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5 Cards in this Set
- Front
- Back
Four Groups of Postraumatic Stress Syndromes
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1. Dissociation (ASD only?)
2. Intrusion 3. Avoidance 4. Hyperarousal |
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4 Useful predictors of PTSD
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1.***Persistence of PT symptoms for >10-14 days
2. Immediate pre-trauma psychiatric history 3. Previous trauma experience 4. Perceived social support |
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Neuroendocrinology of PTSD
-Catecholamines -Glucocorticoids |
Catecholamines
-abnormal urinary NE, EPI -Downregulation of Alpha-adrenergic receptors -Yohimbine can trigger flashbacks and panic attacks Glucocorticoids -Dexamethasone hypersuppression -Decreased?? 24 hr cortisol secretion --->rapid response and shutoff |
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Neurophsyiology of PTSD
-Psychophysiology -Event related potentials |
Psychophysiology
-hyper-responsiveness and decreased habituation Event related potentials -impaired attention and stimulus discrimination |
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Neuroanatomy of PTSD
-Imaging -Biological model |
Imaging
-smaller hippocampal volume Model -Event normally dually triggers amygdala (emotion) and hippocampus (context) -High cortisol levels thought to inhibit hippocampal pathways |