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16 Cards in this Set
- Front
- Back
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What three types of filaments make up the cell? |
1. microfilaments 2. microtubules 3. intermediate filaments |
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what are the features of non-contractile actin? |
1. parallel actin filaments 2. short crosslinker = fimbrin or villin 3. myosin can't fit between, so non-contractile |
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what are the features of contractile actin bundles? |
1. non-parallel actin filaments 2. longer cross-linkers: alpha-actin 3. myosin can fit, so it pulls to contract 4. uses myosin 2 |
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how does stereocilia work? |
bent by sound waves; they're mechanically gated |
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what is focal adhesion? |
it's one end of a stress fiber, that has integrin |
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how do cells move? |
actin and Arp 2/3 |
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how does filipodia work? |
nucleates act as filaments; fimbrin moves forward |
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how does lamellipodium work? |
Arp2/3 nucleates actin filaments causes branching to push forward at 70* |
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how do bacterias move around cells? |
atp and arp2/3 hijacked by bacteria |
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what does each of the myosin classes do? |
miosin I: membrane association, endocytosis miosin II: contraction myosin VI&VII: anchor stereocilia |
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what are each of the crosslinkers for: |
fimbrin: filopodia, microvilli, focal adhesion alpha-actin: stress fibers, filopida filamin: lamellipodia |
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Where is actin found in an average cell: |
cortical network stress fibers when dividing: contractile ring |
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where is actin found in a moving cell: |
cortical network stress fibers contractile ring when dividing filapodia lamellipodia |
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in lamellipodia, the actin network is found at the _______ of the cell, and it _________ ARP 2/3 platforms to push forward
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at the leading edge
polymerizes |
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this type of actin is a support for all cells, and is NOT at the front of leading edge of moving cells |
cortical actin |
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______ and _____ are permanent non-contractile structures, while _______ comes and goes |
1. Microvilli 2. Stereocillia 3. Filipodia |
