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50 Cards in this Set
- Front
- Back
Calcium chelator
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Tetracycline
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Brown teeth
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Tetracycline
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Gray-baby syndrome
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Chloramphenicol
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Oto- and nephrotoxicity
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Vancomycin, aminoglycosides
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Optic neuritis
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Ethambutol
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Polyarthralgia
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Pyrazinamide
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Induces cytochrome P450
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Rifampin
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Red-man syndrome
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Vancomycin
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Pseudomembranous colitis
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Clindamycin
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Kernicterus
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Sulfonamides
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Megaloblastic anemia (supplement with vitamin B6)
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Trimethoprim-sulfamethoxazole
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Cartilage damage, tendonitis
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Fluoroquinolones
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Orange bodily fluids
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Rifampin
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Fast vs. slow acetylators
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Isoniazid
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Infusion-related toxicity
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Amphotericin B
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D-Ala-D-Ala
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Vancomycin
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PBP3
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Aztreonam
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Blocks peptidyltransferase
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Chloramphenicol
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Blocks peptide bond formation
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Clindamycin
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Blocks ribosomal translocation by preventing exit of tRNA
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Macrolides
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Inhibits initiation complex, causes mRNA misreading, blocks translocation
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Aminoglycosides
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Blocks tRNA binding to ribosome
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Tetracycline
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Bactericidal for H. flu, S. pneumo, N. meningitidis
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Chloramphenicol
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Blocks initiation step of protein synthesis
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Linezolid
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PABA analogue
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Sulfonamides
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Prevents synthesis of dihydrofolic acid
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Sulfonamides
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Inhibits dihydropteroate synthetase
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Sulfonamides
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Prevents synthesis of tetrahydrofolic acid
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Trimethoprim
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Inhibits dihydrofolate reductase
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Trimethoprim
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Resistance is due to rRNA methylation
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Clindamycin, macrolides
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DNA gyrase, topoisomerase IV
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Fluoroquinolones
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RNA polymerase
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Rifampin
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Inhibits mycolic acid synthesis
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Isoniazid
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Inhibits arabinogalactan synthesis
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Ethambutol
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Inhibits microtubule function
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Griseofulvin
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Inhibits beta(1,3)D-glucan synthetase
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Caspofungin
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Binds ergosterol
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Amphotericin B, nystatin
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Inhibits lanosterol demethylation by cytochrome P450
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Azoles
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Inhibits thymidylate synthase
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Flucytosine
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Used to treat cryptococcal meningitis
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Flucytosine
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Used for meningococcal prophylaxis
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Rifampin
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Used to treat Pseudomonas infection in CF patients
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Fluoroquinolones
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Used to treat nocardiosis
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Sulfonamides
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Used to treat VRE, MRSA, PRSP
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Linezolid
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Used to treat C. perfringens and B. fragilis
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Clindamycin
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Used to treat Mycoplasma pneumoniae
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Tetracycline
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Used to treat chlamydia
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Tetracycline
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Used to treat Legionella
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Macrolides
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Used to treat gonorrhea
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Ceftriaxone
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Used to treat H. flu meningitis
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Chloramphenicol
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