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40 Cards in this Set
- Front
- Back
Nucleus |
Contains genetic material which controls the activities of the cell |
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Cyptoplasm |
most chemical processes take place here, controlled by enzymes |
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Cell Membrane |
Controls movement of substances into and out of the cell |
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Mitochondria |
Most energy is released by respiration here
Site of Respiration, ATP production |
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Ribosomes |
Protein synthesis happens here |
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Golgi Apparatus |
Processes and packages new lipids and proteins. It also makes lysosomes |
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Rough Endolplasmic Reticulum |
Folds and processes proteins that have been made at the ribosomes |
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Smooth Endoplasmic Reticulum |
Synthesizes and processes lipids |
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Types of Diffusion |
Diffusion
Osmosis
Active Transport |
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Diffusion |
Movement of particles from a high concentration to a low concentration down a concentration gradient |
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Osmosis |
Net diffusion of particles from a solution with a high water potential to a solution with a low water potential down a concentration gradient |
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Active Transport |
Uses Energy to move molecules and ions against a concentration gradient |
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Facillitated Diffusion |
Some larger molecules (eg. Amino Acids, Glucose) and ions can't diffuse directly through the phospholipid bilayer of the cell membrane.
Insted they diffuse through carrier proteins or protein channels in the cell membrane |
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Carrier Proteins |
Move large molecules into or out of the cell.
1. Large molecule attatches itself to the carrier protein
2. Then the protein changes shape
3. This releases the molecules on to the opposite side of the membrane |
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Protein Channels |
Form pores in the membranes for charged particles to diffuse through
Different protein channels facillitate the diffusion of different charged particles |
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Properties of Fluid Plasma Membrane |
1. Membrane is a good barrier against most water soluble molecules
2. The membrane contorls what enters and leaves
3. The membrane allows cell communication
4. The membrane allows cell recognition
5. The membrane is fluid |
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Prokaryotic Cell |
Single celled organisms |
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Eukaroytic Cell |
Multi cellular organism with specialised organelle inside |
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Enzymes |
They are biological catalysts, they speed up the reaction without being used up
They work best at the optimum temperature of 37C
They have an optimum pH which depends on which enzyme they are |
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Enzymes |
They are proteins
Substrates fit into the enzyme at the active site
Substrates will only fit into the active site that has a complimentary shape to each other
If the shape of the enzyme changes, its active site may no longer work |
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Enzymes |
Extreme pH and High temperature may cause the enzyme to become denatured |
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Inspiration |
External intercostal muscles contract Internal intercostal muscles relax
Ribs move up and out Diaphragm contracts and flattens
Volume in the thorax increases Pressure in the thorax decreases, Air moves in |
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Expiration |
External intercostal muscles relax Internal intercostal muscles contract
Ribs move down and in Diaphragm relaxes and becomes curved
Volume in the thorax decreases Pressure in the thorax increases, Air moves out |
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Pulmonary Ventilation |
Tidal Volume x Ventilation rate |
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Fick's Law |
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Cardiac Output |
Stroke Volume x Heart rate |
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Heartbeat Control |
Electrical impulses travel through this route
AVN->Collagen Tissue->SAN->Bundle His->Purkinje Fibres |
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Cardiac Cycle (Short form) |
Atrial Systole - Ventricles Relaxed, Atria Contract
Ventricular Systole- Ventricles contract, Atria Relaxed
Diastole- Ventricles Relaxed, Atria Relaxed |
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Cardiovascular Disease: Atheromas |
Endothelium is usually smooth and unbroken
Damage occurs to the endothelium and white blood cells and lipids clump together to form fatty streaks
Over time , this builds up to for a fibrous plaque
This partially blocks the lumen and restricts blood flow and increases blood pressure |
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Cardiovascular Disease: Aneurysm |
Atheroma plaques weaken and damage arteries as well as increasing blood pressure
When blood travels through a weakened artery at high pressure it may push the inner layers of the artery though the outer elastic layer to form a balloon like swelling- an aneurysm
This aneurysm may burst causing a haemorrhage |
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Cardiovascular Disease: Thrombosis |
An atheroma plaque can rupture the endothelium of an artery
This damages the artery wall and leaves a rough surface
Platelets and fibrin accumulate at the site of damage and form a blood clot
This blood clot can cause a compete blockage of the artery or it can be blocked and dislodge another artery elsewhere |
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Antigens |
Antigens are molecules which are identified as foreign and trigger an immune response |
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Phagocytosis |
A phagocyte recognises the antigens on a pathogen
Phagocyte engulfs the pathogen
Pathogen is now contained in a phagocytic vacuole in the cyptoplasm
A lysome releases hydrolytic enzymes to break down the pathogen
The phagocyte then presents the pathogen's antigens- it sticks the antigen on its surface to activate other immune system cells
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Pathogens |
Pathogens Cause disease by either releasing toxins or damaging the host tissue |
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T Cells |
T cells are cell mediated responses
If an antigen is present with a complimentary shaped receptor, the T Cell is stimulated increases is size and starts to divide
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T Cells |
When T Cells divide, they :
Kill infected cells Stimulate phagocytes to engulf pathogens Stimulate B cells to divide Develop memory cells that enable a rapid response in the future |
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B Cells |
When the antibody of a B Cell meets a complimentary shaped antigen, it binds to it
This, together with substances released from T Cells, activates B Cells
Th activated B Cell divides to form plasma cells |
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Plasma Cells |
They make more Antibodies to a specfic Antigen |
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Immune Response can be Memorised |
Primary Response- Slow, takes time to produce right antibodies needed to bind it , Memory Cells produced which record specific antibodies needed to bind to the antigen
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Immune Response can be Memorised |
Secondary Response- Same pathogen enters, quicker response, memory b cells divide into plasma cells and produce the right antibody to the antigen. Memory T Cells divide into the correct type of T Cells to kill the cell carrying the antigen |