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21 Cards in this Set
- Front
- Back
Aminoglycosides MOA
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Inhibit bacterial RNA synthesis - bactericidal
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Aminoglycosides adverse events
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Nephrotoxicity - increase in BUN and SCr
Ototoxicity |
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Aminoglycoside Examples
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Amikacin, Gentamicin, Neomycin, streptomycin
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Penicillins MOA
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Inhibit cell wall synthesis by binding PBPs - bactericidal
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Penicillin Adverse events
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GI, Allergic, Hypokalemia
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Cephalosporins MOA
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Inhibit mucopeptide synthesis in bacterial cell wall
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Cephalosporins Adverse Drug events
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Hypersensitivity, GI, Seizures, C. Diff colitis
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Fluoroquinolones MOA
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inhibit bacterial DNA topoisomerase
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Fluoroquinolones Adverse drug events
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GI, CNS, QT prolongation
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Fluoroquinolones examples
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Ciprofloxacin, Levofloxacin, Oflaxacin
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Fluoroquinolones Counseling
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Don't take antacints, calcium, magnesium, iron at least 2 hour after each dose
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Macrolides MOA
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Inhibit RNA synthesis
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Macrolides ADEs
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GI, QT prolongation, ototoxicity
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Macrolides examples
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Azithromycin, clarithromycin, erythromycin
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Tetracyclines Spectrum of Activity
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Respiratory infections, genital infections
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Tetracyclines counseling
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Administer with food
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Tetracyclines ADEs
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Photosensitivity reactions
Contraindicated in pregnancy, and children Hepatotoxic GI intolerance Antacids decrease GI absorption |
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Tetracyclines examples
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Doxycycline, Minocycline, Tetraycycline
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Sulfonamides MOA
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Interfere with folic acid synthesis
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Sulfonamides ADEs
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rash, urticaria
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Sulfonamides examples
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Sulfamethizole, sulfamethoxazole
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