Ati Respiratory System Meds (Upper Respiratory Drugs)

Front 1

antitussives -opioids

Back 1

proto: codeine
other: hydrocodone

Front 2

antitussive opioid MOA

Back 2

supresses cough through its action on the central nervous system

Front 3

antitussive opiod use (codeine)

Back 3

chronic non-productive cough

Front 4

antitussive opioid (codiene) adverse

Back 4

CNS effects
GI distress
potential for abuse

Front 5

antitussive contraindications (codeine)

Back 5

pregancy risk C
acute asthma, head trauma, liver and renal disease, acute alcoholism

Front 6

antitussive opioid interventions (codiene)

Back 6

avoid CNS depressants while taking codeine

Front 7

antitussive-nonopioid

Back 7

proto: dextromethorphan
others: benzonatate (Tessalon), diphenhydramine (Benadryl)

Front 8

antitussive non-opioid MOA

Back 8

supresses cough through its action on the CNS. Although it is not an opioid, it is derived from opioids

Front 9

antitussive non-opioid use

Back 9

cough suppression

Front 10

antitussive non-opioid adverse

Back 10

few adverse effects
nausea, dizziness, sedation may occur
some potential for abuse

Front 11

antitussive non-opioid contraindications

Back 11

pregnancy risk c

Front 12

antitussive non-opioid interactions

Back 12

can cause high fever whe nused within 2 weeks of MAOI antidepressants

Front 13

antitussive non-opioid interventions

Back 13

may contain alcohol or sucrose
capsules, lozenges, liquids, and syrups

Front 14

antitussive non-opioid effectiveness

Back 14

absence or decreased episodes of coughing

Front 15

expectorants

Back 15

proto: guaifenesin (Mucinex)

Front 16

guaifenesin MOA

Back 16

promotes increased cough production through increasing mucous secretion, allows client to decrease chest congestion by coughing out secretions

Front 17

guaifenesin uses

Back 17

often combined with antitussives or a decongestant for treating symptoms of colds, allergies, or nonallergic rhinitis, or for cough caused by lower respiratory disorders

Front 18

guaifenesin adverse

Back 18

GI upset, drowsiness, dizziness, allergic reaction (rash)

Front 19

guaifenesin contraindications

Back 19

pregnancy category C
if breastfeeding, talk to provider
depending on formulation and med combinations- preparations containing guaifenesin may not be recommended for children

Front 20

guaifenesin interventions

Back 20

increase fluid intake to promote liquifying secretions

Front 21

guaifenesin effectiveness

Back 21

cough is more productive and mucous is easier to expectorate
chest congestion is decreased

Front 22

mucolytics

Back 22

proto: acetylcholine (Mucomyst, Acetadote)
other meds: hypertonic saline

Front 23

mucolytics MOA

Back 23

enhance the flow of secretions in the respiratory passages

Front 24

mucolytics uses

Back 24

acute and chronic pulmonary disorders exacerbated by large amounts of secretions
mucolytics are used in clients who have cystic fibrosis
acetylcysteine is the antidote for acetaminophen poisoning

Front 25

mucolytics adverse

Back 25

aspiration and bronchospasm when administered orally

Front 26

mucolytics contraindications

Back 26

pregnancy risk B
should not be used in clients at risk for GI hemorrhage
PUD, esophageal varices, and severe liver damage
due to potential for bronchospasm, acetylcysteine should be used cautiously in clients who have asthma

Front 27

mucolytics admin

Back 27

acetylcysteine has an odor like rotten eggs
acetylcyestine is adminstered by inhalation to liquify nasal and bronchial secretions and facilitate coughing
administered orally or IV for acetaminophen overdose

Front 28

mucolytic effectiveness

Back 28

improvement of manifestations as demonstrated by regular respiratory rate, clear lung sounds, and increased rate of expectoration

Front 29

decongestants

Back 29

phenylephrine (Neo-Synephrine)
Other: ephedrine
naphazoline (Privine)
pseudoephedrine (Sudafed)

Front 30

decongestants MOA

Back 30

sympathomimetic decongestants stimulate alpha1 adrenergic receptors, causing reduction in the inflammation of the nasal membranes

Front 31

decongestants uses

Back 31

treats allergic or non allergic rhinitis by relieving nasal stuffiness
acts as a decongestant for clients who have sinusitis and the common cold

Front 32

decongestant adverse

Back 32

rebound congestion secondary to prolonged use of topical agents
CNS stimulation
vasoconstriciton

Front 33

decongestant contraindications

Back 33

chronic rhinitis
coronary artery disease and hypertension

Front 34

decongestant admin

Back 34

when administering nasal drops- clients should be in lateral, head-low position to increase desired effect and to prevent swallowing the medication
topical- more effective, works faster, shorter duration
oral agents do not lead to rebound congestion

Front 35

decongestant effectiveness

Back 35

improvement of manifestations

Front 36

antihistamines

Back 36

1st gen H1 antagonists:
diphenyhydramine (Benadryl)
prmethazine (Phenergan)
dimenhydrinate (Dramamine)

2nd gen H1 antagonists
loratadine (Claritin)
cetirizine (Zyrtec)
fexofenadine (Allegra)
desloratadine (Clarinex)

Intranasal antihistamines
azelastine (Astelin, Astepro)
olopatdine (Patanase)

Front 37

antihistamine MOA

Back 37

action is on H1 receptors, which results in the blocking of histamine release in the small blood vessels, capillaries, and nerves during allergic reactions
when used for upper respiratory infections, antihistamines relieve manifestations by suppressing mucus secretion because of their anticholinergic effect

Front 38

antihistamine use

Back 38

mild allergic reaction
anaphylaxis (hypotension, acute laryngeal edema, bronchospasm)
motion sickness
insomnia
often used in combination with sympathomimetics to provide a nasal decongestive effect

Front 39

antihistamine adverse

Back 39

GI discomfort
acute toxicity (flushed face, high fever, tachycardia, dry mouth, urinary retention, pupil dilation)
excitation, hallucinations, incoordination, and seizures in children

Front 40

antihistamine contraindications

Back 40

third trimester of pregnancy
breastfeeding
newborns
promethazine -pregnancy category C, cardiac dysrhythmias, hepatic diseases, and those taking MAOI
children, older adults, asthma, urinary retention, open-angle glaucoma, hypertension and prostate hypertrophy

Front 41

antihistamine interactions

Back 41

CNS depressants

Front 42

antihistamine interventions

Back 42

be aware of sedating side effects

Front 43

antihistamine effectiveness

Back 43

improvement of allergic reaction
relief of symptoms

Front 44

nasal glucocorticoids

Back 44

mometasone (Nasonex)
others: fluticasone (Veramyst)
triamcinolone (Nasacort)
budesonide (Rhinocort aqua)

Front 45

nasal glucocorticoids MOA

Back 45

decrease inflammation associated with allergic rhinitis
first line of treatment for nasal congestion

Front 46

nasal glucocorticoids use

Back 46

reduce effects of allergic rhinitis including sneezing, nasal itching, runny nose

Front 47

nasal glucocorticoids adverse

Back 47

sore throat, nosebleed, headache, burning in the nose

Front 48

nasal glucocorticoid contraindications

Back 48

risk c