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25 Cards in this Set
- Front
- Back
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What is the MC cause of phimosis in males?
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Lichen Sclerosis
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What HLA is associated with Lichen Sclerosis?
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HLA-DQ7 (in women and kids, but NOT MEN)
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Name the Dz:
Shiny, ivory colored scar with wrinkled atrophic skin “Figure of eight” encircling vulvar & perianal region Focal areas of erosions, fissures, & hyperkeratosis Telangiectasis late in disease RARELY hemorrhagic blisters |
Lichen Sclerosis
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What are common sites of Extra-Genital Lichen Sclerosis?
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Submammary area, sites of trama (trunk, proximal limbs)
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Another name for LS&A when on the glans penis?
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Balanitis Xerotica Obliterans (BXO)
- 60% of cases of phimosis - in 15% of boys with hypospadias |
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What are the three types of Genital LP?
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1. Plaque/Papule in generalized form (MC Type): is non scarring and itchy
2. Erosive LP (Vulvo-vaginal Gingival Syndrome) - scarring with extensive erosions, painful 3. Hypertrophic (Rare) |
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What % of Women with cutaneous LP have genital involvement?
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50%
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What drugs can induce LP?
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MN GAP ATAS
Gold Antimalarials Photocolor developer, Penicillamine Amphetamines Thiazides ACE inhibitors Statins |
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Zoon's balanitis/vulvitis aka?
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Zoon's erythroplasia
Plasma Cell Balanitis/Vulvitis Balanitis/Vulvitis Circumscripta Plasmacellularis |
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Name the Dz:
Erythematous, moist plaques with “cayenne pepper” speckled appearance Adjacent “kissing lesions” can be present Symptoms: Pruritus, Dysuria, and/or asymptomatic |
Zoon's Balanitis
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Which HPV strains is assoc with bowenoid papulosis (subtype of PIN that has better prognosis)?
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HPV 16 and 18
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High risk oncogenic HPV types are?
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HPV 16, 18, 31, 33
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Erythroplasia of Queyrat is caused by which HPV?
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Type 16
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HPV associations with which dz?
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What is the MC tumor of the anogenital region?
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SCC
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Which of the following is the most commonly affected site for extra-mammary Paget’s DZ?
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Vulva!
Perianal is 2nd most common |
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What malignancy is assoc with underlying Paget's Dz?
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Bladder & Rectum
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Name the Dz:
“Strawberries & cream” Well-defined red plaque w/ scattered areas of white scale & erosions Can look like eczema/dermatitis Sx: Classically burning or pruritis, but may be asymptomatic |
Extramammary Paget's
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Criteria for Behcet's dz?
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Recurrent oral ulcers (≥ 3 per yr)
PLUS 2 of the following: - Recurrent genital ulcer - Eye lesions - Skin lesions – EN, folliculitis - Pathergy test |
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What are the most common causes of fixed drug reactions?
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MN: SALT PP
Sulfa Acetaminophen / ASA Laxative (phenopthalein) - phenopthalein also found in cheap wine Tetracycline Pseudoephedrine Phenylbutazone |
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Which is the most frequent symptom seen with Lichen Sclerosus?
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Itching
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Name inheritance of white sponge nevus
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Autosomal Dominant, Defect in keratins 4 & 13
-Generally benign & asymptomatic -Requires NO specific therapy |
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Describe: Recurrent Toxin Mediated Perineal Erythema
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Presents 2-3 days after throat infection (strep or staph pharyngitis)
CLINICAL: Fine, diffuse macular erythema of perineal area Local edema Desquamation follows erythema Similar Sx may also occur on hands Sx frequently recur…hence the name NO systemic Sx (fever, hypotension) |
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Name the dz:
Presents 2-3 days after throat infection (strep or staph pharyngitis) CLINICAL: Fine, diffuse macular erythema of perineal area Local edema Desquamation follows erythema Similar Sx may also occur on hands Sx frequently recur…hence the name NO systemic Sx (fever, hypotension) |
Recurrent Toxin Mediated Perineal Erythema
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Name the Dz:
Necrotizing infection Classically occurs in diabetics & immunosuppresed Etiology: Poly-microbial |
Fournier's Gangrene
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