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8 Cards in this Set
- Front
- Back
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What is Virchow's Triad?
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It is a recognized triad of conditions that increase the chance of clot development. It is comprised of damage to venous endothelium, blood stasis, and hypercoagulability.
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What is the usual focus when treating arterial clots versus venous clots?
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Arterial - They are typically platelets surrounded with a fibrin sheath.
Venous - They are usually RBCs with a fibrin sheath. |
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What are some conditions that can cause blood clots to form?
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Surgery - Can cause venous stasis
Atrial Fib - A clot in the lt atrium can travel to the lt ventricle and on to the brain Polycythemia - Can come from COPD or genetic causes |
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What is the general mechanism of anticoagulants?
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They prevent clot formation and extension and allow the body's natural mechanisms to break down any existing clots.
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What is the general mechanism of antiplatelet drugs?
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They interfere with platelet activity to reduce clot formation.
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What is the general mechanism of thrombolytics?
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They dissolve existing blood clots, but carry the highest risk of bleeding complications.
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When and how are thrombolytics usually given?
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They are given over a short period of time via IV infusion, usually in critical care areas like ICU, ED, cath lab, etc.
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What are the 3 medications we studied that are anticoagulants?
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Heparin
Low Molecular Weight Heparin (LMWH) - enoxaparin sodium (Lovenox) Warfarin (Coumadin) |
