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28 Cards in this Set
- Front
- Back
Dna |
Contains instructions used in devlopment and functioning of all living organisms |
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Genome |
Complete set of genetic informstion for organism |
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Rna |
Crucial for taking dna instructions and making protiens that run the cell |
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Monomer |
Nucleotide Made of phosphate group, pentose sugar (deoxyribose or ribose), nitrogenous base |
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Polymer |
Polynucleotide |
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Directionality |
Twp ends 3' and 5' 3 ends in sugar 5 ends in phosphate |
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Dna polymerese |
Requires 3' OH to add nucleotide Builds dna strand by adding nucleotides to 3 end |
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Complementary base pairs |
Specific base pairing A-T C-G |
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Dna replication |
Occurs before cell division in the nucleous |
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Helicase |
Unwinds double helix and seperates dna strands |
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Topoisomerase |
Releaves cpiling ahead of replication fork |
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DNA polymerses lll |
Needs existing strand of dna to start dna synthesis at 3' end |
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Primase |
Builds a primer a short rna molecule complementary to template |
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Leasing strand |
Continous dna synthesis on strand made toward replication fork following helicase |
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Lagging strand |
Discontinous dna synthesis, mulitple primers, conposed pf okazaki fragments |
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Dna pol 1 |
Removes rna primers and fills gap in with nucleotides |
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Dna ligase |
Connects final bond of two okazaki fragments where dna pol 1 filled in gap |
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Telomeres |
Ends of chromosome Streches of repeated bases that do not contain genes Protective caps to prevent dna shortening |
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Germaline cells |
Stem cell, sperm and egg cells, embryonic cells Contain telomeres that replicate telomores |
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Mismatch repair system |
Removes and replaces incorrectly paired nucleotides resulting from replication errors |
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Endonuclease |
Gut out mistakes |
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Excision repair |
Replaces damage done by mutagens thay occur after cell divsion including uv light |
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Nucleosome |
8 histones |
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Solenoid |
Nuclesome wrapped up |
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Looped domains |
Solenoid bind to lamin proteins of nuclear lamin |
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Metaphase chromosome |
Only seen during cell divison One very long dna molecule |
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Hayflick limit |
Limit of 40 cell divisons average before cell death |
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Single sttand binding protiens |
Stablize template strand and stop strans from pairing up |