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61 Cards in this Set

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Deoxyribonucleic acid (DNA)

The molecule of heredity common to all life forms, that is passed from generations

Life instructions

DNA

Instruction manual for life

Chromosomes

Single, large DNA molecule wrapped around proteins


Located in nuclei of most eukaryotic cells

How many chromosomes do humans have?

23 pairs, one from mom and dad

XX

Female

XY

Male

Nucleotides

DNA made up of subunits linked together

Nucleotide parfa

Sugar, phosphate, a base

Double Helix

The spiral structure formed by two strands of DNA nucleotides bound together

Adenine

Pairs with thymine or uracil

Guanine

Pairs with cytosine

DNA profile

A visual rep of a persons unique DNA sequence

DNA replication

The natural process by which cells make an identical copy of a DNA molecule

Why do Certain nucleotides pair together?

Complementary - They are the right shape to form hydrogen bonds with each other, a always with T and C with G

1. Step of DNA rep

Helix is unwound and 2 strands unzip

2 step of DNA replication

DNA polymerase builds new strand of DNA along each unzipped strand: free nucleotides are added to each new strand in sequence

DNA polymerase

An enzyme that "reads" the sequence of a DNA strand and helps to add complementary nucleotides to form a new strand during DNA replication

3 step of DNA replication

End result is 2 complete double-stranded molecules of DNA

Semiconservative

DNA Replication is said to be Semiconservative because each newly made DNA molecule has one original and one new strand of DNA pol

Polymerase chain reaction

A lab technique used to replicate and thus amplify a specific DNA segment

Genome

One complete set of genetic instructions encoded in the DNA of an organism

Short tandem repeats

Sections of a chromosomes in which DNA sequences are repeated

Protein

A macromolecule made up of repeating subunits known as amino acids, which determine shape and function of a proteins. Proteins play many critical roles in living organisms

Gene

A sequence of DNA that contains the info to make at least one protein

How proteins form

Amino acids bind together In linear chains

Amino acids

The building blocks of proteins

Gene expression

The process of using DNA instructions to make proteins

Antithrombin

Promotes blood clotting

Alleles

Different versions of the same gene, with different nucleotide sequences

Transcotpion

Using DNA to make messenger RNA (mRNA) copy of the gene

Translation

The process of using this mRNA copy as a set of instructions to assemble amino acids into a protein

RNA polymerase

Transcription begins in the nucleus of a cell when an enzyme RNA polymerase binds to DNA at a genes regulatory sequence.

Trans

Back (Definition)

Trans

Ribosome

Where translation starts

Codon

It's letters name a particular amino acid

Transfer RNA

What delivers proteins/amino acids to the to ribosome

Anticodon

Base pairs are complementary fashion with an mRNA codon

Genetic code

The set of rules dictating with mRNA codons specify which amino acids

Interphase

G1 - cell grows


Synthesis - DNA replicates


G2 - ready to divide

Interphase

G1 - cell grows


Synthesis - DNA replicates


G2 - ready to divide

Mitosis

2. Phase of cell cycle


When the chromosomes are evenly divided between the two daughters cells

Cytokinesis

Last phase - The two daughter cells physically separate

Sister chromatid

Duplicates chromosome which connect to centromeee

Microtubules

Cells cytoskeleton, rearrange to form mototic spindle

Cell cycle checkpoint

Monitor stage of cell and check for mistakes

Apoptosis

Programmed cell death

Tumor

Mass of cells resulting from uncontrollable cell division

Mutations

A change in the nucleotide sequence of DNA

Germ-like mutation


Mutation occurring on gametes and passed to offspring

Somatic mutations

A mutation that occurs in a body, nongamete, cell - not passed to offspring

Germ-like mutation


Mutation occurring on gametes and passed to offspring

Somatic mutations

A mutation that occurs in a body, nongamete, cell - not passed to offspring

Mutagens

Chemical of physical agent that can damage DNA by changing its nucleotide sequence

Carcinogens

Chemical agent that causes cancer by damaging DNA - type of mutagen

Porto-oncogene

A gene that codes for a protein that helps cells divide normally

Porto-oncogene

A gene that codes for a protein that helps cells divide normally

Tumor suppressor gene

A gene that codes for proteins that monitor and check cell suckle progression. When these genes mutate, tumor suppressor proteins lose normal function

Oncogene

A mutated and overactive form of a proto-oncogene. Oncogenes drive cells to divide continually

Benign tunor

A non cancerous tumor that will not spread to the rest of the body

Malignant tumor

A cancerous tumor that spreads throughout the body