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28 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Mechanism of Antihistamines |
H1 Histamine Receptor Antagonists |
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Uses of Antihistamines |
N/V Associated with motion sickness Other vestibular disorders |
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Side Effects of Anti-Histamines |
Drowsiness Antimuscarinic Side Effects |
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3 Antihistamines |
Cinnarizine Cyclizine Promethazine |
Can Cure Puking |
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Antimuscarinic Mechanism |
Muscarine Receptor Antagonists Block muscarine receptor-mediated impulses from labyrinth & visceral afferents |
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Example of Antimuscarine |
Hyoscine Hydrobromide |
Hi Bro |
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Uses of Antimuscarine Drug |
Motion Sickness |
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Advantages of Antimuscarine Example |
Can be given in patch or tablet form |
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Side Effects of Antimuscarine |
Dry mouth Constipation Transient Bradycardia |
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Dopamine Antagonists - Where do they act? |
CTZ |
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Uses of Dopamine Antagonists? |
CTZ-Triggered Vomiting (not stomach-induced) |
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Class of Dopamine Antagonists that were used for mental patients? |
Pheonthiazines - Used as neuroleptics/antipsychotics (Used in Schizophrenia etc.) |
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Examples of Phenothiazines |
Chlorpromazine Prochlorperazine Trifluoperazine Perphenazine |
'Azine' |
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Other Dopamine Antagonists |
Domperidone Metoclopramide (given in pregnancy) |
Champagne Met Jurgen |
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5HT3 Antagonist Mechanisms |
Block 5HT3 Receptors in CNS & GI Tract |
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5HT3 Antagonist Uses |
Preventing Cytotoxic-induced N/V Post-operative N/V Short-Term Use Cancer Patients |
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5HT3 Antagonist Examples |
Dolasetron Granisetron Ondansetron Palonosetron |
'Setron' |
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Neurokinin-1 Receptor Antagonsist Mechanism |
5HT3 Antagonist |
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What are Neurokinin-1 Receptor Antagonists Used With? |
Adjunct to Dexamethasone |
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Examples of Neurokinin-1 Receptor Antagonists |
Aprepitant Fosaprepitant |
'Prepitant' |
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Synthetic Cannabinoids Uses |
N/V by Chemo & unresponsive to other anti-emetics |
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Example of Cannabinoid |
Nabilone |
'nab' |
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Side Effects of Cannabinoids |
Dizzy & Drowsy |
Cannabis effects |
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Steroid Example |
Dexamethasone |
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Uses of Dexamethasone |
Palliative Shrinks malignancies etc. to relieve pressure Cancer Chemo-induced N/V Adjunct to other anti-emetics |
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Neuroleptic examples |
Haloperidol Levomepromazine |
Master Chief + Toby + Doll |
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Advantages of Neuroleptics |
Can be used in syringe drivers Can be used at home |
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Uses of Neuroleptics |
Palliative Patients |
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