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22 Cards in this Set

  • Front
  • Back
Drugs that Inhibit P450
"Some Pharmaceutical Classes Inhibit Drug Catabolism"
Sulfonamides
Phenylbutazone
Chloramphenicol
Isoniazid
Cimetidine
Dicumerol
Bad drug interactions
-AG & Loops
-MAOIs & SSRIs
-MAOIs & TCAs
-Antiarrythmics & FQs
-Cation-containing durgs/citric acid & FQ
-Alcohol/rifampin & isoniazide
-Nephrotoxicity & ototoxicity
-Serotonin syndrome
-Serotonin syndrome or severe SNS activation
-prolonged QT
-severe impairment of FQ absorption
-liver damage --> liver failure
Drugs that cause HTN crisis
(malignant HTN & tachycardia)
MAOI
TCAs
Drug that causes NAION
(non-arteritic anterior ischemic optic neuropathy)
PDE-5 inhibitors
Drugs that cause neurotube defects
Carbamazepine
Valporic Acid
Drugs that cause ototoxicity
AG
PDE-5 inhibitors (permanent vision & HL)
Drugs that cause drug-induced lupus
Hydralazine
Procainamide
Drug causes G6PD exacerbation
Sulfa
Primaquine
Drugs that Induce P450
"One Pharmaceutical Brings About Rapid Liver Metabolism"
OCP
Phenytoin
Barbiturates
Alcohol
Rifampin
Levodopa
Methadone
Drugs that are easily displaced from albumin
"Serum Proteins Can Spew"
Sulfonamides
Phenylbutazone
Coumadin
Sulfonylureas
Drugs that compete at renal trasporters
"Some Pharmaceuticals Plus Urate Stop Transporters"
Sulfonamides
Probenecid
Penicillin
Urate
Salicylates
Thiazides
Drugs that cause Bone Marrow Toxicity
Most chemotherapeutic agents
Chloramphenicol
Ganciclovir
Zidovudine (AZT)
Interferon
Flucytosine
Carbamazepine
Drugs that cause Hepatotoxicity
All imidazoles
Interferon
Nevirapine
all HMG CoA inhibitors
Valportic Acid
Isoniazid
Drugs that cause nephrotoxicity
AG
Foscarnet
Cidofovir
NSAIDs
Cyclosporin
Amphotericin
Drug that causes tendon rupture
Quinolones
Drugs that cause DVTs
Raloxifene
Tamoxifen
Estrogen/Progesterone
Drugs that cause orthostatic hypotension
All alpha blockers
most TCAs
Drugs that cause serotonin syndrome
MAOIs
SSRIs
Decongestants
TCAs
SNRIs
Drug that causes cutaneous flushing
Niacin
Drug that causes seizures
Meperidine
Drug that causes malignant hyperthermia
Halothane
Drug that causes Ebstein's anomaly
Lithium