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72 Cards in this Set

  • Front
  • Back

In liver cells, the inner mitochondrial membranes are about five times the area of the outer mitochondrial membranes. What purpose must this serve?

It increases the surface for oxidative phosphorylation.

Which statement best supports the hypothesis that glycolysis is an ancient metabolic pathway that originated before the last universal common ancestor of life on Earth?

Glycolysis is widespread and is found in the domains Bacteria, Archaea, and Eukarya.

Why are carbohydrates and fats considered high energy foods?

They have a lot of electrons associated with hydrogen

Which catabolic processes may have been used by cells on ancient Earth before free oxygen became available?

Glycolysis, pyruvate oxidation, the citric acid cycle, and oxidative phosphorylation, using an electron acceptor other than oxygen

An electron loses potential energy when it

Shifts to a more electronegative atom

During cellular respiration, acetyl CoA accumulates in which location?

mitochondrial matrix

The transport of pyruvate into the mitochondria depends on the proton-motive force across the inner mitochondrial membrane. How does pyruvate enter the mitochondrion?

active transport

In prokaryotes, the respitory electron transport chain is located

In the plasma membrane

Which kind of metabolic poison would most directly interfere with glycolysis?

An agent that closely mimics the structure of glucose but is not metabolized

Energy released by the electron transport chain is used to pump H+ into which location in eukaryotic cells?

mitochondrial intermebrane space

Why is glycolysis described as having an investment phase and a payoff phase?

It uses stored ATP and then forms a net increase in ATP

Which process in eukaryotic cells will proceed normally whether oxygen (O2) is present or absent?

glycolysis

Which of the following most accurately describes what is happening along the electron transport chain in figure 9.3?

Each electron carrier alternates between being reduced and being oxidized.

The ATP made during glycolysis is generated by

substrate-level phosphorylation

In a mitochondrion, if the matrix ATP concentration is high and the intermembrane space proton concentration is too low to generate sufficient proton-motive force, then

ATP synthase will hydrolyze ATP and pump protons into the intermembrane space

If a cell is able to synthesize 30 ATP molecules for each molecule of glucose completely oxidized by carbon dioxide and water, how many ATP molecules can the cell synthesize for each molecule of pyruvate oxidized to carbon dioxide and water?

12

When a glucose molecule loses a hydrogen atom as the result of an oxidation-reduction reaction, the molecule becomes

oxidized

Which of the following produces the most ATP when glucose is completely oxidized to carbon dioxide and water?

Oxidative phosphorylation (chemiosmosis)

Chemiosmotic ATP synthesis (oxidative phosphorylation) occurs in

All respiring cells, both prokaryotic and eukaryotic, using either oxygen or other electron acceptors.

It is possible to prepare vesicles from portions of the inner mitochondrial membrane. Which one of the following processes could still be carried on by this isolated inner membrane?

oxidative phosphorylation

Which of the following intermediary metabolites enters the citric acid cycle and is formed, in part by the removal of a carbon from one molecule of pyruvate?

Acetyl CoA

When skeletal muscles cells are oxygen-deprived, the heart still pumps. What must the heart muscle cells be able to do?

Continue aerobic metabolism when skeletal muscles cannot

Why is glycolysis considered to be one of the first metabolic pathways to have evolved?

It does not involve organelles or specialized structures, does not require oxygen, and is present in most organisms

The molecule that functions as the reducing agent (electron donor) in a redox or oxidation-reduction reaction

loses electrons and loses potential energy

When electrons move closer to a more electronegative atom, what happens?

The more elctronegative atom is reduced, and energy is released

What is proton-motive force?

The force exerted on a proton by a transmembrane proton concentration gradient

What fraction of the carbon dioxide exhaled by animals is generated by the reactions of the citric acid cycle, if glucose is the sole energy source?

2/3

Which of the following normally occurs regardless of whether or not oxygen is present?

glycolysis

Where are the proteins of the electron transport chain located?

mitochondrial inner membrane

In chemiosmotic phosphorylation, what is the most direct source of energy that is used to convert ADP + Pi to ATP?

Energy released from movement of protons through ATP synthase, down the electrochemical gradient

Which metabolic pathway is common to both cellular respiration and fermentation?

glycolysis

The synthesis of ATP by oxidative phosphorylation, using the energy released by movement of protons across the membrane down their electochemical gradient is an example of

an endergonic reaction coupled to an exergonic reaction

Inisde an active mitchondrion most electrons follow which pathway?

citric acid cycle --> NADH --> electron transport chain --> oxygen

A young animal never has much energy. He is brough to a veterinarian for help and is sent to an animal hospital for some tests. There they discover his mitochondria can use only fatty acids and amino acids for respiration, and his cells produce more lactate than normal. Of the following, which is the best explanatiion of his condition?

His mitchondria lack the transport protein that moves pyruvate across the outer mitchondrial membrane

The oxygen consumed during cellular respiration is involved directly in which process or event?

Accepting electrons at the end of the electron transport chain

During intense exercise, as the skeletal muscle cells go into anaerobiosis, the human body will increase its catabolism of

carbohydrates only

Why does the oxidation of organic compounds by molecular oxygen to produce CO2 and water release free energy?

Electrons are being moved from atoms that have a lower affinity for electrons (such as C) to atoms with a higher affinity for electrons (such as O)

Substrate-level phosphorylation accounts for approximately what precentage of the ATP formed by the reactions of glycolysis?

100%

In alcohol fermentation, NAD+ is regenerated from NADH by

reduction of ecetaldehyde to ethanol (ethyl alcohol)

An organism is discovered that thrives in bothe the presence and absence of oxygen in the air. Curiously, the consumption of sugar increases as oxygen is removed from the organism's environment, even though the organism does not gain much weight. This organism

is a faculative anaerobe

You have a friend who lost 7 kg (about 15 pounds) of fat on a regimen of strict diet and exercise. How did the fat leave her body?

It was released as CO2 and H2O

During aerobic respiration which of the following directly donates electrons to the electron transport chain at the lowest energy level?

FADH2

Where is ATP synthase located in the mitochondrion?

inner membrane

In addition to ATP, what are the end products of glycolysis?

NADH and pyruvate

The direct energy source that drives ATP synthesis during respiratory oxidative phosphorylation in eukaryotic cells is

the proton-motive force across the inner mitochondrial membrane

Which of the following statements describes NAD+

NAD+ is reduced to NADH during glycolysis, pyruvate oxiidation, and the citiric acid cycle

When the individual is exercising heavily and when the muscle becomes oxygen-deprived, muscle cells convert pyruvate to lactate. What happens to the lactate in skeletal muscle cells?

It is taken to the liver and converted back to pyruvate

During aerobic repiration, electron travel downhill in which sequence?

food --> citric acid cycle --> ATP --> NAD+

Where does glycolysis take place in eukaryotic cells?

cytosol

What is the term for metabolic pathways that release stored energy by breaking down complex molecules?

catabolic pathways

When skeletal muscle cells undergo anaerobic respiration, they become fatigued and painful. This is now known to be caused by

buildup of lactate

In cellular respiration the energy for most ATP synthesis is supplied by

A proton gradient across a membrane

Brown fat cells produce a protein called thermogenin in their mitochondrial inner membrane. Thermogenin is a chennel for facilitated transport of protons across the membrane. What will occur in the brown fat cells when they produce thermogenin?

ATP synthesis will decrease, and heat generation will increase

During aerobic respiration H20 is formed. Where does the oxygen atom for the formation of the water come from?

molecular oxygen (02)

Starting with one molecule of glucose, the energy-containing products of glycolysis are

2 NADH, 2 pyruvate, and 2 ATP

How many carbon atoms are fed into the citric acid cycle as a result of the oxidation of one molecule of pyruvate?

two

The primary role of oxygen in cellular respiration is to

act as an acceptor for electrons and hydrogen froming water

A molecule that is phosphorylated

has an increased chemical potential energy; it is primed to do cellular work

When hydrogen ions are pumped from the mitochondrial matrix across the inner membrane and into the intermembrane space, the result is the

creation of proton-motive force

A mutationn in yeast makes it unable to convert pyruvate to ethanol. How will this mutation affect these yeast cells?

The mutant yeast will be unable to grow anaerobically

In the absence of oxygen, yeast cells can obtain energy by fermentation, resulting in the production of

ATP, CO2, and ethanol (ethyl alcohol)

One function of bothe alcohol fermentation and latic acid fermentation is to

reduce FADH2 to FAD+

The ATP made during fermentation is generated by which of the following?

substrate-level phosphorylation

Which of the following statements describes the results of this reaction C6H1206 + 6CO2 --> 6CO2 + 6H20 + ENERGY ?

C6H1206 is oxidized and O2 is reduced

In glycolysis for each molecule of glucose oxidized to pyruvate

two molecules of ATP are used and four molecules of ATP are produced

How many oxygen molecules are required each time a molecule of glucose (C6H12O6) is completely oxidized to carbon dioxide and water via aerobic respiration?

6

Which of the following occurs in the cytosol of a eukaryotic cell?

glycolysis and fermentation

The free energy for the oxidation of glucose to CO2 and water is -686 kcal/mol and the free energy for the reuction of NAD+ to NADH is +53 kcal/mol. Why are only two molecules of NADH formed during glycolysis when it appears that as many as a dozen could be formed?

Most of the free energy available from the oxidation of glucose remains in pyruvate, one of the products of glycolysis

Carbon dioxide is released during which of the following stages of cellular respiration?

Oxidative of pyruvate to acetyl CoA and the citric acid cycle

During glycolysis, when each molecule of glucose is catabolized to two molecules of pyruvate most of the potential energy contained in glucose is

retained in two pyruvates

When a molecule of NAD+ (nicotinamide adenine dinucleotide) gains a hydrogen atom (not a proton), the molecule becomes

reduced

Approximately how many molecules of ATP are produced from the complete oxidation of two molecules of glucose in aerobic cellular respiration?

60-64