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120 Cards in this Set

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  • Back
What is the main function of the liver?
To filter and process the nutrient-rich blood coming from the digestive organs
What vein delivers the nutrient-rich blood to the liver?
The hepatic portal vein
What are the hexagonal structures in the liver called? What are the rows radiating out of the central vein called?
Lobules, hepatocytes
What three vessels are found in the portal triad?
Portal Arterioles, portal venule, and bile ducts
These guys connect the portal triad vessels with the central vein:
Sinusoids
What cells are found in the sinusoids that remove bacteria and cellular debris?
Macrophages
Where does the central vein drain into? Where do these vessels then drain into?
Hepatic veins; inferior vena cava
Where does the small bile duct in the triad empty into?
The common hepatic duct
What is the purpose of the hepatocytes?
Process nutrients, store vitamins, and remove toxins
Bile flows through the __________ to the bile ducts in the portal triads
Canaliculi
Inflammation of the liver
Hepatitis
What is cirrhosis?
Infiltration of the of the liver with scar tissue, due to long-term inflammation (viral infection, alcohol)
What problems does the scar tissue cause in the liver?
Obstructs blood flow, causes portal hypertension. This causes elevated pressure in the portal venous system
What do bile salts do?
Emulsify fats
Bile salts are recycled through the:
Enterohepatic circulation
This is what's absorbed from the blood and excreted in the bile.
Bilirubin
What causes jaundice?
Blockage of the bile duct, elevated bilirubin levels in blood, causes yellow coloration
How much bile does the liver produce per day?
500- 1000 ml per day
How big is the gallbladder? (length)
10 cm
What is the gallbladders job?

To store and concentrate bile
The gallbladder is attached to the bile duct by what?
Attached to the bile duct by the cystic duct
When does bile back up into the gallbladder?
When the hepatopancreatic sphincter is closed, when NOT digesting
What does chyme in the duodenum cause the release of?
Cholecystokinin (CCK) - intestinal hormone
What does CCK cause?
Contraction of the Gallbladder and relaxation of the hepatopancreatic sphincter
What causes gallstones?
Bile contains cholesterol, forms gall stones, stone block cystic duct and produce pain, pass into bile duct
The pancreas is located ________ to the stomach and is retro____________.
Posterior, retro peritoneal
The ______ of the pancreas is encircled by the duodenum, the _____ is the mid-portion, and the ______ extends to the splenic hilum.
Head, body, tail
What does the pancreas do?
Produces enzymes to break down all categories of food molecules (proteases, lipases, amylases, nucleases)
Pancreatic juice exits through the ______ _______ ________, and ____________ into the duodenum
Main pancreatic duct, ampulla
Which duct enters the the duodenum proximal to the major papilla?
The small accessory pancreatic duct
These are clusters of cells that secrete enzyme-rich fluid:
acini
The pancreas secretes how much fluid daily?
1200-1500ml
The pancreatic duct cells secrete what type of fluid?
bicarbonate-rich
What does bicarbonate-rich fluid do for the duodenum?
neutralizes the stomach acid
These are the inactive molecules secreted by the pancreas: What happens to these molecules once they reach the duodenum and what do they do?
proteases

they are activated by enzymes; and they prevent self-digestion
Are there active molecules secreted by the pancreas? What is the inactive one?
yes; proteases
What does chyme in the duodenum cause the release of?
secretin and CCK
What two functions does secretin have?
stimulates pancreatic secretion and stimulates the production of bile by the liver
What function does CCK have?
stimulates pancreatic secretion
How much HCO3 is produced in comparison to the amount of HCl made in the stomach?
they are matched
What does the HCl:HCO3 ratio do to the body during digestion?
it prevents any significant pH changes in the blood during digestion
How long does it take food to pass through the small intestine?
3-6 hours
What is absorbed in the small intestine?
nutrients and water
What is another name for the cessation (the ending) of intestinal motility? and what is it usually caused by?
paralytic ileus

injury to the small intestine
The large intestine starts at the ___________ _____ and ends at the _________
ileocecal valve; anus
Is the ileocecal valve considered a one-way valve?
yes
How long is the large intestine?
4-5 feet
Name the major functions of the large intestine:
1. to absorb remaining water
2. site for temporary storage
3. eliminates feces
Is the longitudinal layer complete?
no
What are the three longitudinal bands of the small intestine called?
tenaie coli
These are the large sac-like projections of the wall of the large intestine
haustra
Name the divisions of the large intestine:
cecum, appendix, colon, rectum, and anal canal
What quadrant is the cecum located in?
the right lower quadrant
What is the appendix?
a blind tube that extends from the base of the cecum
What is the term for the inflammation of the appendix?
appendicitis
What causes appendicitis?
blockage of the lumen
what happens if appendicitis is allowed to persist?
the appendix can rupture, leading to peritonitis (inflammation of the peritoneum that lines the abdominal organs)
Name the divisions of the colon:
ascending, hepatic flexure, transverse, splenic flexure, descending, and sigmoid colon
Which areas of the colon are intra-peritoneal?
transverse and sigmoid
The transverse and sigmoid colons also contain:
mesocolons or folds of peritoneum, or mesentery, attached to the colon
Which divisions of the colon are considered retroperitoneal?
ascending, hepatic flexure, splenic flexure, and descending colon
The rectum lies just anterior to what two structures?
the sacrum and the coccyx
How long is the anal canal?
3 cm long
What is the external opening of the large intestine called?
anus
What is another name for the thickening of the inner circular layer of muscularis?
the internal anal sphincter
What type of muscle is the internal anal sphincter made up of? Is this muscle voluntary or involuntary?
smooth; involuntary
What type of muscle is the external anal sphincter made up of? Is this muscle voluntary or involuntary?
skeletal muscle; voluntary
What type of cells can be seen in the columnar mucosa of the large intestine?
goblet cells
True of false? The large intestine has thousands of villi along the wall that helps move food through the digestive tract.
false
The anal canal is lined with what type of tissue?
stratified squamous epithelium
What do the anal sinuses secrete?
mucous
This is the name of the line that runs just below the anal sinuses:
pectinate or dentate line
What type of sensory innervation is seen below the pectinate line? above?
somatic (voluntary); visceral
What part of the anal canal can cause hemorrhoids?
the superficial venous plexuses
Is the outer longitudinal muscle complete?
yes the outer muscularis is complete
Approximately how many species of bacteria exist in the colon? What are these referred to as?
>700; bacterial flora
Are the bacteria in the colon harmful?
if they remain in the lumen, no
Which vitamins do the bacteria in the colon produce? What do they help with?
Vitamin B and vitamin K; used by the liver to synthesize clotting factors
How long does it take food to pass through the large intestine?
12-24 hours
Is there any chemical digestion in the colon? What's absorbed here?
no; vitamins and water
True or false: The colon is essential to life.
False
Name the contractile waves in the large intestine. How are they activated?
mass movements; by food entering the stomach
How often do mass movements occur?
3-4 times/day
When mass movements are stimulated by food entering the stomach, we refer to this as the:
gastrocolic reflex
These are the small pouches of mucosa which protrude through the muscularis of the colon wall:
diverticuli
A person who has diverticuli has ___________ (condition). This is caused by what?
diverticulosis

constipation
What is the name for an infected diverticulum?
diverticulitis
What do feces consist of?
undigested food residue, mucous, sloughed epithelial cells, bacteria, and water
When mass movements move feces into the rectum, dilation stimulates the :
defecation reflex
What parts of the colon contract during the defecation reflex? What relaxes?
The sigmoid colon and the rectum contract, the internal anal sphincter relaxes
Anything that increases the speed of passage through the large intestine will cause:
diarrhea
Inflammation of the mucosa in the large intestine will ultimately cause a person to have:
diarrhea (from decreased water absorption)
Anything that slows the passage of food through the large intestine will cause:
constipation
What usually causes constipation?
a lack of fiber in the diet
What other factors may cause constipation besides lack of fiber?
medications, stress, and a lack of exercise
What is the name for the inflammation of the GI mucosa?
gastroenteritis
What is the name for the inflammation of the gallbladder?
cholecystitis
Is it common to see the early stages of GI cancer? why or why not?
no; the diameter of the tract is large
Where do most metastases travel to once cancer has metastasized in the large intestine?
to the liver
Colon cancers originate from:
benign polyps
How are benign polyps removed?
by colonoscopy
Where does the celiac trunk branch from?
the aorta
What three branches does the celiac trunk divide into?
the common hepatic, the splenic, and the left gastric arteries
What does the common hepatic artery divide into?
the gastroduodenal artery and the proper hepatic artery
What organ(s) does the gastroduodenal artery supply?
the stomach, the duodenum and the pancreas
What organ(s) does the proper hepatic artery supply?
the liver
The splenic artery supplies which organs?
the spleen, pancreas, and stomach
The left gastric artery supplies blood to what organs?
the proximal stomach and distal esophagus
The superior mesenteric artery branches from the _________ and passes just inferior to the ________
aorta, pancreas
Where does the superior mesenteric artery enter?
the mesentery of the small intestine
What sections of the digestive tract does the superior mesenteric artery supply?
the duodenum, jejunum, ileum, and first half of the small intestine
What artery branch supplies the appendix and cecum?
the ileocolic branch
What section does the right colic branch supply? the middle colic?
ascending colon; the transverse colon
What supplies the distal half of the large intestine?
the inferior mesenteric artery
The left colic supplies what sections? the sigmoidal branch?
the descending colon; the sigmoid
What supplies the rectum with blood?
the superior rectal branch
All of the veins coming from the digestive organs come together to form the:
hepatic portal vein
The hepatic portal vein delivers blood to what organ? And what system is this a part of?
the liver

the hepatic portal venous system
After leaving the liver, the blood then passes through the ______ _____ which drain into the ________ ________ _______
hepatic veins

IVC (inferior vena cava)
Veins are named according to the corresponding ______ that supplies the organ
artery