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475 Cards in this Set
- Front
- Back
What is Dioctophyma Renale? |
the Giant Kidney Worm. |
|
Define Lymphopenia. |
A decrease in lymphocytes. |
|
Define Eosinopenia. |
A decrease in eosinophils. |
|
Define Glucosuria. |
The presence of glucose in the urine. |
|
Define Left Shift. |
When there is a higher number band neutrophils |
|
What are the 3 examples of granulocytes? |
Neutrophils |
|
What are Granulocytes? |
A white blood cell with secretory granules in its cytoplasm. |
|
What are Agranulocytes? |
White blood cells with a one-lobed nucleus. |
|
What are the 2 types of Agranulocytes? |
Monocytes Lymphocytes |
|
Of the granulocytes, which is the most common? |
Neutrophils |
|
Which is the most common agranulocyte ? |
Lymphocyte |
|
What is the scientific name of Coccidia? |
Isospora |
|
What is this a picture of? |
Coccidia. |
|
What is Dipetalonema reconditum a parasite which in its immature form can be confused with ? |
Dirofilaria immitis (heartworm). |
|
What are the three RBC indices? |
MCV MCH MCHC |
|
What does MCV stand for? |
Mean Corpuscular Volume |
|
What does MCV measure? |
The size of RBCs |
|
What is the formula for MCV? |
PCV x 10 / RBC |
|
What is the unit of measurement for MCV? |
fl |
|
What is the normal range for MCV? |
60-70fl |
|
What does MCH stand for? |
Mean Corpuscular Hemoglobin |
|
What does MCH measure? |
The weight of the hemoglobin |
|
What is the formula for MCH? |
Hgb x 10 / RBC |
|
What is the unit of measurement for MCH? |
pg |
|
What is a normal MCH? |
20pg. |
|
What does MCHC stand for? |
Mean Corpuscular Hemoglobin Concentration. |
|
What does MCHC measure? |
The concentration of hemoglobin |
|
What is the formula for MCHC? |
Hgb x 10 / PCV |
|
What is the unit of measurement for MCHC? |
g/dl |
|
What is a normal range for MCHC? |
30-36 g/dl. |
|
What is Paragonimus kellicotti? |
Lung fluke |
|
What genus is Paragonimus kellicotti? |
Trematode |
|
What is Dipylidium caninum? |
Tapeworm |
|
What is this a picture of? |
A tapeworm egg.
|
|
What is a T Lymphocyte? |
white blood cell which plays a central role in cell-mediated immunity. |
|
What is a B lymphocyte? |
A type of white blood cell which secretes antibodies. |
|
What is hemobartonella? |
A blood parasite |
|
What is this? It's found in urine. |
Capillaria plica |
|
What is a normal BUN? |
10-30 |
|
What does BUN stand for? |
Blood Urea Nitrogen |
|
What are 3 causes of icterus? |
1) Liver Problems 2) Hemolysis 3) Cholestasis (blockage of the bile duct) |
|
What is Dirofilaria immitis? |
Heartworm |
|
What are the 3 portions of a urinalysis? |
1) Gross 2) Physical 3) Chemical |
|
What is the arrow pointing to? |
Babesia |
|
List the 5 types of WBCs. |
1) Neutrophil 2) Lymphocyte 3) Monocyte 4) Eosinophil 5) Basophil |
|
List the 2 types of lymphocytes. |
1) B Lymphocytes 2) T Lymphocytes |
|
What is the function of B Lymphocytes? |
Involved with antibody production. |
|
What is the function of T Lymphocytes? |
Involved with cell mediated immunity. |
|
What is the significance of monocytes? |
They are associated with chronic inflammation. |
|
What are 4 possible causes of a stress leukogram? |
1) Muscular Activity 2) Increased Heart Rate 3) Increased Blood Pressure 4) Steroids |
|
Define neutropenia. |
Decrease in Neutrophils. |
|
True or False: Eosinophilic cytoplasmic granules vary in shape, size, and number. |
TRUE |
|
True or False: Canine eosinophils vary in size, are round to oval, and have cytoplasmic vacuoles. |
TRUE |
|
What shape are the eosinophilic granules in felines? |
Rod-like. |
|
True or False: Monocytes become macrophages in tissues. |
TRUE |
|
What are the 3 causes of anemia? |
1) Lack of Production 2) Blood Loss 3) Hemolysis |
|
What are the 4 signs of regenerative anemia? |
1) Anisocytosis 2) Polychromasia 3) Howell Jolly Bodies 4) Nucleated Red Blood Cells (NRBCs) |
|
What is the significance of ketones in the urine? |
Ketones are caused by fat metabolism and may indicate diabetes mellitis |
|
What is Ketonuira usually associated with? |
Metabolic Acidosis |
|
How long is a red blood cell's life span in cats? |
90 days |
|
How long is a red blood cell's life span in dogs? |
100-110 days |
|
What are 2 types of leptocytes? |
Bar Cells and Target Cells |
|
What is the arrow pointing to? |
A Bar Cell. |
|
What are the arrows pointing to? |
Target Cells. |
|
Define acanthocyte. |
Cells with oblique, thorny, projections. |
|
What is the significance of acanthocytes? |
They are frequently seen in hemolytic anemias or with liver disease. |
|
What is the arrow pointing to? |
Acanthocyte. |
|
What is the significance of spherocytes? |
They are seen in IMHA. |
|
What is the arrow pointing to? |
A Spherocyte. |
|
True or False: Heinz Body Cells are commonly seen in cats. |
TRUE |
|
What is the significance of Heinz Body Cells? |
Can be caused by ingestion of onions, toxic drugs (acetaminophen). |
|
Define echinocytes. |
Red blood cells with multiple, small, evenly distributed projections. |
|
What is the significance of echinocytes? |
Can be caused by renal disease or snake bites.
|
|
True or False: The most common cause of echinocytes is crenation. |
TRUE |
|
Define Schistocytes. |
Fragments of red blood cells. |
|
What is the arrow pointing to? |
A Schistocyte. |
|
What is a reticulocyte? |
An immature red blood cell that contains clumps of RNA. |
|
True or False: You can see reticulocytes when staining with Diff-Quick. |
FALSE, they can only be seen by staining with NMB. |
|
True or False: Reticulocytes are a sign of regeneration. |
TRUE |
|
What is the significance of Reticulocytes? |
It is used as a clinical index of Erythropoiesis (the production of red blood cells). |
|
What is the formula for Observed Reticulocytes? |
Observed = # counted / 1000 x 100 = _________% |
|
What is the formula for Corrected Reticulocytes? |
Observed x Patient PCV / Normal PCV = _______% |
|
What is the formula for Absolute Reticulocytes? |
# Counted x RBC Count (written out) = ________uL |
|
Which types of Reticulocytes do you count in the cat? |
Aggregate |
|
Of the two types of reticulocytes which on is older, punctate or aggregate? |
Punctate |
|
What is a normal RBC count? |
6-7 million. |
|
What is a normal WBC count? |
6,000 - 16,000. |
|
How do you find the hemoglobin estimated value? |
PCV/3. |
|
How do you find the RBC estimated count? |
PCV/6. |
|
What is a normal PCV for a cat? |
~37%. |
|
What is a normal PCV for a dog? |
~45%. |
|
Define dysuria. |
Difficult Urination. |
|
Define Isosthenuria. |
Urine with a Specific Gravity of 1.010, which is similar to that of glomerular filtrate. |
|
Define Glomerular Filtrate |
The fluid produced from blood by the glomerulus |
|
Define Pyelonephritis |
Bacterial infection in the kidney |
|
Define Polyuria |
Large amounts of urine |
|
Define Hematuria |
Blood in the urine |
|
Define Oliguria |
Decreased amounts of urine |
|
Define Anuria |
Lack of urine production |
|
Define Cystitis |
Inflammation of the Urinary Bladder |
|
Define Hemoglobinuria. |
The patient has red cloudy urine, but there are very few RBCs in the sediment |
|
Define Pyuria |
White/Cloudy urine with WBC's and Bacteria |
|
What is the scientific name of the hookworm? |
Ancylostoma caninum |
|
What is this a picture of? |
A hookworm egg. |
|
What is the scientific name for roundworms? |
Toxocara canis |
|
What is this a picture of? |
A roundworm egg. |
|
What genus is Toxocara Canis? |
Nematode |
|
What is the parasite typically associated with Raccoons? |
Baylisascaris procyonis. |
|
What is the scientific name for Whipworms? |
Trichuris vulpis |
|
Where do Whipworms live in the body? |
Cecum |
|
What is this a picture of? |
Whipworm Eggs |
|
What is the scientific name for tapeworms? |
Dipylidium caninum |
|
What genus are tapeworms? |
Cestodes |
|
What is this a picture of? |
A tapeworm egg. |
|
What is the scientific name for Coccidia? |
Isospora. |
|
What is this a picture of? |
Coccidia eggs. |
|
What is the scientific name of the stomach worm? |
Physaloptera Rara |
|
What is the scientific name for the Giant Kidney Worm? |
Dioctophyme renale |
|
What is the scientific name for the bladder worm? |
Capillaria Plica |
|
What is the current term for Hemobartonella? |
Mycoplasma haemofelis |
|
What does Mycoplasma haemofelis cause? |
FIA (Feline Infectious Anemia). |
|
What is Ehrlichia? |
A tick born disease. |
|
What is the most common type of flea found on both dogs and cats? |
The cat flea (Ctenocephalides felis) |
|
List the 4 stages of a flea lifecycle. |
1) Egg 2) Larvae 3) Pupae 4) Adult |
|
What organism causes Lyme Disease? |
Burrelia Burgdorfori |
|
What are the 3 types of granulocytes? |
1) Neutrophils 2) Basophils 3) Eosinophils |
|
What are the 3 causes of Leukocytosis? |
1) Infection 2) Stress 3) Inflammation |
|
What are the 2 causes of Leukopenia? |
1) Parvo (dogs) 2) Panleukopenia (cats) |
|
What is the normal range for Creatnine? |
1-2 |
|
What is a regenerative left shift? |
When there are more young WBCs in the blood with an increased WBC count with segmented neutrophils |
|
What type of drug can be associated with a lymphopenia? |
Steroid |
|
The scientific name of the mite associated with immune problems is what? |
Demodex. |
|
What are the 6 stages of a neutrophil? |
1) Myloblast 2) Promyloblast 3) Mylocyte 4) Metamylocyte 5) Band Neutrophil 6) Segmented Neutrophil |
|
What are the 6 stages of an erythrocyte? |
1) Rubriblast 2) Prorubricyte 3) Rubricyte 4) Metarubricyte 5) Reticulocyte 6) Erythrocyte |
|
What does FIP stand for? |
Feline Infectious Peritonitis |
|
What is FIP? |
A viral disease in cats caused by the corona virus |
|
What does FIV stand for? |
Feline Immunodeficiency Virus. |
|
What is FIV? |
A lentivirus |
|
What does FeLV stand for? |
Feline Leukemia Virus |
|
What is FeLV? |
A retrovirus |
|
What does IMHA stand for? |
Immune Mediated Hemolytic Anemia. |
|
What does AIHA stand for? |
Autoimmune Hemolytic Anemia. |
|
What does FIA stand for? |
Feline Infectious Anemia |
|
What is another name for FIA? |
Haemobartonellosis |
|
What is serum? |
The liquid portion of clotted blood |
|
What is plasma? |
The liquid portion of whole blood |
|
What is a normal Thyroid value range? |
1-4. |
|
What is this a picture of |
Metamyelocytes |
|
What is this a picture of |
Large granular lymphocyte |
|
What is this a picture of |
Reactive lymphocyte |
|
What is this a picture of |
Vacuolated Lymphocyte |
|
What is this a picture of |
Monocyte |
|
What is this a picture of |
Eosinophil |
|
What is this a picture of |
Basophil |
|
What is this a picture of |
Metarubricyte |
|
What is this a picture of |
Granulocytic lukemia |
|
What is this a picture of |
Monocytic lukemia |
|
What is this a picture of |
Megakaryoblasts |
|
Which of the following wbc's tend to have a kidney bean shaped nucleus:
|
metamyelocytes
|
|
A leukogram that shows a decrease of wbc's along with an increase of bands is termed a:
|
degenerative left shift
|
|
T or F: When performing a differential, the wbc count should always be reported in relative numbers in order to be diagnostically useful.
|
FALSE
|
|
T or F: Immunocytes are the same cell as a reactive lymphocyte
|
TRUE
|
|
T or F: It is easy to differentiate T and B lymphocytes based upon theirmorphology
|
FALSE
|
|
Which of the following is the most immature recognizable cell in the erythroid series?
|
rubriblast
|
|
Which cell in the WBC line is one stage less mature then the band neutrophil?
|
metamyelocyte
|
|
Abone marrow aspiration on a cat may be obtained from the
|
proximal humerus, femur, and the wing of the ileum
|
|
Which cell in the RBC line is the most immature, with a large nucleus and nucleoli still present?
|
rubriblast
|
|
In what species is a bone marrow sample the primary means buy which to judge the animals response to an anemia?
|
Equine
|
|
Abone marrow aspiration in small animals can sometimes be performed with whichof the following
|
Tranquilizer or General anesthetic
|
|
What does the term hyperplastic mean?
|
increased number of cells
|
|
T or F: When performing an M:E ratio you would count all mature nucleated cells with the bone marrow.
|
FALSE
|
|
About how many days does it take a RBC to mature?
|
5
|
|
When following a bone marrow case, besides actually examining the bone marrow what other lab test might the technician be performing?
|
CBC
|
|
T or F: Diagnostic cytology offers significant time savings in thedifferentiation between inflammatory disease and cancer
|
TRUE
|
|
T or F: It is ok to send cytology samples and formalin fixed samples to areference laboratory in the same box as long as they are wrapped and addressedproperly
|
FALSE
|
|
T or F: When performing a fine needle aspirate, the best technique is to directthe needle into the mass one time and then remove the needle from the animal
|
FALSE
|
|
T or F: The term for study of diseased tissues is histopathology
|
FALSE
|
|
When performing a fine needle aspirate, which of the following pieces of equipment is not advised
|
25 gauge needle
|
|
T or F: When examing cellular detail of a cytology sample, it is wise to use the10X objective
|
FALSE
|
|
T or F: Cytology seldom will provide a definitive diagnosis when used as the sole diagnostic test as other tests may be needed
|
TRUE
|
|
T or F: Exudates are an abnormal collection of normal fluid.
|
FALSE
|
|
T or F: Normal body cavities (pleural, peritoneal and visceral) are lined by mesothelial cells in variable numbers.
|
TRUE
|
|
Transudates are effusions that are relatively unique because of all of the following characteristics EXCEPT:
|
SPECIFIC GRAVITY >1.017
|
|
T or F: Congestive heart failure may result in an animal developing a transudateor a modified transudate
|
TRUE
|
|
TRUE or FALSE: Increased turbidity is most commonly associated with increased numbers of cellular elements.
|
TRUE
|
|
TRUE or FALSE: Transudates are a normal collection of abnormal fluid.
|
FALSE
|
|
TRUE or FALSE: Inflammation can be classified based upon its duration by the terms acute, subacute (same as chronic-active) or chronic inflammation.
|
TRUE
|
|
TRUE OR FALSE: Acute neutrophilic inflammation is less than 70% Neutrophils, normalneutrophils
|
FALSE
|
|
TRUE OR FALSE: Complete characterization of an effusion requires evaluation of various features such as the cellular content and specific gravity.
|
TRUE
|
|
Chronic inflammation is characterized by:
|
greater than 50% macrophages
|
|
TRUE OR FALSE: Collection of exfoliative cytology samples always requires at least local anesthesia of the site.
|
FALSE
|
|
TRUE OR FALSE:In general, skin biopsies are not performed as often as they should bein veterinary medicine
|
TRUE
|
|
List 3 unusual complications from a biopsy sample collection might include
|
minor hemorrhage infection and dissemination of neoplastic cells |
|
List 4 agents can cause inflammatory lesions in the skin?
|
bacteria fungi foreign bodies and parasites |
|
The most common skin biopsy punches areapproximately
|
4-6 mm
|
|
Taking a section of the liver would be:
|
incisional biopsy
|
|
T or F: The removal of a portion of the lesion is known as excisional biopsy
|
FALSE
|
|
True or False: The removal of a portion of the lesion is known as excisional biopsy
|
FALSE
|
|
Which of the following techniques minimizes pharyngeal contamination of the sample obtained?
|
Transtracheal
|
|
True or False: In general, skin biopsies are not performed as often as they should be in veterinary medicine.
|
TRUE
|
|
Which of the following organs can be easily aspirated?
|
Liver
|
|
What are two examples of discrete cells:
|
histiocytoma and transmissible venereal tumors
|
|
When sending biopsy samples in to the lab, all of the following arealways necessary
|
name of patientbreed of patient age of patient location of lesion
|
|
True or False: Nuclear criteria of malignancy are more reliable than cytoplasmic criteria for estimating malignant potential.
|
TRUE
|
|
Tumors can be classified into what 3 categories?
|
epithelial mesenchymal (spindle-cell) discrete round cell tumors |
|
Variable size and shape in cells of the same type is termed:
|
pleomorphism
|
|
True or False: A Mast Cell Tumor is an example of around or discreet cell tumor?
|
TRUE
|
|
True or False: Biopsy and aspiration are inter-changeable terms.
|
FALSE
|
|
The study of cells is known as
|
CYTOLOGY
|
|
A vaginal smear during this time would appear"clearer" showing a predominance of cornified cells, with no WBCs and decreasing RBC's
|
estrus
|
|
The first heat cycle experienced by the femaledog can occur anywhere from 6-24 months of age depending on the breed
|
TRUE
|
|
Ovulation usually occurs during the end of:
|
estrus
|
|
Female cats are seasonally polyestrus
|
TRUE
|
|
The mean duration of estrus in a cat is
|
8 days
|
|
True or False: Progesterone is the predominant hormone during proestrus.
|
FALSE
|
|
Vaginal epithelial cells can be classified into which of the following type:
|
basal cells paranasal cells intermediateintermeidate cells superficial cells |
|
The stage of the estrus cycle that is markedwith predominantly red blood cells is
|
proestrus
|
|
Estrogen is the predominant hormone during metestrus
|
FALSE
|
|
Through cytological examination of the vaginal smear, optimum breeding times can be managed.
|
FALSE
|
|
Which are included in the components of the immune system?
|
B-lymphocytes T-lymphocytes Macrophages |
|
The ELISA test for FeLV tests for exposure to the disease.
|
TRUE
|
|
Lymphocyte counts are a very crude estimate in evaluating a cell mediated response of the immune system.
|
TRUE
|
|
There is not presently a good test for FIP.
|
TRUE
|
|
Renal failure may depress red blood cell formation.
|
TRUE
|
|
Hemolytic anemia is the type of anemia that shows the most regenerative response.
|
TRUE
|
|
TRUE OR FALSE: The Monocyte is the body's first line of defense in infection.
|
FALSE
|
|
TRUE OR FALSE: Lymphocytes are the primary cellular components of the antibody producing system.
|
TRUE
|
|
True or False: When using serological test kits, it is important that the directions be followed carefully.
|
TRUE
|
|
Which of the following is an example of a coronavirus?
|
FIP
|
|
True or False: Animals in the recovery phase of an infectious disease is resistant to reinfection.
|
TRUE
|
|
The maternal immunity in young kittens does interfere with FeLV diagnostic tests.
|
FALSE
|
|
True or False: There is presntly no good test for FIP in cats
|
TRUE
|
|
FeLV is considered to be a CORE vaccine for cats.
|
FALSE
|
|
Neoplastic cells in the blood or bone marrow are significant in diagnosing
|
Leukemia
|
|
A group of bone marrow disorders, usually neoplastic, characterized by proliferation of the bone marrow cell lines
|
Myeloproliferative disorders
|
|
__________ are 0.5 to 2.0 µm angular blue grey particles, usually at the periphery of the cell.They represent aggregations of rough endoplasmic reticulum.
|
Doehle bodies
|
|
Name the RBC Maturation
|
Rubriblast Prorubricyte Rubricyte Metarubricyte polychromatophillic rubricyte mature erythrocyte |
|
Name 3 specific cell type tumors
|
(squamous cell, fibroblast, lymphoblast)
|
|
variation in cellmorphology within thesame population
|
Pleomorphism
|
|
Variation in size and shape of cells
|
anisokaryosis
|
|
Name 3 Routes of Metastasis
|
Hematagenous Lymphatic Implantation |
|
malignant tumors involving epithelial origin
|
Carcinomas
|
|
malignant tumors involving connective tissue origin
|
Sarcomas
|
|
Chemo for Transmissable Venereal Tumors
|
vincristine
|
|
Treatment of Lymphosarcoma -
|
steroids, cyclophosphamide, vincristine
|
|
Treatment for mast cell tumors
|
steroids
|
|
3 Main Categories of tumors
|
Round (Discrete) Cell Tumors Epithelial Tumors Mesenchymal (Connective |
|
Name the 4 Epithelial Tumors
|
Squamous Cell Basal Cell Adenomas Adenocarcinomas |
|
Name all 6 Spindle Cell Tumors (mesenchymal/connective)
|
Fibrosarcoma Osteoma Osteosarcomas Lipoma Hemangiosarcoma Sarcoma |
|
Name the sites for bone marrow collection
|
Dorsal iliac crest (wing of the ilium) Trochanteric fossa of proximal femur Proximal humerus Rib |
|
RBC Mature in approximately ____ days and then circulate for _______ days depending on the species.
|
4-5 100-120 |
|
Granulocytes take approximately _____ days to mature and then only have a half life of @ ___ hours, before they Sequester into the tissues
|
5-7 12 |
|
____ Lymphocytes are associated with the Thymus and are involved with cellular immunity.
|
T
|
|
____ Lymphocytes are associated with the Bursa of Fabricious and are involved with humoral immunity, specifically the production of immunoglobulins.
|
B
|
|
Megakaryocyte maturation takes hours and then the platelets circulate ______ days.
|
6-10
|
|
Term that means no bone marrow development
|
Aplastic
|
|
Term that means ineffective (common cats) - an alteration in size, shape and organization in adult cells, this indicates ineffective bone marrow development
|
Dysplastic
|
|
Term that means Abnormal development of cells, any new, abnormal growth, one where cell multiplication is uncontrolled.
|
Neoplastic
|
|
________ cells have > 75% cellularity, abnormal increase of a tissue or organ caused by formation of normal new cells. Indicates greater then 75% cellularity in the bone marrow
|
hyperpastic
|
|
_________ cells have < 25% cellularityaplastic- Having no tendency to develop into new tissue, no bone marrow development, incomplete or underdevlopment of a organ or tissue. Indicates less then 25% in the bone marrow
|
hypoplastic
|
|
____________ conditions- abnormal proliferation of bone marrow constituates.
|
Myeloproliferative
|
|
________ leukemia is a leukemia associated with hyperplasia and over development of lympoid tissue.
|
Lymphocytic
|
|
___________ disease- transfer of cells/ disease/ cancer from one organ to another.
|
Metastatic neoplastic
|
|
____________- abnormal increase of erythroid cells.
|
Erythroid hyperplasia
|
|
_______________ : The study of diseased tissue
|
Histopathology
|
|
____________ : The study of diseased cells
|
Cytopathology
|
|
Divide malignant tumors into three categories
|
Epithelial Connective Tissue Round Cell |
|
__________________ They entire lesion is removed. Usually sent off for analysis, this is up to the owner.
|
Excisional
|
|
____________ Cut into the lesion and remove a portion of the lesion.usually done when the lesion is large and removal may compromise.
|
Incisional
|
|
____________ Cytology includes Skin Scrapings, Impression Smears. KOH Preps, Vaginal Cytology, and Body Fluids
|
Exfoliative
|
|
______________ - an abnormal collection of normal fluid. Have low total cell counts(> 500/ul) Watery fluid
|
Transudates
|
|
___________- an abnormal collection of abnormalfluidnHave high total cell counts(<500/ul) usualy Thick fluid
|
Exudates
|
|
__________ Greater than 70% nutrophils
|
Acute
|
|
______ ________ 50-70% are nutrophils and 30-50% are macrophages, a few eosinophils may be present.
|
Chronic Active
|
|
________ Greater than 50% of the cells are macrophages
|
Chronic
|
|
___________ term used when giant or epitheliod cells are present
|
Granulatomous
|
|
__________ are foreign substances, usually proteins,that can be viral, bacterial, or fungal.
|
Antigens
|
|
____________ are responsible for the recognition and elimination or antigens. (Ab) In-responsive to antigens.
|
Antibodies
|
|
__________ cells - include macrophages, neutrophils
|
Accessory
|
|
__________________ is the separation of plasma proteins by molecular weight in an electric field.
|
Electrophoresisois
|
|
What are the three methods of biopsy that are used for bone marrow collection?
|
aspiration core incisional biopsy |
|
___________ will frequently have a specific gravity less than 1.017
|
Transudates
|
|
_______have specific gravity more than 1.017
|
Exudates
|
|
Transudates are frequently:
|
Clear
|
|
___________ are frequently cloudy
|
Exudates
|
|
____________________ an example of a modified transudate which shares some of the characteristics of both transudates and exudates.
|
F I P (Feline Infectious Peritonitis) is
|
|
The preferred site for obtaining a CSF tap in a dog is the __________________
|
cerebellomedullary cistern
|
|
When performing a transtracheal wash, one should direct the catheter needle through the _______________________
|
cricothyroid membrane.
|
|
How much fluid should normally be collected when performing a spinal tap?
|
2cc
|
|
____________- is an increase in the size of an organ caused by an increase in the size of the cells rather than the number of cells.
|
hypertrophy
|
|
____________- an increase in the number of cells of a body part.
|
hyperplasia
|
|
Purulent or suppurative inflammatory responses are characterized by _____ neutrophils.
|
> 85%
|
|
The most common tumors in the cat are associated with which system?
|
hemolymphatic system
|
|
What is a commonly used drug that can be used in cancer therapy?
|
prednisolone
|
|
____________ and __________ are examples of chemotherapeutic drugs that are used in veterinary medicine to treat cancer.
|
Cyclophosphamide Chorambucil |
|
Myelosuppressive drugs should not be used if the WBC count drops below ______ cells/mm3.
|
4,000
|
|
Toxicities to chemotherapy are seen most commonly in rapidly dividing tissues, such as ______, _________, and ________
|
bone marrow hair follicles and intestines. |
|
_________ tumors are commonly referred to as sarcoma tumorsc
|
Spindle cell
|
|
__________ may last 4 to 13 days, with an average of 9 days.
|
Proestrus
|
|
____________ usually lasts 4 to 13 days, with an average of 9 days. No neutrophils will be present.
|
Estrus
|
|
_______________ may last 2-3 months. Erythrocytes are generally absent.
|
Metestrus
|
|
How often should a bitch be bred during estrus?
|
Every fourth day throughout the period
|
|
Which 3 neoplastic cells may be seen on a vaginal cytology?
|
Transitional-cell carcinoma squamous-cell carcinoma vaginal lymphosarcomas |
|
What are some disorders which may result from the malfunctioning of the immune system?
|
allergies, immunodeficiency, neoplasia, or autoimmune diseases
|
|
What are the two immune systems at work in vertebrate species?
|
innate immune system and adaptive immune system
|
|
What are the 2 components of the adaptive immune system?
|
humoral immune system and cell-mediated immune system
|
|
__________ is abnormalities in serum immunoglobulins characterized by increased levels
|
Gammopathies
|
|
In AIHA affected cats, what are the common underlying systemic diseases seen?
|
FeLV, myeloproliferative disease, Hemobartonella felis
|
|
What does the Coombs Test detect the presence of, and what disease does it confirm diagnosis?
|
AIHA |
|
List the 3 types of enzyme immuno assays.
|
sandwich assay -for antigens indirect assay-- for antibodies competitive assay -for drugs and hormones |
|
__________ is a common skin disease of cats caused by fungal infections with Microsporum canis, M. gypseum or Trichophyton mentagrophytes.
|
Ringworm
|
|
The five primary classes of immunoglobulins are ________________________ These are distinguished by the type of heavy chain found in the molecule.
|
IgG, IgM, IgA, IgD and IgE.
|
|
____________ tests are used to demonstrate the presence of antibodies against a specific antigen in serum.
|
Indirect fluorescent-antibody
|
|
What enzyme is responsible for breaking down starches?
|
Amylase
|
|
Which of the following is a test of the liver that is not anenzyme?
|
Bile Acids
|
|
What is a normal blood glucose?
|
100 mg/dl
|
|
The term for too much sodium is
|
Hypernatremia
|
|
What enzyme is responsible for breaking down protein?
|
Trypsin
|
|
What is the old term for ALT?
|
SGPT
|
|
What enzyme is responsible for breaking down fats?
|
Lipase
|
|
When the pH of the blood drops below the normal 7.3 range,then the animal is thought to be in
|
acidosis.
|
|
Increases of what electrolyte may be associated withkidney disease?
|
K
|
|
Carbonic acid breaks down to which of the following?
|
H, H20, HC03, & CO2
|
|
An increase of what electrolyte is associated with renaldisease?
|
K
|
|
Blood gasses are measured using what type of vacutainer?
|
HEPARIN
|
|
Increases of what electrolyte may be associated withmetastatic or neoplastic disease?
|
Ca
|
|
What hormone decreases blood sugar?
|
INSULIN
|
|
Calcium concentrations generally are inversely related toinorganic phosphorus.
|
TRUE
|
|
Serology is the branch of science primarily involved with
|
antibodies or antigens
|
|
Renal threshold of glucose is approximately
|
175 mg/dl
|
|
The adrenal gland causes the production of
|
Cortisol
|
|
Which of the following tests are used in the diagnosis of hyperadrenocorticism
|
Dexamethasone suppression and ACTH stimulation test
|
|
Which of the following tests is for the liver
|
ALT
|
|
The opposite of Cushing's Disease is
|
Hypoadrenocorticism
|
|
Hypothyroidism is NOT associated with pu/pd
|
TRUE
|
|
T4 IS PRODUCED BY THE
|
THYROID
|
|
TSH is produced in the
|
pituitary gland
|
|
In reference to specimen collection the Vagina is NOT considered a closed body area
|
TRUE
|
|
When obtaining a sample for evaluation, your biggest concern is
|
Avoiding contamination from other tissues, secretions, or foreign substances
|
|
Which stain is most useful when differentiating the bacterial species present on a sample smear
|
Gram stain
|
|
It is ok to leave anaerobic samples out overnight, as long as you package and transport them to a laboratory facility first thing in the morning
|
FALSE
|
|
To reduce the incidence of nosocomial infections, veterinary hospitals should only use disinfectants that:
|
Are registered by the E.P.A.
|
|
Nosocomial infections are most often seen in
|
Large, referral practices or teaching institutions
|
|
Osha stands for Occupational Safety and Hazard Administration
|
FALSE
|
|
Gram positive cocci will appear what color on a well gram stained slide
|
PURPLE
|
|
In the gram stain procedure, the safarin counterstain is
|
The last solution used in the procedure, before rinsing.
|
|
On stained smears, bacteria are best identified on:
|
100x oil Immersion objective.
|
|
Which of the following groups most frequently requires routine anti microbial testing? |
Gram-negative bacteria |
|
The MIC in susceptibility testing is defined as |
The lowest concentration of antimicrobial that macroscopically inhibigts growth of the organism |
|
Antimicrobial susceptibility testing is performed because |
Some microorganisms are resistant to a given antibiotic |
|
If Anthrax is suspected you should |
Refrain from opening body cavities. Draw blood for diagnosis, preferably from an ear vein |
|
How many mls of blood should be obtained for a blood culture |
5-10 ml's |
|
True or False: Pseudomonas is a gram-positive bacterial pathogen |
FALSE it is a gram-negative |
|
Cat scratch fever is caused by the following bacterial organism |
Bartonella |
|
True or False: Always use a pure culture of bacteria for inoculation for antimicrobial susceptibility testing using agar diffusion test |
TRUE |
|
Within the Bacterial Growth Curve, which phase includes as many bacteria multiplying as there are dying? |
stationary phase |
|
There are three ways in which bacteria can modify their genetic make-up through sexual methods. This is known as what? |
recombination |
|
Name 3 examples of a mechanism for host resistance. |
Mucous membranes Phagocytosis Lymph tissue |
|
You should allow inoculated primary-isolation media to incubate for how long before issuing a "no growth" final report |
72 hours |
|
A Catalase test differentiates what from what. |
staph + and strep – |
|
In this type of hemolysis you will see, partial clearing and greening of the agar around the colonies. |
Alpha hemolysis |
|
The four quadrant streaking method of solid-media inoculation of plates is specifically designed to |
dilute the specimen (in a way that isolated colonies develop, each representing a single bacterial organism) |
|
Lack of color or a color change surrounding colonies on the normal red blood- agar plates is caused by: |
Hemolysis |
|
Disease caused by dermatophytes is also known as: |
ringworm |
|
Systemic Mycoses are important to us because: |
they can be zoonotic |
|
The following is a systemic mycosis commonly found in cats and presents kennel cough like symptoms in dogs. |
coccidiomycosis |
|
Name 3 types of yeast |
Malassezia Candida Cryptococcus neoformans |
|
The following is a pathogen that usually involves the mucous membranes or wet areas of the body. |
Candida albicans |
|
Name an example of a coronavirus? |
FIP |
|
Animals in the recovery phase of an infectious disease is resistent to reinfection |
TRUE |
|
The mean age of puberty is
|
10-12 months
|
|
Name the four stages of the estrous cycle
|
Proestrus Estrus Metestrus (diestrus) Anestrus |
|
What stage of the estrus cycle is this photo
|
PROESTRUS Note the parabasal cells, intermediate cells, and superficial cells. Many erythrocytes but only small amount of neutrophils |
|
What stage of the estrus cycle is this photo
|
LATE PROESTRUS
|
|
The average length of estrus is _____ days
|
9 days
|
|
What stage of the estrus cycle is this photo
|
ESTRUS notate the cornified superficial cells
|
|
What stage of the estrus cycle is this photo
|
Metestrus: note the decline in cornified cells, reappearance of intermediate, and parabasal cells
|
|
What stage of the estrus cycle is this photo
|
Anestrus: Superficial cells are absent or in small numbers neutrophils may be present or absent
|
|
Epithelial Tumors include these 4 classifications
|
Squamous Cell
Adenomas
|
|
What are the 3 main categories of tumors
|
Round (discrete) cell tumors Epithelial Tumors Mesenchymal (Connective) |
|
Spindle cell tumors aka mesenchymal/connective tumors include
|
Fibrosarcoma Osteoma
Lipoma
|
|
Round cell tumors aka Discreet tumors include
|
Mast Cell
Histiocytoma (can be confused with TVT) |
|
______ biopsy is the removal of the entire lesion
|
Exisional
|
|
______ biopsy is the removal of a portion of the lesion
|
Incisional
|
|
_____ is the most abundant of the immunoglobulins it plays a major role in humoral immunity
|
IgG
|
|
This immunoglobulin prevents the attachment of pathogens to the mucosal surfaces. This includes the intestinal, respiratory and urogenital tracts.
|
IgA
|
|
This immunoglobulin has the largest antibody, the first to respond to an antigen
|
IgM
|
|
This immunoglobulin is found in allergic and parasitized patients
|
IgE
|
|
Name two autoimmune diseases
|
AIHA Demodex |
|
______ is considered a Immunoproliferative disease
|
Felv
|
|
Anaerobic bacteria needs to be protected from __________ and must be obtained with a sterile syringe with a small needle
|
Oxygen
|
|
_______ are obligate intercellular parasites and they cannot live or function outside a living cell
|
Viruses
|
|
_________ response includes phagocytic response, fever, increased blood flow, pain, swelling
|
Inflammatory
|
|
Protein substances released from intact or lysed bacteria that cause antigenic reactions
|
Exotoxins
|
|
Weaker, less antigenic, released from intact or lysed gram negative bacteria
|
Endotoxins
|
|
_________ is a extracellular enzyme produced by staphylococcus aureus, clots fibrin and protects bacterium
|
Coagulase
|
|
__________ is an extracellular enzyme produced by many different bacteria, breaks down tissues to aid in spread of infections
|
Hyaluronidase
|
|
__________ is an extracellular enzyme produced by Clostridia, breaks down tissue collagen to spread infection
|
Collagenase
|
|
_________ __________ is the common cause of mastitis in cattle and other superficial infections in cattle, sheep, goats, birds, rabbits, turkeys and humans
|
Staph. Aureus
|
|
Common organisms seen in the horse that occur singly, in pairs or in short chains.
|
Streptococci
|
|
_________ ___________ is the most pathogenic bacteria for both animals and humans.
|
Bacillus anthracis
|
|
Anaerobic gram positive rods include _____ which has many pathogenic species
|
Clostridium
|
|
Coliforms are gram negative rods which live in the intestinal tracts of animals and humans name the 3 most common species
|
E. Coli Salmonella Pseudomonas |
|
_______ stain as short, fat, gram negative rods and cannot be told apart by gram stain only biochemical testing
|
Coliforms
|
|
A common inhabitant in dogs and cats mouths and is the most commonly isolated bacteria from infected dog and cat bites
|
Pasteurella
|
|
______ are gram negative rods and have a predilection for the reticuloendothelial system and the reproductive tract.
|
Brucella
|
|
______ species of bacteria frequently isolated from the urinary tract
|
Proteus
|
|
__________ is a species of bacteria found in wounds and ears producing a yellow-green discharge with a distinctive odor.
|
Psudomonas
|
|
Rocky mountain spotted fever is caused by this disease transmitted by ticks
|
Rickettsia
|
|
Medical term for Cat Scratch fever
|
Bartonella
|
|
Tiny bacteria with no cell walls hard to stain and see microscopically
|
Mycoplasma
|
|
Smallest and simplest microbes that cannot reproduce or maintain their functions outside of living cells
|
Viruses
|
|
______ is a route of transmission of an infection by respiratory route or ingestion of contaminated food or liquids.
|
Indirect
|
|
_______ test is a secondary test that differentiates Staph (+) from Strep (-)
|
Catalase
|
|
______ test indicates a positive reaction on by causing a purple color to appear on a cotton swab.
|
Oxidase
|
|
Name three types of hemolysis on agar
|
Alpha hemolysis Beta hemolysis Gamma hemolysis |
|
_______ hemolysis cause partial clearing and greening of the agar around the colonies
|
Alpha
|
|
_______ hemolysis causes no hemolysis, no clearing or alteration in the color of blood agar surrounding the colonies
|
Gamma
|
|
______ hemolysis causes a complete clearing around the colonies meaning the red blood cells in the blood agar have been completely dissolved.
|
Beta
|
|
______ is the lowest concentration of a specific antibiotic that will inhibit the growth of a specific bacteria.
|
Minimum inhibitory concentration
|
|
A selective media that was developed to attract growth for gram negative rods, these include ______ and _____ agars.
|
MacConkey or EBM agar
|
|
______ agar only allows Gram positive organisms to grow. |
Columbia agar
|
|
This agar is used for microbiological growth for antibiotic susceptibility testing.
|
Mueller-Hinton agar
|
|
_____ the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis.
|
Pyknosis
|
|
M:E ratio is considered normal at ___
|
1.0
|
|
M:E ratio is considered decreased when the wbcs are less than
|
0.5
|
|
M:E ratio is considered when the wbc is increased when greater than
|
2.0
|
|
_____ take 5-7 days to mature. Live an average of 12 hours. Sequester in the tissues and attracted to sites of inflammation.
|
Granulocytes
|
|
____ take 4-5 days to mature and are in duration for 100-120 days.
|
RBC's
|
|
________ live up to 6-10 days and give rise to platelets
|
Megakaryocytes
|
|
This type of aspiration includes sites from the dorsal iliac crest, trochanteric fossa, proximal humerus and the rib.
|
Bone biopsy aspiration
|
|
Name the WBC maturation series
|
Myeloblast Promyelocyte Myelocyte Metamyelocyte Band cell Segmented neutrophil |
|
___________ is what we use to measure the white cell (myeloid) precursors as compared to the red cell (erythroid) precursors
|
M : E Ratio
|
|
_______ - means no bone marrow development
|
Aplastic
|
|
_______ means ineffective (common cats) - an alteration in size, shape and organization in adult cells, this indicates ineffective bone marrow development |
Dysplastic
|
|
_______ means Abnormal development of cells, any new, abnormal growth, one where cell multiplication is uncontrolled.
|
Neoplastic
|
|
_________ means > 75% cellularity, abnormal increase of a tissue or organ caused by formation of normal new cells. Indicates greater then 75% cellularity in the bone marrow
|
hyperplastic
|
|
_________ means < 25% cellularityaplastic- Having no tendency to develop into new tissue, no bone marrow development, incomplete or underdevlopment of a organ or tissue. Indicates less then 25% in the bone marrow
|
hypoplastic
|
|
What are the two sites of choice for collection in both the dog and cat?
|
iliac crest and trochanteric fossa
|
|
Generally we think of _______ _________ as being characterized with 70% or greater neutrophils.
|
acute inflammation
|
|
Causes of __________ include ruptured pyometra, peritonitis and penetrating bite wound into the abdomen or thoracic cavities.
|
exudates
|
|
Causes of _________ include congestive heart failure, protein losing nephropathy and hepatic insufficiency.
|
transudates
|
|
The preferred site for obtaining a CSF tap in a dog is the
|
Cerebellomedullary cistern
|
|
How long should animals be observed following a spinal tap for signs of infection?
|
5-7 days
|
|
he most common tumors in the cat are associated with which system?
|
hemolymphatic system
|
|
Malignant tumors involving epithelial cells are called __________
|
Carcinomas
|
|
malignant tumors that involve connective tumors are known as
|
SARCOMAS
|
|
What are the three primary pancreatic enzymes?
|
Trypsin, Amylase, and Lipase
|
|
What are the most commonly assayed plasma proteins?
|
Total protein, albumin, globulins, and fibrinogen.
|
|
What is hyperadrenocorticism treated with?
|
Lysodren
|
|
TSH comes from where?
|
Pituitary gland
|
|
The normal blood sugar of a dog is
|
80-120 mg/dl
|
|
__________ are catalase- positive cocci that occur in grapelike clusters.
|
Staphylococcus spp
|
|
__________ are catalase-negative cocci that occur singly, in pairs, or in short chains.
|
Streptococcus spp.
|
|
How long should you let your culture media incubate before a final “no growth” report is issued? ( for most bacterial species)
|
72 hours
|
|
Which systemic mycoses is most frequently associated with pigeon droppings?
|
Cryptococcus neoformans
|
|
The study of diseased cells is called |
cytolopathology |
|
______________________ is an example of a modified transudate which shares some of the characteristics of both transudates and exudates. |
F I P (Feline Infectious Peritonitis) |
|
What two internal organs can be aspirated for evaluation |
Liver and Kidneys |
|
_____________ increase in the size of the organ caused by an increase size in cells |
Hypertrophy |
|
___________ increase of the number of cells in a body part |
hyperplasia |
|
Chronic inflammatory are characterized by greater than _____ macrophages |
50% |
|
Purulent or suppurative inflammatory response are characterized by greater than _____ neutrophils |
85% |
|
_______ and ______ are examples of chemotherapeutic drugs that are used in veterinary medicine to treat cancer. |
Cyclophosphamide Chorambucil |
|
Myelosuppressive drugs should not be used if the WBC count drops below _______ cells/mm3. |
4,000 |
|
Toxicities to chemotherapy are seen most commonly in rapidly dividing tissues, such as ______, ________, and _________ . |
bone marrow hair follicles and intestines |
|
Malignant tumors involving epithelial cells are called ________________ |
CARCINOMAS |
|
Whereas malignant tumors that involve connective tumors are known as |
SARCOMAS |
|
Examples of connective tissue include __________, ___________, and ___________. |
BONE CARTILAGE BLOOD |
|
T or F: During Anestrus a cytology will show predominately noncornified squamous epithelial cells, and some neutrophils. No erythrocytes will be seen. |
TRUE |
|
T or F: During Proestrus a cytology will show cornified squamous epithelial cells. Not many neutrophils will be seen, as they are replaced with erythrocytes. |
TRUE |
|
T or F: During Estrus a cytology will reveal cornified epithelial cells and erythrocytes. No neutrophils will be present. |
TRUE |
|
Give two examples of dermatophytes. |
Microsporum and Trichophyton |
|
Which agar is the most commonly used medium for fungal cultures? |
Sabourand dextrose agar |
|
DTM cultures should be observed for growth and color for how long before reporting a “negative” result. |
aprox. 15 days. |