Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/26

Click to flip

26 Cards in this Set

  • Front
  • Back

Sulfa Drugs

Block synthesis of folic acid, thus nucleic acids





Isonazid

Nictoamide analog


Only effects mycobacterium


Effects mycologic synthesis (part of cell wall)


TB





Quinolones

interferes with DNA Gyrase


Prevents supercoiling


Floroquinolones- have added floro group


Treat UTI's


agricultural use





Ciproflaxin

(Quinolone)


Anthrax



Moxiflavocan

(Quinolone)


TB



Nucleic acid analogs

Prevent Replication, Transcription, Translation



Acyclovir, Ganoclovir

(Nucleic acid analog)


Herpes

B-Lactam

Cell wall inhibitor


Binds to inactive transpeptidase


Prevents cross bridge formation



Penicillin

(B-Lactam)


Natural types G and V





Ampicillin

Resistant to B-Lactamases

Methocillin

(Penicillin) MRSA is Resistant





Augmentin

Amoxicillin + Clavolanic acid

Cephalosporins

B-lactam ring and Dihydrodiol ring


More resistant to B-lactamase


4 Generations


1. Just G+


2. G-


3. Peseudomonas


4. Oral

Ceftriaxone

(Cephalosporin)


gonorrhea

Carbapenems

Synthetic B-Lactam



Doripenem

(Carbapenem)


Pseudomonas Aerogonia

Bacatracin

(Cell Wall inhibitor)


Topical Antibiotic


Streptococcus, and Staphylococcus



Vanocymicin

(Cell Wall inhibitor)


Glycopeptide from amalcytase

Aminoglycosides

amino sugars with glycidic linkages


Kanamyosin, Centramycin, neomycin


Change shape of 30S subunit cause mRNA misreading


Harmful to Host

Macrolides

Large lactose rings connected to sugars


Binds to 50S subunit, prevents movement of mRNA


Erythromycin, Z-Pak,

Tetracyclines

4 rings, lots of modification possible


From Streptomyces


Interfere with tRNA attachment

Chloramphnicol

Binds to 50S subunit inhibits peptide bond formation


Supressed bone marrow formation

Oxazolidinones

Synthetic


Binds to 50S prevents 30S from attaching


Effective against MRSA

Daptomycin

(Plasma Membrane Injury)


Puts pores in membrane, lyses cell

Polymyxin b lipopeptide

(Plasma Membrane Injury)


Pseudomonas


With Bacatracin makes neosporin

platensimycin

Fatty Acid Inhibition


MRSA


New Class of Drug


Unique mode of action