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8 Cards in this Set

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  • Back
What is Virchow's Triad?
It is a recognized triad of conditions that increase the chance of clot development. It is comprised of damage to venous endothelium, blood stasis, and hypercoagulability.
What is the usual focus when treating arterial clots versus venous clots?
Arterial - They are typically platelets surrounded with a fibrin sheath.
Venous - They are usually RBCs with a fibrin sheath.
What are some conditions that can cause blood clots to form?
Surgery - Can cause venous stasis
Atrial Fib - A clot in the lt atrium can travel to the lt ventricle and on to the brain
Polycythemia - Can come from COPD or genetic causes
What is the general mechanism of anticoagulants?
They prevent clot formation and extension and allow the body's natural mechanisms to break down any existing clots.
What is the general mechanism of antiplatelet drugs?
They interfere with platelet activity to reduce clot formation.
What is the general mechanism of thrombolytics?
They dissolve existing blood clots, but carry the highest risk of bleeding complications.
When and how are thrombolytics usually given?
They are given over a short period of time via IV infusion, usually in critical care areas like ICU, ED, cath lab, etc.
What are the 3 medications we studied that are anticoagulants?
Low Molecular Weight Heparin (LMWH) - enoxaparin sodium (Lovenox)
Warfarin (Coumadin)