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40 Cards in this Set

  • Front
  • Back

Nucleus

Contains genetic material which controls the activities of the cell

Cyptoplasm

most chemical processes take place here, controlled by enzymes

Cell Membrane

Controls movement of substances into and out of the cell

Mitochondria

Most energy is released by respiration here



Site of Respiration, ATP production

Ribosomes

Protein synthesis happens here

Golgi Apparatus

Processes and packages new lipids and proteins. It also makes lysosomes

Rough Endolplasmic Reticulum

Folds and processes proteins that have been made at the ribosomes

Smooth Endoplasmic Reticulum

Synthesizes and processes lipids

Types of Diffusion

Diffusion



Osmosis



Active Transport

Diffusion

Movement of particles from a high concentration to a low concentration down a concentration gradient

Osmosis

Net diffusion of particles from a solution with a high water potential to a solution with a low water potential down a concentration gradient

Active Transport

Uses Energy to move molecules and ions against a concentration gradient

Facillitated Diffusion

Some larger molecules (eg. Amino Acids, Glucose) and ions can't diffuse directly through the phospholipid bilayer of the cell membrane.



Insted they diffuse through carrier proteins or protein channels in the cell membrane

Carrier Proteins

Move large molecules into or out of the cell.



1. Large molecule attatches itself to the carrier protein



2. Then the protein changes shape



3. This releases the molecules on to the opposite side of the membrane

Protein Channels

Form pores in the membranes for charged particles to diffuse through



Different protein channels facillitate the diffusion of different charged particles

Properties of Fluid Plasma Membrane

1. Membrane is a good barrier against most water soluble molecules



2. The membrane contorls what enters and leaves



3. The membrane allows cell communication



4. The membrane allows cell recognition



5. The membrane is fluid

Prokaryotic Cell

Single celled organisms

Eukaroytic Cell

Multi cellular organism with specialised organelle inside

Enzymes

They are biological catalysts, they speed up the reaction without being used up



They work best at the optimum temperature of 37C



They have an optimum pH which depends on which enzyme they are

Enzymes

They are proteins



Substrates fit into the enzyme at the active site



Substrates will only fit into the active site that has a complimentary shape to each other



If the shape of the enzyme changes, its active site may no longer work

Enzymes

Extreme pH and High temperature may cause the enzyme to become denatured

Inspiration

External intercostal muscles contract


Internal intercostal muscles relax



Ribs move up and out


Diaphragm contracts and flattens



Volume in the thorax increases


Pressure in the thorax decreases, Air moves in

Expiration

External intercostal muscles relax


Internal intercostal muscles contract



Ribs move down and in


Diaphragm relaxes and becomes curved



Volume in the thorax decreases


Pressure in the thorax increases, Air moves out

Pulmonary Ventilation

Tidal Volume x Ventilation rate

Fick's Law

Cardiac Output

Stroke Volume x Heart rate

Heartbeat Control

Electrical impulses travel through this route




AVN->Collagen Tissue->SAN->Bundle His->Purkinje Fibres

Cardiac Cycle (Short form)

Atrial Systole - Ventricles Relaxed, Atria Contract



Ventricular Systole- Ventricles contract, Atria Relaxed



Diastole- Ventricles Relaxed, Atria Relaxed

Cardiovascular Disease:


Atheromas

Endothelium is usually smooth and unbroken



Damage occurs to the endothelium and white blood cells and lipids clump together to form fatty streaks



Over time , this builds up to for a fibrous plaque



This partially blocks the lumen and restricts blood flow and increases blood pressure

Cardiovascular Disease:


Aneurysm

Atheroma plaques weaken and damage arteries as well as increasing blood pressure



When blood travels through a weakened artery at high pressure it may push the inner layers of the artery though the outer elastic layer to form a balloon like swelling- an aneurysm



This aneurysm may burst causing a haemorrhage

Cardiovascular Disease:


Thrombosis

An atheroma plaque can rupture the endothelium of an artery



This damages the artery wall and leaves a rough surface



Platelets and fibrin accumulate at the site of damage and form a blood clot



This blood clot can cause a compete blockage of the artery or it can be blocked and dislodge another artery elsewhere

Antigens

Antigens are molecules which are identified as foreign and trigger an immune response

Phagocytosis

A phagocyte recognises the antigens on a pathogen



Phagocyte engulfs the pathogen



Pathogen is now contained in a phagocytic vacuole in the cyptoplasm



A lysome releases hydrolytic enzymes to break down the pathogen



The phagocyte then presents the pathogen's antigens- it sticks the antigen on its surface to activate other immune system cells


Pathogens

Pathogens Cause disease by either releasing toxins or damaging the host tissue

T Cells

T cells are cell mediated responses



If an antigen is present with a complimentary shaped receptor, the T Cell is stimulated increases is size and starts to divide


T Cells

When T Cells divide, they :



Kill infected cells


Stimulate phagocytes to engulf pathogens


Stimulate B cells to divide


Develop memory cells that enable a rapid response in the future

B Cells

When the antibody of a B Cell meets a complimentary shaped antigen, it binds to it



This, together with substances released from T Cells, activates B Cells



Th activated B Cell divides to form plasma cells

Plasma Cells

They make more Antibodies to a specfic Antigen

Immune Response can be Memorised

Primary Response- Slow, takes time to produce right antibodies needed to bind it , Memory Cells produced which record specific antibodies needed to bind to the antigen



Immune Response can be Memorised

Secondary Response- Same pathogen enters, quicker response, memory b cells divide into plasma cells and produce the right antibody to the antigen. Memory T Cells divide into the correct type of T Cells to kill the cell carrying the antigen