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108 Cards in this Set

  • Front
  • Back
(E transcription) Polymerase I makes
rRNA
(E transcription) Polymerase II makes
mRNA
(E transcription) Polymerase III makes
tRNA
mRNA processing of eukaryotic RNA
5'-cap
Poly A tail
Introns removed and exons spliced together
What direction is DNA new strand made in DNA replication
5' --> 3'
(P replication) Polymerase III job
Replicates both parental strands
Proofreads
3' exonuclease
(P replication) Polymerase I job
Removes primer and fills in gaps w/ DNA (5' exonuclease)
(P replication) Polymerase II job
DNA repair (3' exonuclease)
(E replication) delta polymerase
Makes leading strand
(No proofreading, no exonuclease)
(E replication) alpha polymerase
Makes lagging strand
Primase activity
(E replication) Beta & epsilon polymerase
DNA repair (3' exonuclease)
(E replication) gamma polymerase
mitochondrial DNA polymerase
What tissue does adenomas and carcinomas arise from
Ecto- or endoderm
What tissues does sarcomas and fibromas arise from
Mesoderm
Ectoderm becomes what
Neural tube --> CNS
Neural crest --> PNS
Placodes --> sensory
Surface epithelium
Mesoderm becomes what
Somites --> muscles, vertebral column
CT
lymphatics
blood cells
Endoderm becomes what
epithelium of GI
Liver
Pancreas
Thymus
Thyroid
Umbilical cord contains what?
2 arteries (deoxygenated blood)
1 vein (oxygenated blood from placenta to baby)
Umbilical arteries become
Medial umbilical lig
Urachus becomes
median umbilical lig
Umbilical vein becomes
Round lig
Ductus venosus becomes
venous lig
Ductus arteriosus becomes
Ligamentum arteriosus
Yolk sac becomes
Meckel's diverticulum (2-2-2)

2% of population
w/i 2 feet ileocecal jnct
2 cm long
1st brachial arch forms
Malleus, incus
M. of mastication
Facial a.
CN V3
2nd brachial arch forms
Stapes, Styloid, lesser horns of hyoid
M. facial expression
Ext. carotid a.
CN VII
3rd brachial arch forms
Body of hyoid
Stylopharyngeal m
Internal carotid artery
CN IX
4th brachial arch forms
Larynx
Pharyngeal m.
CN X
Pharyngeal clefts form
I - external auditory meatus
II-IV - cervical sinus (disappears or becomes cervical cyst)
Pharyngeal pouch I forms
Tympanic cavity
Eustachian tube
Pharyngeal pouch II forms
Palatine tonsil
Pharyngeal pouch III forms
Ventral - thymus
Dorsal - Inferior parathyroids
Pharyngeal pouch IV forms
Dorsal - superior parathyroids
Pharyngeal pouch V forms
Ultimobranchial body --> parafollicular C cells of thyroid
Mesonephric duct becomes ____ which does what?
Wolff
male - epididymis, vas deferens

(disappears in F)
Paramesonephric duct becomes ____ which does what?
Muller
(M - diappears)
F - fallopian tubes, uterus, vagina down to hymen
What causes male differentiation
Wolff is sustained by Testosterone (Leydig cells)
Muller is suppressed by MIF glycoprotein (Sertoli cells)
What becomes the kidneys
Metanephros

(pronephros & mesonephros disappears)
What enters via optic canal
Optic n
Ophthalmic a.
What enters via superior orbital fissure
CN III, IV, V (ophthalmic), VI
SNS
Ophthalmic v.v.
What enters via foramen rotundum
CN V (maxillary)
What enters via foramen ovale
CN V (mandibular)
Accessory meningeal a.
What enters via foramen spinosum
Middle meningeal a.
What enters via foramen magnum
SC
Accessory n.
Vertebral a.a.
Spinal a.a.
What enters via jugular foramen
CN IX, X, XI
Internal jugular v.
What enters via hypoglossal canal
CN XII
What enters via internal auditory meatus
CN VII, VIII
Labyrinthine a.
If you have an abducens paralysis, clinical?
Cant abduct eye to affected side
Diplopia
If you have a trochlear paralysis, clinical?
Slight vertical double image
Pt compensates by tilting head
Mneumonic for EOM
LR 6 SO 4

Lateral rectus - CN VI
Superior oblique - CN IV
All the rest CN III
Which way does superior rectus make you look
Up and nasal
Which way does inferior oblique make you look
Up and temporal
Which way does inferior rectus make you look
Down and nasal
Which way does superior oblique make you look
Down and temporal
What eye muscle causes mydriasis, innervation
(dilation)
Dilator pupillae
Sympathetic
What eye muscle causes miosis, innervation
(constriction)
Sphincter pupillae
Parasympathetic
What eye muscle is responsible for accommodation
Ciliary muscle
Parasympathetic

(contract ciliary m., relaxes suspensory lig, allows lens to turn into globular shape for near vision)
What eye muscles raises lid, innervation
Levator palpebrae super. - CN III
Muller's m. - SNS
Clinical Horner's syndrome
Miosis
Ptosis
Red & dry facial skin on affected side
Tongue motor - muscle, action, innervation
Genioglossue - out
Styloglossus - in & up
Hyoglossus - down

(all via CN XII)
Damage to hypoglossal n. - clinical
Deviates toward side of damage
Tongue sensation anterior 2/3
Taste - VII
Touch & Temp - V3
Tongue sensation posterior 1/3
CN IX

(taste & touch)
Function of lat. pterygoid, digastric, geniohyoid m.
Open mouth
Function of masseter, (med. pterygoid, temporalis)
Close mouth
Function of lateral pterygoid
Protrudes mouth
Lateral dysplacement
Function of temporalis
Retracts mandible
Innervation of post. cricoarytenoid, lat. cricoaryteniod, thyroaryteniod
Recurrent n.
Function of
Posterior cricoarytenoid
Open glottis
Function of
Lateral cricoaryteniod
Closes glottis
Function of
Thyroarytenoid
Relaxes vocal cords
Function of & innervation of
Cricothyroid
Tightens vocal cords
Superior laryngeal n
What does the L laryngeal n. wrap around
Aortic arch
What does the R laryngeal n. wrap around
R subclavian a.
Sensation above glottis
Superior laryngeal n.

(important in cough reflex)
Sensation below glottis
Recurrent n.

(important in cough reflex)
Main shoulder muscle that adducts & innervation
Pectoralis major
C5-T1
Main shoulder muscle that abducts &
innervation
1st 60 degrees - Deltoid
Then - Sarratus anterior
Long thoracic n.
Main shoulder muscle that anteverts & innervation
Deltoid
Axillary
Main shoulder muscle that retroverts & innervation
Teres major
Subscapular n.
Main shoulder m. outward rotation & innervation
Infraspinatus
Suprscapular n.
Main shoulder m. inward rotation & innervation
Subscapularis
Subscapular n.
What is the problem when pt presents w/ "scapular winging"?
Serratus anterior m. paralysis
Damage to long thoracic n.
Muscle that make up the rotator cuff
Supraspinatus
Infraspinatus
Teres minor
Subscapularis
Spinal segments that make up upper trunk of brachial plexus & terminal n.
C5-6
Musculocutaneous n.
Spinal segments that make up middle trunk of brachial plexus & terminal n.
C7
Axillary n. & radial n. (posterior cord)
Median n.
Spinal segments that make up lower trunk of brachial plexus & terminal n.
Ulnar n.
Clinical s/s & cause of upper brachial plexus injury
"waiter tip" (arm hangs in medial rotation)

forceful separation of neck & shoulder, motorcycle accident, football tackling
Clinical s/s & cause of posterior cord brachial plexus injury
"wrist drop"
Radial n. injury
Compression by too long crutches
Clinical s/s & cause of lower brachial plexus injury
"Claw hand"
Ulnar n. injury
Forceful pull of arm/shoulders (birth)
"wrist drop"
No tricep reflex
Sensory loss: posterior arm, dorsal hand
Radial n. injury
No F thumb, index finger, middle finger
No thumb opposition
Thenar atrophy
Sensory loss: radial 2 1/2 fingers (palms & tips)
Median n. injury
"Claw hand"
No F 4th or 5th finger
Apothenar atrophy
Sensory loss: Ulnar 1 1/2 fingers (palms & tips)
Ulnar n. injury
No elbow F
No supination
No bicep reflex
Sensory loss: extensor aspect of forearm
Musculocutaneous n. injury
What n. is commonly injured with a humerus fx
Radial n.
Muscle for elbow F & innervation
Biceps brachii
MC n.
Muscle for elbow E & innervation
Triceps brachii
Radial n.
Muscle for elbow supination & innervation
Biceps brachii
MC n.
Muscle for elbow pronation & innervation
Pronator teres
Median n.
Cause of "tennis elbow"
Lateral epidondylitis
(origen of the extensor muscles)
Hip m. outward rotation & innervation
Gluteus maximus
Inferior gluteal n.
Hip m. inward rotation & innervation
Gluteus medius/minimus
Superior gluteal n.
Hip m. E & innervation
Gluteus maximus
Inferior gluteal n.
Hip m. F & innervation
Iliopsoas
Femoral n.
Hip m. abduction & innervation
Gluteus medius
Superior gluteal n.
Hip m. adduction & innervation
Adductor magnus/minimus
Obturator n.
Who is at risk for femoral neck fx? Complication?
Elderly women (osteoporosis)
Risk of avascular necrosis of femoral head
What position does a femoral neck fx typically occur in?
Abduction & external rotation