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28 Cards in this Set

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Describe several ways in which hormone secretion is regulated.
Hormone secretion is regulated by signals from the nervous system, chemical changes in the blood, and other hormones
Most hormonal regulatory systems work via negative feedback, but a few operate via positive feedback
Choose your favorite feedback mechanism and discuss it in detail.
Blood Ca2+ level is controlled by the parathyroid hormone (PTH). If blood Ca2+ is low, there is a stimulus for the parathyroid glands to release more PTH. PTH then exerts its effects in the body until the Ca2+ level returns to normal. If the level gets too high the body will cease PTH production and secrete calcitonin lower the Ca2+ levels.
What would happen if a person with type A blood were to receive a transfusion of type B blood?
In a blood transfusion, if the recipient receives the wrong blood type, antigen-antibody reactions will cause a rapid destruction (hemolysis) of the donor red blood cells
Describe the mechanism of action for a lipid-soluble hormone, and provide an example.
1. Lipid-soluble hormone diffuses into cell
2. Activated receptor-hormone complex alters gene expression
3. Newly formed mRNA directs synthesis of
specific proteins on ribosomes
Example is Steroids or Thyroid hormones
List the correct order the action of a water soluble hormone on its target cell.
1. The hormone binds to a membrane receptor
2. The hormone receptor complex activates G proteins.
3. Adenylate cyclase is activated, catalyzing the conversion of ATP to cAMP.
4. Cyclic AMP activates protein kinases
5. Activated protein kinases phosphorylate cellular proteins.
6. Enzymes Catalyze reactions that produce a physiological response attributed to the hormone.
Example is Amine, peptide, protein, and eicosanoid hormones.
List several ways in which lipid-soluble and water-soluble hormones “behave” differently.
Lipid soluble hormones bind to receptors in the cytoplasm or nucleus of the cell
Water soluble hormones bind to receptors on the surface of the cell
Water soluble hormones cirulate in the blood plasma membrane in a free form not attched to plasma proteins; most lipid soluble hormones are bound to transport proteins synthesized by the liver.
Give an example of a medical condition resulting from a hormone imbalance/deficiency.
Hypersecretion of Cortisol by the adrenal cortex produces crushing syndrome. A condition in which the body breaksdown muscle and redistributes body fat.
Select an endocrine gland. Describe the hormone(s) that are secreted by this gland and the action that they bring about.
Adrenal Cortex secretes Cortisol. Cortisol binds to smooth muscle in blood vessels. Cause blood vessels to constrict maintaining blood flow during stress. Increases the bodys ability to cope with stress.
What are the three main functions of blood? Describe each briefly.
1. Transportation: Blood contributes to homeostasis by transporting respiratory gasses, nutrients, and hormones to and from your body’s cells.
2. Regulation: It helps regulate body pH and temperature
3. Protection: It provides protection through its clotting mechanisms and immune defenses.
How is oxygen carried by blood?
Oxygen is carried by red blood cells. Red blood cells contain hemoglobin which is a oxygen carrying protein.
You are a nurse at South Georgia Medical, a patient presents to you and your doctor with symptoms that suggest an infection. Your doctor orders a blood test. Why? Be specific.
The doctor orders the test to check for high or low leves of white blood cell counts.High levels of Neutrophils, Lymphocytes or Monocytes may suggest a Infection.
Describe a specific type of anemia
Anemia is a condition of insufficient RBC’s or hemoglobin (quality or quantity). Iron deficiency anemia is the most common anemia in the U.S., and affects primarily menstruating women
How does medicine such as Tylenol know where in the body to go?
Because of specific receptors
What are three stages to a general adaptation syndrome response?
1 alarm reaction (Fight or Flight)
2 Resistance reaction
3.Exhaustion
Describe the Alarm reaction of the GAS.
The alarm reaction is the short-lived fight-or-flight response initiated by the hypothalamus and mediated by the sympathetic division of the ANS
it brings huge amounts of glucose and oxygen to the brain, the lungs, and skeletal muscles
the RAAS is also activated to maintain blood volume and BP
Describe the resistance reaction of the GAS.
The resistance reaction is initiated in large part by hypothalamic releasing hormones and is a longer-lasting response. The release of high levels of cortisol and thyroid hormones assures that the tissues of the body can sustain necessary metabolic needs
Describe the Exhaustion reaction of the GAS.
Exhaustion occurs when the body’s reserves become so depleted that they cannot sustain the resistance stage
Glands that secrete endocrine hormones into the bloodstream are called?
endocrine glands
Glands that secrete their products into ducts are called?
exocrine glands
What are hormones produced and secreted by the anterior pituitary that target other endocrine glands?
Tropic hormones
What are local hormones that are secreted into interstitial fluid and act on nearby cells?
Paracrine hormones
Some hormones, called _____ ____ are local hormones that are secreted, and bind to the same cell.
autocrine hormones
What are the normal levels of the white blood cells called Neutrophils?
60-70%
What are the normal levels of the white blood cells called Eosinophils?
2-4%
What are the normal levels of the white blood cells called Basophils?
.5-1%
What are the normal levels of the white blood cells called Lymphocytes?
20-25%
What are the normal levels of the white blood cells called Monocytes?
3-8%
List the white blood cells from the largest percentage to the smallest. (N L M E B). Nice long mercades equal bucks.
Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils.