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120 Cards in this Set
- Front
- Back
What is the main function of the liver?
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To filter and process the nutrient-rich blood coming from the digestive organs
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What vein delivers the nutrient-rich blood to the liver?
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The hepatic portal vein
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What are the hexagonal structures in the liver called? What are the rows radiating out of the central vein called?
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Lobules, hepatocytes
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What three vessels are found in the portal triad?
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Portal Arterioles, portal venule, and bile ducts
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These guys connect the portal triad vessels with the central vein:
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Sinusoids
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What cells are found in the sinusoids that remove bacteria and cellular debris?
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Macrophages
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Where does the central vein drain into? Where do these vessels then drain into?
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Hepatic veins; inferior vena cava
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Where does the small bile duct in the triad empty into?
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The common hepatic duct
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What is the purpose of the hepatocytes?
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Process nutrients, store vitamins, and remove toxins
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Bile flows through the __________ to the bile ducts in the portal triads
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Canaliculi
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Inflammation of the liver
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Hepatitis
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What is cirrhosis?
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Infiltration of the of the liver with scar tissue, due to long-term inflammation (viral infection, alcohol)
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What problems does the scar tissue cause in the liver?
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Obstructs blood flow, causes portal hypertension. This causes elevated pressure in the portal venous system
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What do bile salts do?
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Emulsify fats
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Bile salts are recycled through the:
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Enterohepatic circulation
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This is what's absorbed from the blood and excreted in the bile.
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Bilirubin
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What causes jaundice?
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Blockage of the bile duct, elevated bilirubin levels in blood, causes yellow coloration
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How much bile does the liver produce per day?
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500- 1000 ml per day
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How big is the gallbladder? (length)
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10 cm
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What is the gallbladders job?
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To store and concentrate bile |
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The gallbladder is attached to the bile duct by what?
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Attached to the bile duct by the cystic duct
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When does bile back up into the gallbladder?
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When the hepatopancreatic sphincter is closed, when NOT digesting
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What does chyme in the duodenum cause the release of?
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Cholecystokinin (CCK) - intestinal hormone
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What does CCK cause?
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Contraction of the Gallbladder and relaxation of the hepatopancreatic sphincter
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What causes gallstones?
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Bile contains cholesterol, forms gall stones, stone block cystic duct and produce pain, pass into bile duct
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The pancreas is located ________ to the stomach and is retro____________.
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Posterior, retro peritoneal
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The ______ of the pancreas is encircled by the duodenum, the _____ is the mid-portion, and the ______ extends to the splenic hilum.
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Head, body, tail
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What does the pancreas do?
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Produces enzymes to break down all categories of food molecules (proteases, lipases, amylases, nucleases)
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Pancreatic juice exits through the ______ _______ ________, and ____________ into the duodenum
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Main pancreatic duct, ampulla
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Which duct enters the the duodenum proximal to the major papilla?
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The small accessory pancreatic duct
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These are clusters of cells that secrete enzyme-rich fluid:
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acini
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The pancreas secretes how much fluid daily?
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1200-1500ml
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The pancreatic duct cells secrete what type of fluid?
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bicarbonate-rich
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What does bicarbonate-rich fluid do for the duodenum?
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neutralizes the stomach acid
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These are the inactive molecules secreted by the pancreas: What happens to these molecules once they reach the duodenum and what do they do?
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proteases
they are activated by enzymes; and they prevent self-digestion |
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Are there active molecules secreted by the pancreas? What is the inactive one?
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yes; proteases
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What does chyme in the duodenum cause the release of?
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secretin and CCK
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What two functions does secretin have?
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stimulates pancreatic secretion and stimulates the production of bile by the liver
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What function does CCK have?
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stimulates pancreatic secretion
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How much HCO3 is produced in comparison to the amount of HCl made in the stomach?
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they are matched
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What does the HCl:HCO3 ratio do to the body during digestion?
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it prevents any significant pH changes in the blood during digestion
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How long does it take food to pass through the small intestine?
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3-6 hours
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What is absorbed in the small intestine?
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nutrients and water
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What is another name for the cessation (the ending) of intestinal motility? and what is it usually caused by?
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paralytic ileus
injury to the small intestine |
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The large intestine starts at the ___________ _____ and ends at the _________
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ileocecal valve; anus
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Is the ileocecal valve considered a one-way valve?
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yes
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How long is the large intestine?
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4-5 feet
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Name the major functions of the large intestine:
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1. to absorb remaining water
2. site for temporary storage 3. eliminates feces |
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Is the longitudinal layer complete?
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no
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What are the three longitudinal bands of the small intestine called?
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tenaie coli
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These are the large sac-like projections of the wall of the large intestine
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haustra
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Name the divisions of the large intestine:
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cecum, appendix, colon, rectum, and anal canal
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What quadrant is the cecum located in?
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the right lower quadrant
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What is the appendix?
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a blind tube that extends from the base of the cecum
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What is the term for the inflammation of the appendix?
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appendicitis
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What causes appendicitis?
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blockage of the lumen
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what happens if appendicitis is allowed to persist?
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the appendix can rupture, leading to peritonitis (inflammation of the peritoneum that lines the abdominal organs)
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Name the divisions of the colon:
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ascending, hepatic flexure, transverse, splenic flexure, descending, and sigmoid colon
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Which areas of the colon are intra-peritoneal?
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transverse and sigmoid
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The transverse and sigmoid colons also contain:
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mesocolons or folds of peritoneum, or mesentery, attached to the colon
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Which divisions of the colon are considered retroperitoneal?
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ascending, hepatic flexure, splenic flexure, and descending colon
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The rectum lies just anterior to what two structures?
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the sacrum and the coccyx
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How long is the anal canal?
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3 cm long
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What is the external opening of the large intestine called?
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anus
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What is another name for the thickening of the inner circular layer of muscularis?
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the internal anal sphincter
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What type of muscle is the internal anal sphincter made up of? Is this muscle voluntary or involuntary?
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smooth; involuntary
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What type of muscle is the external anal sphincter made up of? Is this muscle voluntary or involuntary?
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skeletal muscle; voluntary
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What type of cells can be seen in the columnar mucosa of the large intestine?
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goblet cells
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True of false? The large intestine has thousands of villi along the wall that helps move food through the digestive tract.
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false
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The anal canal is lined with what type of tissue?
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stratified squamous epithelium
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What do the anal sinuses secrete?
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mucous
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This is the name of the line that runs just below the anal sinuses:
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pectinate or dentate line
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What type of sensory innervation is seen below the pectinate line? above?
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somatic (voluntary); visceral
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What part of the anal canal can cause hemorrhoids?
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the superficial venous plexuses
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Is the outer longitudinal muscle complete?
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yes the outer muscularis is complete
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Approximately how many species of bacteria exist in the colon? What are these referred to as?
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>700; bacterial flora
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Are the bacteria in the colon harmful?
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if they remain in the lumen, no
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Which vitamins do the bacteria in the colon produce? What do they help with?
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Vitamin B and vitamin K; used by the liver to synthesize clotting factors
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How long does it take food to pass through the large intestine?
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12-24 hours
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Is there any chemical digestion in the colon? What's absorbed here?
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no; vitamins and water
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True or false: The colon is essential to life.
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False
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Name the contractile waves in the large intestine. How are they activated?
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mass movements; by food entering the stomach
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How often do mass movements occur?
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3-4 times/day
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When mass movements are stimulated by food entering the stomach, we refer to this as the:
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gastrocolic reflex
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These are the small pouches of mucosa which protrude through the muscularis of the colon wall:
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diverticuli
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A person who has diverticuli has ___________ (condition). This is caused by what?
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diverticulosis
constipation |
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What is the name for an infected diverticulum?
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diverticulitis
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What do feces consist of?
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undigested food residue, mucous, sloughed epithelial cells, bacteria, and water
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When mass movements move feces into the rectum, dilation stimulates the :
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defecation reflex
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What parts of the colon contract during the defecation reflex? What relaxes?
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The sigmoid colon and the rectum contract, the internal anal sphincter relaxes
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Anything that increases the speed of passage through the large intestine will cause:
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diarrhea
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Inflammation of the mucosa in the large intestine will ultimately cause a person to have:
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diarrhea (from decreased water absorption)
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Anything that slows the passage of food through the large intestine will cause:
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constipation
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What usually causes constipation?
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a lack of fiber in the diet
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What other factors may cause constipation besides lack of fiber?
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medications, stress, and a lack of exercise
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What is the name for the inflammation of the GI mucosa?
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gastroenteritis
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What is the name for the inflammation of the gallbladder?
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cholecystitis
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Is it common to see the early stages of GI cancer? why or why not?
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no; the diameter of the tract is large
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Where do most metastases travel to once cancer has metastasized in the large intestine?
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to the liver
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Colon cancers originate from:
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benign polyps
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How are benign polyps removed?
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by colonoscopy
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Where does the celiac trunk branch from?
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the aorta
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What three branches does the celiac trunk divide into?
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the common hepatic, the splenic, and the left gastric arteries
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What does the common hepatic artery divide into?
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the gastroduodenal artery and the proper hepatic artery
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What organ(s) does the gastroduodenal artery supply?
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the stomach, the duodenum and the pancreas
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What organ(s) does the proper hepatic artery supply?
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the liver
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The splenic artery supplies which organs?
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the spleen, pancreas, and stomach
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The left gastric artery supplies blood to what organs?
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the proximal stomach and distal esophagus
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The superior mesenteric artery branches from the _________ and passes just inferior to the ________
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aorta, pancreas
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Where does the superior mesenteric artery enter?
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the mesentery of the small intestine
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What sections of the digestive tract does the superior mesenteric artery supply?
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the duodenum, jejunum, ileum, and first half of the small intestine
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What artery branch supplies the appendix and cecum?
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the ileocolic branch
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What section does the right colic branch supply? the middle colic?
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ascending colon; the transverse colon
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What supplies the distal half of the large intestine?
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the inferior mesenteric artery
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The left colic supplies what sections? the sigmoidal branch?
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the descending colon; the sigmoid
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What supplies the rectum with blood?
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the superior rectal branch
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All of the veins coming from the digestive organs come together to form the:
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hepatic portal vein
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The hepatic portal vein delivers blood to what organ? And what system is this a part of?
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the liver
the hepatic portal venous system |
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After leaving the liver, the blood then passes through the ______ _____ which drain into the ________ ________ _______
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hepatic veins
IVC (inferior vena cava) |
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Veins are named according to the corresponding ______ that supplies the organ
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artery
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