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47 Cards in this Set
- Front
- Back
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putamen - w/caudate = striatum = input nuclei; damage = Huntington's (personality changes, erratic mvmt); gaba/enk - w/global pallidus = lentiform nucleus - w/ caudate and global pallidus = corpus striatum |
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head of the caudate nucleus - w/putamen = striatum; striatum=input nuclei - input for basal ganglia - damage = huntington's; personality changes, erratic mvmt); gaba/enk |
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septal nuclei |
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nucleus accumbens - pleasure center |
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olfactory tract - axons of lateral stria go to amygdala |
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optic nerve - synapse in lateral geniculate body to superior colliculus |
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amygdala - damage = Kluver-Bucy syndrome = psychic blindness, hyperoral, hypersexual, no fear - projects to dorsal medial thalamus |
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head of caudate nucleus - w/putamen = striatum = input nuclei - input for basal ganglia - damage = huntington's; personality changes, erratic mvmt); gaba/enk |
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globus pallidus - w/putamen = lentiform nucleus |
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putamen - w/caudate = striatum= input nucelei; damage = Huntington's (personality changes, erratic mvmt); gaba/enk - w/global pallidus = lentiform nucleus - w/ caudate and global pallidus = corpus striatum |
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substantia innominata - aka subcommissural region - aspiny neurons = cholinergic - damage = dementia |
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anterior commissure |
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column of the fornix - hippocampus to fimbria of fornix to fornix to mammillary bodies (via posterior to anterior commissure) OR to septal nuclei (anterior to anterior commissure) |
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medial pallidal segment (MPS) - direct pathway: striatum (putamen & caudate) to MPS to substantia nigra pars reticulata to thalamus - output nuclei for basal ganglia - GABA/substance P = spiny neurons - favors movement - ACh from cortex inhibits direct pathway - dopamine from SNc activates direct pathway |
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body of the caudate nucleus - w/putamen = striatum = input nuclei - input for basal ganglia - damage = huntington's; personality changes, erratic mvmt); gaba/enk |
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amygdala - damage = Kluver-Bucy syndrome = psychic blindness, hyperoral, hypersexual, no fear - projects to dorsal medial thalamus |
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posterior limb of internal capsule |
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lateral pallidal segment - indirect pathway: striatum (putamen & caudate) to LPS to subthalamic nuclei to MPS and substantia nigra pars reticulata - GABA/enkaphalin spiny neurons - inhibits movement - ACh from cortex activates indirect pathway - dopamine from SNc inhibits indirect pathway |
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optic tract - damage = contralateral homonymous hemianopsia (no contralateral input from either eye) |
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body of the fornix - hippocampus to fimbria of fornix to fornix to mammillary bodies (via posterior to anterior commissure) OR to septal nuclei (anterior to anterior commissure) |
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lateral pallidal segment - indirect pathway: striatum (putamen & caudate) to LPS to subthalamic nuclei to MPS and substantia nigra pars reticulata - GABA/enkaphalin spiny neurons- inhibits movement - ACh from cortex activates indirect pathway - dopamine from SNc inhibits indirect pathway |
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hippocampal formation |
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substantia nigra - damage = Parkinson's b/c dopamine degeneration in pars compacta - dopaminergic neurons excite GABA/sub P in putamen to MPS - dopaminergic neurons inhibit GABA/enk in putamen to LPS - facilitates movement |
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subthalamic nucleus - damage = hemiballismus (hyperkinetic) - glutamatergic axons - project to MPS and substantia nigra pars reticularis |
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medial pallidal segment (MPS) - direct pathway: striatum (putamen & caudate) to MPS to substantia nigra pars reticular to thalamus - output nuclei for basal ganglia- GABA/substance P = spiny neurons - favors movement - ACh from cortex inhibits direct pathway - dopamine from SNc activates direct pathway |
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inferior horn of lateral ventricle |
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tail of caudate nucleus - w/putamen = striatum = input nuclei - input for basal ganglia - damage = huntington's; personality changes, erratic mvmt); gaba/enk |
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fimbria of fornix - hippocampus to fimbria of fornix to fornix to mammillary bodies (via posterior to anterior commissure) OR to septal nuclei (anterior to anterior commissure) |
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inferior horn of the lateral ventricle |
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lateral geniculate body |
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putamen - w/caudate = striatum = input nuclei; damage = Huntington's (personality changes, erratic mvmt); gaba/enk - w/global pallidus = lentiform nucleus - w/ caudate and global pallidus = corpus striatum |
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genu of internal capsule |
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medial pallidal segment (MPS) - direct pathway: striatum (putamen & caudate) to MPS to substantia nigra pars reticular to thalamus - output nuclei for basal ganglia- GABA/substance P = spiny neurons - favors movement - ACh from cortex inhibits direct pathway - dopamine from SNc activates direct pathway |
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optic radiations |
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anterior limb of internal capsule |
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head of caudate nucleus - w/putamen = striatum = input nuclei - input for basal ganglia - damage = huntington's; personality changes, erratic mvmt); gaba/enk |
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posterior limb of the internal capsule |
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lateral pallidal segement - indirect pathway: striatum (putamen & caudate) to LPS to subthalamic nuclei to MPS and substantia nigra pars reticulata - GABA/enkaphalin spiny neurons- inhibits movement - ACh from cortex activates indirect pathway - dopamine from SNc inhibits indirect pathway |
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mammillary body - damage = chronic alcohol abuse = degeneration = Karsakoff's syndrome (compensatory confabulation, memory loss) |
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optic tract - damage = contralateral homonymous hemianopsia (no contralateral input from either eye) |
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amygdala - damage = Kluver-Bucy syndrome = psychic blindness, hyperoral, hypersexual, no fear - projects to dorsal medial thalamus |
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hippocampus |
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substantia nigra - damage = Parkinson's b/c dopamine degeneration in pars compacta - dopaminergic neurons excite GABA/sub P in putamen to MPS - dopaminergic neurons inhibit GABA/enk in putamen to LPS- facilitates movement |
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inferior horn of lateral ventricle |
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substantia nigra, pars reticulata - indirect pathway: striatum (putamen & caudate) to LPS to subthalamic nuclei to MPS and substantia nigra pars reticulata - subthalamic nucleus glutamatergic axons project here and to MPS - output nuclei for basal ganglia - ACh from cortex activates indirect pathway - dopamine from SNc inhibits indirect pathway |
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substantia nigra, pars compacta - damage = Parkinson's b/c dopamine degeneration in pars compacta |
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lateral olfactory stria |
