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95 Cards in this Set
- Front
- Back
The nervous system has two major anatomical subdivisions:
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central nervous system (CNS)
peripheral nervous system (PNS) |
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consists of the brain and spinal cord
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central nervous system (CNS)
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consists of all the nervous system except the brain and spinal cord. It is composed of nerves and ganglia
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peripheral nervous system (PNS)
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fibers always conduct signals away from the CNS
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Motor (efferent)
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fibers always conduct signals toward the CNS
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Sensory (afferent)
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fibers innervate skeletal muscle, the skin, bones, and joints.
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Somatic
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fibers innervate cardiac muscle, smooth muscle, and glands.
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Visceral
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There are three general classes of neurons;
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Sensory (afferent) neurons, Interneurons (association neurons), and motor (efferent) neurons
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About 90% of our neurons are
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interneurons
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The control center of the neuron is the
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soma
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also called the neurosoma, cell body, or perikaryon
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soma
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There are six kinds of neuroglia (glial cells)
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Four types occur only in the CNS, and two occur only in the PNS.
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Oligodendrocytes produce the myelin in the CNS, and Schwann cells produce the myelin in the PNS
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two occur only in the PNS
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Since the myelin consists of the plasma membranes of these glial cells, its composition is like that of plasma membranes in general
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It is 80% lipid and 20% protein
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They resemble a cuboidal epithelium, line the internal cavities of the brain and spinal cord, and are responsible for the production of cerebrospinal fluid (CSF)
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Ependymal cells are found only in the CNS
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They are the most abundant glial cells in the CNS
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Astrocytes
are also found only in the CNS and are responsible for formation of the blood-brain barrier |
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are the macrophages of the CNS
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Microglia
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have one axon and multiple dendrites
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Multipolar neurons
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have one axon and one dendrite
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Bipolar neurons
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have only a single process leading away from the soma
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Unipolar neurons
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Conduction speed of nerve fibers depends on two factors:
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the diameter of the fiber and the presence or absence of myelin
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Large diameter fibers conduct signals
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more rapidly than small diameter fibers
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Myelinated fibers conduct signals
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more rapidly than unmyelinated fibers
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the fastest signal-conducting fibers in our nervous system are large
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myelinated fibers
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The myelin covering a nerve fiber is
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segmented
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The myelinated segments are called
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internodes
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the unmyelinated gaps in between the myelinated segments are called
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nodes of Ranvier
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In order for a peripheral nerve fiber to regenerate it must have an
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intact soma and at least some neurilemma intact
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Damaged nerve fibers in the CNS cannot
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regenerate
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Potassium ions have the greatest influence on the resting membrane potential (RMP)
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because the plasma membrane is more permeable to potassium than any other ion
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the opening of sodium gates causes sodium ions to come into the cell, which leads to depolarization of the plasma membrane
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During an action potential
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Chloride ions, being negatively charged, cause the membrane potential to become more negative when they enter the cell. When a cell is at its RMP, any decrease in voltage that causes the voltage to become more negative than the RMP is called
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hyperpolarization
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At threshold
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both sodium and potassium gates are opening
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___________ of an action potential no stimulus of any strength will trigger a new action potential
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During the absolute refractory period
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____________ it is possible to trigger a new action potential, but only with an unusually strong stimulus
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During the relative refractory period
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____________ each action potential at the current node has the same strength as the one at the previous node
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saltatory conduction
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Synapses that employ acetylcholine as the neurotransmitter are called
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cholinergic synapses
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Amino acid neurotransmitters include,
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glycine, glutamate, aspartate, and gamma-aminobutyric acid (GABA)
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There are four major classes of neurotransmitters
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Acetylcholine is in a class by itself
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GABA is considered an inhibitory neurotransmitter
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because the binding of GABA to its receptor opens chloride(Cl-) gates that hyperpolarize the membrane
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The monoamines include
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norepinephrine, epinephrine, dopamine, and others
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The monoamines act through second-messenger systems such as
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cyclic AMP.
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The neuropeptides are
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chains of 2 to 40 amino acids. Some examples are beta-endorphin and substance P
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Even though all action potentials are the same, the brain can differentiate a variety of stimuli by source and intensity. The mechanism by which the nervous system converts these action potentials into meaningful information is called
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neural coding
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Synapses are not fixed for life; in response to experience, they can be added, taken away, or modified to make transmission easier or harder. This ability of synapses to change is called
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synaptic plasticity
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________ is the ability to hold something in mind for just a few seconds
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Immediate memory
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________ lasts from a few seconds to a few hours
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Short-term memory
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lasts up to a lifetime
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Long-term memory
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The meninges of the spinal cord from superficial to deep
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dura mater (dural sheath), arachnoid mater, and pia mater
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The spinal cord is divided into
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cervical, thoracic, lumbar, and sacral regions
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The space between the dura mater and vertebral bones is called the
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epidural space
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_______ is introduced into this space to block pain signals during pregnancy
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Epidural anesthesia
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The space between the arachnoid mater and pia mater is the
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subarachnoid space
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The subarachnoid space is filled with
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cerebrospinal fluid (CSF)
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The spinal cord has a central core of gray matter surrounded by
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white matter.
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The gray matter contains
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the somas, dendrites, and proximal parts of axons of neurons
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The white matter contains bundles of myelinated fibers called
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tracts running up and down the spinal cord
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Ascending tracts carry sensory signals
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up the spinal cord
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Descending tracts carry motor signals down
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the brainstem and spinal cord
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When the origin and destination of a tract are on opposite sides of the body we say they are
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contralateral to each other
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In most nerves, the nerve fibers are gathered in bundles called
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fascicles, with each fascicle wrapped in a sheath called the perineurium
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The connective tissue sheath surrounding the entire nerve is the
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epineurium
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The ventral (anterior) rami of the spinal nerves form five weblike nerve plexuses:
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cervical, brachial, lumbar, sacral, and coccygeal
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The most important nerve of the cervical plexus is the
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phrenic nerve, which plays an essential role in breathing
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The tibial and common fibular nerves travel together through a
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connective tissue sheath, and are collectively referred to as the sciatic nerve
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The gray matter contains
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the somas, dendrites, and proximal parts of axons of neurons
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The white matter contains bundles of myelinated fibers called
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tracts running up and down the spinal cord
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Ascending tracts carry sensory signals
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up the spinal cord
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Descending tracts carry motor signals down
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the brainstem and spinal cord
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When the origin and destination of a tract are on opposite sides of the body we say they are
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contralateral to each other
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In most nerves, the nerve fibers are gathered in bundles called
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fascicles, with each fascicle wrapped in a sheath called the perineurium
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The connective tissue sheath surrounding the entire nerve is the
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epineurium
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The ventral (anterior) rami of the spinal nerves form five weblike nerve plexuses:
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cervical, brachial, lumbar, sacral, and coccygeal
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The most important nerve of the cervical plexus is the
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phrenic nerve, which plays an essential role in breathing
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The tibial and common fibular nerves travel together through a
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connective tissue sheath, and are collectively referred to as the sciatic nerve
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The gray matter contains
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the somas, dendrites, and proximal parts of axons of neurons
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The white matter contains bundles of myelinated fibers called
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tracts running up and down the spinal cord
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Ascending tracts carry sensory signals
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up the spinal cord
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Descending tracts carry motor signals down
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the brainstem and spinal cord
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When the origin and destination of a tract are on opposite sides of the body we say they are
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contralateral to each other
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In most nerves, the nerve fibers are gathered in bundles called
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fascicles, with each fascicle wrapped in a sheath called the perineurium
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The connective tissue sheath surrounding the entire nerve is the
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epineurium
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The ventral (anterior) rami of the spinal nerves form five weblike nerve plexuses:
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cervical, brachial, lumbar, sacral, and coccygeal
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The most important nerve of the cervical plexus is the
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phrenic nerve, which plays an essential role in breathing
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The tibial and common fibular nerves travel together through a
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connective tissue sheath, and are collectively referred to as the sciatic nerve
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is a diagram of the cutaneous regions innervated by each spinal nerve. Because dermatomes overlap at their edges by as much as 50%, it is necessary to sever or anesthetize three successive spinal nerves to produce a total loss of sensation from one dermatome.
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A dermatome map
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Four important properties of a reflex:
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1. Reflexes require stimulation and do not occur spontaneously; they are responses to sensory input.
2. Reflexes are very predictable. They occur in essentially the same way every time. 3. Reflexes are involuntary. 4. Reflexes are quick and generally involve few if any interneurons. |
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__________ has three principal classes of nerve fibers. A primary (group Ia) fiber, a secondary (group II) fiber, and a gamma motor neuron.
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A muscle spindle
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Muscle spindles are
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proprioceptors that respond to stretch
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Proprioceptors are sense organs which are
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specialized to monitor the position and movement of body parts
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A somatic reflex employs a reflex arc, in which signals travel along the following pathway:
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somatic receptor >>> afferent nerve fiber >>> integrating center >>> efferent nerve fiber >>> skeletal muscle
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The quickest reflex arcs involve only two neurons, thus forming
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monosynaptic reflex arcs
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The muscle fibers within a muscle spindle are called intrafusal fibers,
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while those that make up the rest of the muscle and do its work are called extrafusal fibers.
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When a muscle is stretched, it “fights back”. It contracts and feels stiffer than an unstretched muscle. This response is called the
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stretch (myotatic) reflex
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The tendon reflex is a response to excessive tension on the tendon.
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It inhibits alpha motor neurons to the muscle so the muscle does not contract as strongly.
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