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26 Cards in this Set
- Front
- Back
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Ratio of iron to porphyrin in heme. |
1:1 |
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Hemoglobins present in normal adult. |
Hb-A1 Hb-A2 Hb-F |
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Hemoglobin C. |
Rod-shaped crystals |
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Hemoglobin C, glutamic acid is replaced by? |
Lysine |
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Hemoglobin insoluble under lowered oxygen tension. |
Hb-S |
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Kleihauer technic used to differentiate? |
Hb-A2 from Hb-F |
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Neutrophil inclusions resembling Dohle bodies. |
May- Hegglin |
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Large dark granules in granulocytes caused by anomaly of primary granules & lymphocytes by lysosomal granules. |
Chediak - Higashi |
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Failure to complete development of nuclear lobes. |
Pelger - Huet |
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Dense granulation of granulocytes and lymphocytes caused by abnormal enzyme. |
Alder - Reilly |
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Differentiate AML from ALL? |
Auer rods in blast cells |
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Immediate precursor of “band” PMN. |
Metamyelocyte |
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Largest leukocyte in the normal peripheral blood smear. |
Monocyte |
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Shift to the left, increase in. |
Immature granulocytes |
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Chronic lymphocytic leukemia |
Lymphocytosis |
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Chronic granulocytic leukemia. |
Leukopenia |
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An absolute increase in small “hypermature” lymphocytes and “smudge” cells. |
CLL |
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95% of chronic lymphocytic leukemias |
B cells |
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Most reliable criteria for estimating the cell’s age? |
Nuclear chromatin |
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Peripheral blood smear from a patient with thalassemia? |
Target cells, nRBCs & basophilic stippling |
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Thalassemia? |
Low serum iron, increased TIBC |
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Second most common abnormal hemoglobin in the WORLD, which predominates in southeast Asians? |
Hb-E |
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Autoantibody that has maximal intravascular hemolysis at low temp. |
IgM-binding complement |
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FAB classification of the lymphocytic leukemia with prominent cytoplasmic vacuolation? |
L3 |
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Acute lymphocytic leukemias that have a predominance of homogenous cells with a high N/C ratio belong to which FAB group? |
L1 |
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Myeloid metaplasia. |
Anemia, teardrop cells, low alkaline phosphatase, increased uric acid |
