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18 Cards in this Set

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Benign Fibro-Osseos Lesion


definition

Benign fibro-osseous lesion:


non-neoplasm


cellular fibrous tissue


irregular woven trebecular


- diverse biological behaviour with same microscopic appearance

BFOL- Types (3)

1. Central Ossyfiying Fibroma


2. Fibrous Dysplasia


3. Cemento-Osseous Dysplasia


3.1. Periapical cemental dysplasia


3.2. Focal cemento-osseous dysplasia


3.3. Florid cemento-osseous dysplasia

1. Central Ossifying Fibroma

A benign neoplasm (has intrinsic growth pattern; grows slowly unabated until removed), but NOT malignant

2. Fibrous Dysplasia (definition)

- Normal bone replaced by a BFOL leads to slow expanding, painless swelling, often leading to facial asymmetry in the jaws


- Fibro-­osseous stuff is not good bone: not lined up well, just a mesh of bone + cellular fibrous CT ­


- mutation of GNAS1 gene


- early childhood mutation so not inherited

2. Fibrous Dysplasia


Clinical

asymmetry and when you feel it's bony hard



2. Fibrous Dysplasia


Radiological

ground glass radiographic appearance (blending at borders with normal bone). No distinct, clear margin (if you see a clear delineation in radiograph, NOT fibrous dysplasia)

ground glass radiographic appearance (blending at borders with normal bone). No distinct, clear margin (if you see a clear delineation in radiograph, NOT fibrous dysplasia)


2. Fibrous dysplasia


Histological

not well organized bone with cellular fibrous CT everywhere 

not well organized bone with cellular fibrous CT everywhere

2. Fibrous Dysplasia


TX

do nothing


when growth stops Fibrous dysplasia stops too

2. Fibrous Dysplasia


Differnet forms (4)

2.1. Fibrous dysplasia Monostotic (single bone)


M=F, children, Maxilla>Mandible


80% of all fibrous dysplasia


2.2. Fibrous dysplasia Polystototic


>= 2 bones


2.3. Jaffe syndrome


polystotic, cafe-au-lait spots on skin/mucosa


2.4. McCune-Albright syndrome


polystotic, cafe, endocrinopathy (hyperthyro)

3. Cemento-osseous dysplasia


definition

most common BFOL that is always in the jaws


Different Stages:


1. Osteolytic stage


- removal of normal bone so radiolucency


2. Active stage


- deposition of crappy bone


- radiolucency with radiopacities everywhere


3. Mature Stage


- radiopacities fuse = hard mass + radiolucent rim


3. Cemento-osseous dysplasia


Types (3)

3.1. Periapical Cemento-osseous dysplasia


3.2. Focal Cemento-osseous dysplasia


3.3. Florid Cemento-osseous dysplasia

3.1. Periapical Cemento-osseous Dyplasia


Clinicial fts

- typically Middle aged, Black Females


- anterior mandible near apex of teeth mimics PAG/RAD so check vitality


- asymptomatic, multifocal lesions

3.1. Periapical Cemento-osseous Dysplasia


Osteolytic stage


teeth vital


painless


no jaw expansion


Tx: NONE, self-limiting


3.1. Periapical Cemento-osseous Dysplasia


- Histological

cellular fibrous CT


irregular trebecular bone 

cellular fibrous CT


irregular trebecular bone

3.2. Focal Cemento-osseous Dysplasia


Clinical fts

- middle aged females (may not be black)


- not at anterior mandible, its at posterior mandible usually


- painless and no expansion

3.3. Florid Cemento-osseous Dysplasia


Clinial Fts

- typically middle aged black females


- multiple quadrants


- osteolytic and active (developing) stages is asymptomatic but when mature and dense/hard it may get infected = painful (difficult to tx with Abk)


3.3. Florid Cemento-osseous dysplasia


Tx

Observation


Surgical removal of infected lesion

Meow