?
false
A female who is heterozygous for a recessive, sex-linked character is a carrier for that character. T/F?
true
Klinefelter syndrome is ___.
sex chromosomal nondisjunction
A sex-linked recessive condition resulting in abnormally excessive bleeding is ___?
hemophilia
A disorder caused by non-disjunction of chromosome 21 resulting in a trisomy 21 child is___?
down syndrome
A sex-linked recessive condition causing abnormal color vision is called ___?
red-green colorblindness
The failure of chromosomes to segregate properly during meiosis is called___?
nondisjunction
Which disorder is characterized by short females with webbed necks, being less fertile, and sometimes lower intelligence?
turner syndrome
Which disorder is characterized by the individual having a abnormal number of sex chromosomes?
down syndrome
Which disorder is characterized by an abnormal number of autosomes?
down syndrome
Among mothers over 40 years old, which disorder is the most common chromosome abnormality among newborns?
down syndrome
Red-green colorblindness is ____.
sex-linked recessive
Sickle-cell anemia is caused by____?
recessive autosomal in all cells
Turner syndrome is ____?
sex chromosomal nondisjunction of the "X" chromosome
One of the best examples of artificial selection would be found in ___.
dogs
Dogs, coyotes, and wolves are isolated from one another by ____ isolation, while horses and donkeys are isolated by____.
behavioral, genetic
If two different alleles are present in the organism, it is referred to as being ___?
heterozygous
Populations that usually grow exponentially are usually limited by ___.
-food
-predators
-disease
-shortage of space
For severe selection to occur environmental resources must become limiting. T/F?
true
During a storm a small flock of sparrows were driven out to sea. The establishment of a new population of birds on an island where none had previously existed is an example of ____.
founder's effect
The migration of Spanish alleles in the Indian population would have had a ____ genetic effect on the native population?
little
When a few individuals of a species survive a natural catastrophe such as a fire by chance or luck, change in allelic frequencies in surviving population is referred to as
evolutionary bottleneck
The horse and camel arose in ____, while the elephant arose in ____.
north america, asia
Vestigial characters, like the appendix or poorly formed hindlimbs on some snakes, are characters that were in ones ancestors but have now lost their function. T/F?
true
The corn, squash, tomatoes, and many peppers arose in ____, while the wheat arose in ____.
north america, south america
Klinefelder's or Turner's syndrome are examples of ___.
aneupolyploids
The Irish population exploded during 1840's because of the introduction to the ____ and crashed because of ____.
potato, potato fungus
Mallard and Pintail ducks are examples of true species that are reproductively isolated by
behavioral isolation
Genetic differences arise and bring about new species which no longer breed with each other because gene frequencies in populations change over time under the influence of ____.
genetic drift
Historically, genetic disorders have been treated by addressing the biological events that result from the genetic mutation, but now the disorder is treated by inserting or integrating new genes into human cell. T/F?
true
Two broad categories therapy would include___?
-germ line gene therapy
-somatic cell gene therapy
The alteration of non-reproductive body cells would be called___?
somatic cell gene therapy
The resulting genetic changes will be passed on to the patient's offspring only in___?
germ-line gene therapy
A vector is simply a "transporter" for the genetic material that allows it to enter the target cell. T/F?
true
Which of the following would not be used as a vector?
proteins
Which of the following allows the vector to penetrate the cell?
protein outer protective viral coat
The type of cell that a given virus will infect is determined by the
protein outer protective viral coat
When scientists retain the outer viral coat, but modify the inner genetic material which of the following is true?
-they remove the harmful genes and replace them with therapeutic ones
-now the virus is pathogenically disabled and incapable of reproducing itself
- it retains its capability to transfer its genetic material to the cells for which its outer coat
The transfer of genetic material by way of a viral vector is called___?
transduction
Retroviruses tend___.
-not to be very harmful to the cell
-are safer than viral vectors that are deactivated
-most retroviruses target actively dividing cells
-are ideal for the treatment of rapidly dividing tumor cells
The correct order of events for introducing genetic info into a tumor cell would be___?
5,6,1,2,3,4,
5) virus particles containing a novel gene are incubated with mouse cells in a dish, 6)the virus particles infect the mouse cells, 1)the mouse cells become virus producer cells, 2)producer cells are injected directly into the tumor, 3)viruses released by producer cells invade rapidly-dividing tumor cells but ignore surrounding brain cells, 4)virus particles cause infected tumor and producer cells to construct a protein that makes them vulnerable to destruction
Adenoviral vectors send their DNA to the nucleus, but the DNA does not get incorporated into the host cell's chromosomes. T/F?
true
Because the viral adenovirus RNA has a finite lifetime within the cell before it is degraded, the added genes are effective only temporarily treatments needs to be repeated periodically. T/F?
true
Small, hollow spheres of fatty molecules that are capable of carrying DNA inside of them and can fuse with the cell membrane, releasing its contents into the cell interior are called____?
liposomes
Principal ways in which vectors can be administered to carry new genes into target cells___?
-ex vivo somatic gene
-in situ gene therapy
-ex vivo somatic gene
The technique used in cloning Dolly, and also possibly cloning a mammoth, is called a nuclear transfer technology. T/F?
true
The correct order of events for introducing genetic info from one kind of sheep into a different kind of sheep would be____?
5,6,1,2,3,4
5)epithelial cells are plucked from the udder of a white faced ewe 6)an egg from the same species, black faced ewe, is removed and its nucleus removed, 1)the udder cell and empty egg are placed together and fused, 2)this combines the nucleus and egg cytoplasm together,3) then the blastula is implanted into the uterus of a blackface ewe 4)the result of this is a duplicate of the donor organism
Because the recipient egg has MRNA and many organelles in its cytoplasm unfamiliar to teh introduced nucleus, the clone may be slightly different from the donor. T/F?
true
The two little miracles were caused by___.
random combinations of sex cells
Like other scientists of their time, Alfred Wallace and Charles Darwin did not understand which of the following?
inheritance
As the Romantic Period of thought died, the Agnostic Period arose. About what year was this?
1905
Which one of the following scientist did not re-discover the scientific paper on genetics by Mendel?
Hutton
Who proposed concept of natural selection, didn't understand genetics, and proposed his own theory of pangenesis?
Darwin
Who, from his many observations realized that species change over time and also with geographical distance, rejected view species were created and remain unchanged, realized importance of artificial selection, but didn't see how it worked until he read Malthus' essay (1799) in 1838.
Darwin
Which of the following had an influence on Charles Darwin?
-knowledge of biogeography
-Fossil Record and Comparative Anatomy
-Uniformitarianism
-Malthus' Essay on populations and breeding of domesticated animals-pigeons
Basically the current view and the concept published in 1959 Origin of Species by Natural Selection states that "Animals and plants increase at a prolific rate, but do not over-run the earth, and since individuals are all different then only reproductively "fit" or best adapted survive to reproduce. Benjamin Franklin also held this view, but much earlier than Darwin. T/F?
true
After Mendel's work was discovered, arguments arose over the mechanism of evolution and Lyell and Darwin developed the mutation theory that proposed that mutation was more important than natural selection in explaining why organisms change. T/F?
false
NeoDarwinism or Modern Synthesis would not include which of the following aspects of factors known to operate on evolution of plants and animals.
Lamarkianism
A temporary pond is a very unstable environment. That such ponds today are similar to those in JURASSIC time could be explained by views of___.
Lyell and Hutton
Who predicted such events as the famine in the 1840s in Ireland where the introduction of a new food source for the Irish allowed their population to soar until along comes the potato blight?
Malthus
Which of the following individuals read Malthus' paper and also came up with the idea of natural selection, but did not get much credit for it?
Wallace
Anaximander (525 B.C.) who believed that organisms evolve through time and become different kinds of organisms and Empedocles (450 B.C.) tried to further the concept of one organism changing into another organism. Believed life from organic "muck". T/F?
true
Any debate on evolution in ancient Greece died with the rise of Christianity and the decline of science. T/F?
true
Bishop Ussher decided the earth was created 4004 BC and Buffon- proposed the earth was 70,000 years old, and that some species might change over time. Who disproved both of these views by using geologic evidence?
Lyell and Hutton
Breeding the F1 offspring back to one of the parents is referred to as___?
introgression