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28 Cards in this Set

  • Front
  • Back

Dna

Contains instructions used in devlopment and functioning of all living organisms

Genome

Complete set of genetic informstion for organism

Rna

Crucial for taking dna instructions and making protiens that run the cell

Monomer

Nucleotide


Made of phosphate group, pentose sugar (deoxyribose or ribose), nitrogenous base

Polymer

Polynucleotide

Directionality

Twp ends 3' and 5'


3 ends in sugar


5 ends in phosphate

Dna polymerese

Requires 3' OH to add nucleotide


Builds dna strand by adding nucleotides to 3 end

Complementary base pairs

Specific base pairing


A-T C-G

Dna replication

Occurs before cell division in the nucleous

Helicase

Unwinds double helix and seperates dna strands

Topoisomerase

Releaves cpiling ahead of replication fork

DNA polymerses lll

Needs existing strand of dna to start dna synthesis at 3' end

Primase

Builds a primer a short rna molecule complementary to template

Leasing strand

Continous dna synthesis on strand made toward replication fork following helicase

Lagging strand

Discontinous dna synthesis, mulitple primers, conposed pf okazaki fragments

Dna pol 1

Removes rna primers and fills gap in with nucleotides

Dna ligase

Connects final bond of two okazaki fragments where dna pol 1 filled in gap

Telomeres

Ends of chromosome


Streches of repeated bases that do not contain genes


Protective caps to prevent dna shortening

Germaline cells

Stem cell, sperm and egg cells, embryonic cells


Contain telomeres that replicate telomores

Mismatch repair system

Removes and replaces incorrectly paired nucleotides resulting from replication errors


Endonuclease

Gut out mistakes

Excision repair

Replaces damage done by mutagens thay occur after cell divsion including uv light

Nucleosome

8 histones

Solenoid

Nuclesome wrapped up

Looped domains

Solenoid bind to lamin proteins of nuclear lamin

Metaphase chromosome

Only seen during cell divison


One very long dna molecule

Hayflick limit

Limit of 40 cell divisons average before cell death

Single sttand binding protiens

Stablize template strand and stop strans from pairing up