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7 Cards in this Set

  • Front
  • Back

Unfractionated heparin mechanism

Inhibits antithrombin III—>Inactivates thrombin & factor Xa

Antidote for UFH

Protamine

LMWH(Enoxaparin) mechanism

Indirect thrombin inhibitor & inactivates factor Xa

Warfarin mechanism

Inhibits synthesis of Vit K dependent clotting factors - II, VII, IX, X, protein C & S

Aspirin mechanism

Inhibits platelet-generation of thromboxane A2 —> antithrombotic effect.

Clopidogrel mechanism

Inhibits platelet activation & aggregation by irreversibly binding to P2Y12 class of ADP receptors on platelet

Tranexamic acid mechanism

Competitively inhibits activation of plasminogen to plasmin (anti-fibrinolytic).