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9 Cards in this Set
- Front
- Back
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alcohol's real name? abbreviation and chemical formula
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Alcohol = ethanol (ETOH)= CH—CH—OH
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where is ethanol absorbed and how is it transported?
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Ethanol is readily absorbed from gi tract & is
transported unaltered in the bloodstream |
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what is calorie value of alcohol?
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7 kcal/g
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what percent of alcohol ingested can be metabolized?
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90%
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How many grams of ethanol can a person metabolize per hour?
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5-7 grams per hour
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what are the 2 main enzyme systems for metabolizing ethanol?
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1) Alcohol Dehydrogenase (ADH) Pathway
2) Microsomal Ethanol Oxidizing System (MEOS) |
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1) Alcohol Dehydrogenase (ADH) Pathway
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takes place when ETOH in low-moderate concentrations
ADH is in cytoplasm (liver) & requires NAD+ (H acceptor) ADH also found in gastric mucosa (males > females) first step : oxidizes ETOH to acetaldehyde(CH3-CHO) + NADH, H+ NADH can be oxidized for ATP in electron transport system |
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other location of ADH
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ADH also found in gastric mucosa (males > females)
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Acetaldehyde is toxic to cells
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Attaches to proteins & alters function & structure
(cirrhosis) Contributes to “hangover” symptoms Some ethnicities (Asians) have special forms of ADH that promote rapid production of acetaldehyde, which makes the drinker feel sick |
