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6 Cards in this Set
- Front
- Back
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methotrexate |
Antimetabolite
Cell cycle specific blocks dihydrofolateReductase (DHFR) |
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etoposide |
DNA topological Cell cycle specific prevents DNA coiling |
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vincristine |
Mitotic-blocking alkaloid (blocks MT polymerization in M phase) Cell cycle specific |
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doxorubicin |
Intercalating antibiotic Cell cycle non-specific binds to DNA, blocks replication and transcription |
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cyclophosphamide |
Alkylating agent (mustard gas) Cell cyclenon-specific damages (alkylates) DNA... triggers cell death |
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tamoxifen |
Hormonal antagonist Cell cyclenon-specific analogue of estrogen reduces promotion of cell division |
