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17 Cards in this Set

  • Front
  • Back

Category A

No demonstrated risk of abnormalities

Cat as gory B

No demonstrated risk in human or animal studies

Category 3 pregnancy

Significant testing has not been done.

Short duration

20-40 minutes with pulp all duration

Intermediate –

up to 70 minutes

Long duration

Up to 6 hours

Soft tissue anethesia

Lasts longer

Lidocaine

The “gold standard”


Amide


Reliable


Rapid onset


Rare hypersensitivity, no


cross-allergenicity


Pulpal duration – 1 hour,


soft tissue – up to 5 hours


Anticonvulsant properties


Depresses the excitability of


the cortical neurons, raises


seizure thresholds


Twice as potent as procaine


(p. 56)


Twice as toxic as procaine


and prilocaine


Lidocaine


Onset of action 2-3


minutes.


Pregnancy category B


Strong vasodilating effects


– short duration with no epi


Vasoconstrictor added –


more profound and durable


anesthesia

Lidocaine plain

Very short


5-10 min pulpal


60-120 min soft tissue

Lidocaine with EPI

Intermediate


Pulpal 60 minutes


Soft tissue 180-300 min

Lidocaine duration

PLAIN with EPI


Very short Intermediate


5-10 min pulpal 60 minutes


This characteristic differs the most. The more lipid

Lidocaine potency

2 X procaine (predecessor)


Equal to mepivacaine and prilocaine


2/3 that of articaine


¼ that of bupivacaine


Extended but not excessive duration, profound anesthesia

Lidocaine maximum dose

500 mg with


epinephrine


300 mg(plain, with no


epi; again, not available


in dentistry)

Lidocaine toxicity

Relative Toxicity


Twice that of PROCAINE and PRILOCAINE


More toxic to the CNS and CVS than prilocaine


Far less than prilocaine in patients with methemoglobenemia


Similar to MEPIVACAINE and ARTICAINE


Greater overdose-inducing potential than articaine Why?


Far less than BUPIVACAINE


This toxicity value assumes that the drug has not been

Lidocaine is metabolized in

The liver by acidases and amidases


Hydrolysis 1/3 of lidocaine is eliminated


Lidocaine excretion

Less then 10% is excreted by kidney unchanged


Low urine ph

Vasoactivity

Potent vasodilator - short duration if no vasoconstrictor is present.