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30 Cards in this Set
- Front
- Back
Relative Performance Length-Specific
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speed/body length (1/s)
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small organisms
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viscosity dominates
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large organisms
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inertia dominates
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is metabolic rate directly proportional to body mass?
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NO
Log metabolic rate vs. Log body mass --> slope of line is not 1 |
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Scaling - Geometrical Similarity
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Organisms are similar if the large one is an enlarged picture of the small one.
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Scale factor
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λ = length of large/length of small
ratio of any two corresponding lengths is a CONSTANT |
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why do we use log axes to compare surface area to volume?
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1. straight line easier to use
2. allows broad ranges to be compared |
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scaling equation
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S = a * V^(2/3) --> log(S) = (2/3)*log(M) + log(a) --> line! (y=mx+b)
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allometric scaling
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non-geometric scaling
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vasculature model
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natural selection has tended to maximize both metabolic capacity, by maximizing the scaling of exchange surfaces, and internal efficiency, by minimizing the scaling of transport distances + times
REJECTED - actually non-linear |
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utility of allometry
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1. see general patterns in morphological/physiological traits
2. Predict unknown values 3. Generate hypotheses upon which to test explanations of function |
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scaling of time
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time = M^(.25)
period of heart beat, period of respiration, time of muscle contraction, time to clear substance from kidney, time to reproductive maturity, gestation time |
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what is mass independent?
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heart beats per lifetime
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the rate of life can be a function of ___________
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temperature
double rate for every 10 degrees C increase in temperature |
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afferent nerve
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sensory input (peripheral NS to central NS [brain/spinal cord])
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efferent nerve
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motor output (central NS to peripheral NS [muscles/glands])
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integration
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happens at dendrites + soma
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signal conduction
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happens at axon
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spike initiation
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happens at axon hillock
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transmitter secretion
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happens at axon terminal
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interneuron
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conduction among neurons (in CNS), integrate + store information from other neurons
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neurosecretory
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receive stimulus and secrete hormones into blood
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ganglia
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cluster of nerve cell bodies
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what determines resting membrane potential?
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must consider permeability
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resting membrane potential determined by...
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K equilibrium potential
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major ions in mammalian excitable tissue
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K+, Na+, Cl-
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conductance
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g = 1/R
conductance ~ permeability |
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Hodgkin cycle
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opening of Na+ channels in membrane --> increased membrane Na+ permeability --> increased flow of Na+ into cell --> depolarization -->
(positive feedback cycle) |
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voltage sensitive gates
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1. activation gate opens
2. inactivating particle blocks channel 3. activation gate closes |
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relative refractory period
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more current needed to reach threshold, reduced amplitude
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