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51 Cards in this Set

  • Front
  • Back

clone

genetically identical copy of an organism

Somatic Cell Nuclear Transfer (SCNT)

reproductive cloning method in which the DNA of an adult donor's body cell is transferred into an unfertilized egg

Reproductive Cloning

any of several laboratory procedures that produce genetically identical animals

Differentiation

process by which cells become specialized during development

Hershey and Chase

Infected bacteria with a virus. Found that the DNA, not the protein passed on the virus.


Chargaff's Rules

The amounts of Thymine and Adenine are identical, as are the amounts of Cytosine and Guanine


A=T and G=C




the DNA of different species differs in the proportions of Adenine and Guanine

if the nucleotide sequence of one strand of DNA is AGTCAGTC what is the nucleotide sequence on the other?

TCGAGCGA

Roslind Franklin

Discovered structure of DNA by x-ray crystallography

Maurice Wilkins

Experimental evidence of DNA structure. Worked with Franklin.

Watson and Crick

Built the first accurate model of a DNA molecule.

DNA

the molecule of inheritance in all organisms.


Made up of a five-carbon sugar, phosphate groups, and a nitrogen containing base.


Consists of two nucleotide strands coiled into a double helix.


Hydrogen bonding between internally positioned nucleotide bases (A pairs with T, and C pairs with G) hold the two strands together. has a sugar-phosphate backbone

What sugar is in DNA

deoxyribose

Nitrogen Bases


A


G


T


C

A-Adenine


T-Thymine


C-Cytosine


G-Guanine

Edwin Chargaff

Found the nitrogen bases. The A&T are equal and paired and the G&C are equal and paired. if you know the % of one of the bases, you can determine the % of all 4 bases

How many hydrogen bonds do A&T share?

2

How many hydrogen bonds do C&G share?

3

Diploid Number

Having two of each type of chromosomes characteristic of the species (2N)

Karyotype

image of an individual's complement of chromosomes arranged by size, length, shape, and centromere location

Autosome

a chromosome that is the same for males and females

sex chromosome

23rd pairing. Member of a pair of chromosomes that differ between males and females

XY pairing

male

XX pairing

female

mutation

a permanent change in the nucleotide sequence

gene

a DNA sequence that encodes an RNA of protein product in the sequence of its nucleotide bases (A,T,G,C)

Transcription

enzymes use the gene's DNA sequence as a template to assemble a strand of messenger RNA




mRNA

translation

the protein-building information in mRNA is decoded into a sequence of amino acids

gene expression

process by which the information in a gene becomes converted to an RNA or protein product




proteins (enzymes) assemble other molecules and perform many functions that keep the cell alive

centromere

of a duplicated eukaryotic chromosome, constricted region where sister chromatids attach to each other

chromosome

structure that consists of DNA together with associated proteins. carries part or all of a cell's genetic information

chromosome number

the total number of chromosomes a cell of a given species

DNA sequence

order of nucleotides in a strand of DNA

histone

type of protein that associates with eukaryotic DNA and structurally organizes chromosomes

sister chromatids

the two attached DNA molecules of a duplicated eukaryotic chromosome

DNA replication

Process by which a cell duplicates is DNA before it divides

DNA polymerase

enzyme that carries out DNA replication

primer

short, single strand of DNA that base pairs with a specific DNA sequence

________ is an example of reproductive cloning


a. somatic cell nuclear transfer (SCNT)


b. multiple offspring from the same pregnancy


c. artificial embryo splitting


d. a and c


e. all of the above

d

which is not a nucleotide base in DNA?


a. adenine


b. guanine


c. glutamine


d. thymine


e. cytosine


f. all are in DNA

c

what are the base-pairing rules for DNA?


a. A-G, T-C


b. A-C, T-G


c. A-T, G-C


d. A-A, G-G, C-C, T-T

c

Variation in _____ is the base of variation in traits.


a. karyotype


b. DNA sequence


c. the double helix


d. chromosome number

b

one species' DNA differs from other in its _____.


a. nucleotides


b. DNA sequence


c. double helix


d. replication process


e. sugar-phosphate backbone


f. all of the above

b

in eukaryotic chromosomes, DNA wraps around _____.


a. histone proteins


b. sister chromatids


c. centromeres


d. nucleotides

a

Chromosome number _____.


a. refers to a particular chromosome in a cell


b. is a characteristic feature of a species


c. is the number of autosomes in cells of a given type


d. is the same in all species

b

Human body cells are diploid, which means they _____.


a. are complete


b.have two sets of chromosomes


c. contain sex chromosomes


d. divide to form two cells



b

When DNA replication begins, _____.


a. the two DNA strands unwind from each other.


b. the two DNA strands condense for base transfers.


c. old strands move to find new strands


d. mutations occur

a

DNA replication requires _____.


a. DNA polymerase


b. nucleotides


c. primers


d. all are required



d

Energy that drives the attachment of a nucleotide to the end of a growing strand of DNA comes from _____.


a. phosphate-group transfers from ATP


b. DNA polymerase


c. the nucleotide itself


d. a and c

c

after DNA replication, a eukaryotic chromosome _____.


a. consists of two sister chromatids


b. has a characteristic X shape


c. is constricted at the centromere


d. all of the above

d

Exposure to _____ can lead to mutations


a. UV light


b. cigarette smoke


c. chemicals


d. x-rays


e. sunlight


f. all of the above

f

all mutations _____.


a. arise from DNA damage


b. lead to evolution


c. are caused by radiation


d. change the DNA sequence

d

Match the terms appropriately


__ nucleotide a. replication enzyme


__ clone b. does not determine


sex


__ autosome c. copy of an organism


__ DNA polymerase d. nitrogen containing


base, sugar, phosphate


__mutation e. injects DNA


__ semiconservative f. can cause cancer


replication


__

d


c


b


a


f


e


g