Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/9

Click to flip

9 Cards in this Set

  • Front
  • Back
etiology of asthma
mucus plug, edema, bronchoconstriction, cellular infiltration
cardinal feature of most athmatics
non specific bronchial hyperreactivity
mechanism of beta agonist in bronchodilation
activate adenylate cyclase => elevate cAMP levels
mechanism of theophylline
- phosphodiesterase inhibitor
- adenosine antagonist
ipratropium mechanism of action
antimuscarinic => bronchodilation

antimuscarinic and b2 agonist are equal in COPD patient, but b2>antimuscarinics for asthma
cromolyn
- poorly absorbed across mucosal membranes
- prevent late asthmatic response to inhaled allergen
- does not affect cAMP
- inhibit mast cell release in response to non-specific stimuli.. acts directly on mast cell membranes
mechanism of corticosteroids (beclamethasone)
- no direct bronchodilator effect
- affect secretion of mediators and inflammatory component
zileuton
inhibits leukotriene formation by inhibiting 5-lipoxygenase
zafirlukast
montelukast
block binding of LTD4 to its receptors