Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
6 Cards in this Set
- Front
- Back
MOA for Quinolones (fluoroquinolones)
|
- bactericidal
- inhibits DNA enzymes (topoisomerase,,, gyrase) that are needed for DNA replication |
|
indications for Quinolones (fluoroquinolones)
|
- Very broad spectrum of activity
- gram pos - gram neg - LIMITED/poor anerobic coverage - activity against enterococci - activity against P. aeruginosa (ciprofloxacin) |
|
Name some (Fluoro)Quinolones
|
ciprofloxacin
levofloxacin ofloxacin gemifloxacin moxifloxacin norfloxacin |
|
which (Fluoro)Quinolone is only used for UTI?
|
norfloxacin
|
|
which (fluoro)Quinolone has no activity against psedomodas?
|
levofloxacin
|
|
What are the common AE of (fluoro)quinolones?
|
- Arthropathy --affects connective tissue --not used in children
- GI & hypersensitivity rxns |