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133 Cards in this Set

  • Front
  • Back
Salivary ____ acts on starch to produce____.
amylase, maltose (disaccharide)
Salivary _____ acts on maltose to produce ______.
maltase, glucose
glucose-glucose =
maltose
chymosin
curdles milk (usually in young cattle so it stays longer in the stomach_
Gastric ____ acts on proteins to produce ______
pepsin, oligopeptides
Pepsin secreted by
Chief Cells
amylases act on:
starch to produce disaccharides
peptidases act on:
proteins to produce oligopeptides
lipases act on:
fats to produce fatty acids, glycerol and monoglycerides
intestinal peptidases act on:
oligopeptides to produce amino acids
Disaccharidases:
maltase, sucrase, lactase
maltase, sucrase and lactase act on disaccharides to produce:
glucose, fructose and galactose
CCK (cholyscystokinin)
stimulates gallbladder to contract and releases digestion enzymes. (is a hormone)
Polypeptides are ____ soluble
water
Steroids are _____ soluble
fat
only molecules that are ______ ______ can enter the cell
fat soluble
Insulin will prevent ______
glycogenolysis
Glucagon and Epinephrine favor _____
glycogenolysis
DNA to MRNA =
transcription (nucleus)
MRNA to Protein =
Translation (cytoplasm)
Gastrin:
stimulates acid secretion, stimulates release of: peptides, amino acids
Secretin:
stimulates pancreatic bicarbonate secretion. stimulates release of fat.
Gastric Inhibitory Polypeptide (GIP)
stimulates insulin release
Somatostatin:
inhibits acid secretion
Histamine:
stimulates gastric acid secretion
DM and CP
Dry Matter, Crude Protein
CF and EE
Crude Fiber and Ether Extract
ADF and NDF
Acid Detergent Fiber and Neutral Detergent Fiber
ADF has ____ and NDF does not:
hemicellulose
ADIN, TDN and NFE
Acid Detergent Insoluble Nitrogen, Total Digestible Nutrients and Nitrogen Free Extract
calculation for NFE:
100 - (Moisture + CP + EE + CF + Ash)
Multiply N by ___ to get % CP
6.25
Difference between NDF and ADF
ADF removes hemicellulose
example of NDF
plant cell wall components
Lignin:
has no nutritional value to animals
DM basis is what percentage ?
100%
Air Dry basis is what percentage?
90%
As fed basis percentage is?
20-100% water, depends on feedstuff
When converting to "As-Fed" to DM, nutrient concentration will _____, weight will ____
go up, go down
when converting DM to As-Fed, nutrient concentration will ____ and weight will _____.
go down, go up
To change PPM to %:
divide by 10,000 (move decimal 4 places to the right)
50,000 ppm = 5%
6% = 60,000ppm
mg/kg is:
the same as mg/million mg or PPM
mg/lb =
1lb = 453,600mg, so same as 453,600 mg
convert mg/lb to PPM
multiply by 2.205
convert mg/lb to %
multiply by 2.205, then divide by 10,000
convert PPM to mg/lb
divide by 2.205
convert % to mg/lb
multiply by 10,000, divide by 2.205
In vivo:
in the animal
In situ:
local (example, the cannula)
In vitro:
in glass/lab
TDN is derived by adding together:
DCP (digestible crude protein), DCF (digestible crude fiber), Digestible NFE, Digestible Crude Fat (EE x 2.25)
Lipids have ____ x the energy value of an equal weight of carbohydrate and protein.
2.25
What does TDN not include:
digestible mineral matter (ash)
Feeds high in fat will sometimes exceed 100% because:
digestible fat is multiplied by 2.25
Unless the DM of a feed is ____, it can have no TDN value
digestible, so foods high in fiber are low in digestibility and have low TDN
more digestible fat _____ the TDN value
higher
Energy Disposition:
Gross Energy (fecal energy) --- Digestible Energy (urinary and gas energy) ---- Metabolizable energy (heat increment) --- Net energy (available for animal)
Net Energy:
portion of metabolizable energy that may be used for work, growth, fattening, fetal development, milk production and/or maintenance.
ME-HI (heat increment) =
NE (net energy)
Carbohydrates contain ___ ___ and ___, with ___ and ___ in the same proportion as H2O.
C, H, O, H O
The main source of energy for an animal:
carbohydrates
Simple sugar formula
C6H12O6
formed in plants by:
photosynthesis:
Glucose is a _______ and is found primarily in:
monosaccharide: syrup and blood
Glucose is sometimes referred to as:
dextrose
Fructose is found in: ______ and ____ and is the _______ of all sugars.
ripe fruits and honey: sweetest
Galactose is found in
Milk
Disaccharides all have the formula:
C12H22O11, formed by two monosaccharides
Sucrose:
disaccharide, hydrolyzed by glucose and fructose. Has alpha 1-4 bond.
Maltose
disaccharide, hydrolyzed to glucose by maltase.
Lactose:
disaccharide: hydrolyzed by lactase to glucose and galactose.
Oligosaccharides:
short chains of monosaccharides, < 10
Polysaccharides:
complex carbohydrates with chemical formula of: C6H10O5
Polysaccharide: Starch:
major plant storage form of glucose. Occurs as Amylose (straight chains) and Amylopectin (highly branched). Have α 1-4 bonds, which are hydrolyzed by amylases
Polysaccharides broken down to ____ broken down to ____ broken down to ____ before digestion
oligosaccharides, disaccharides, monosaccharides
Glycogen: Polysaccharide:
sometimes referred to as "animal starch". Produced by the liver and is the PRIMARY CARBOHYDRATE RESERVE IN ANIMALS.
Glycogen is hydrolyzed entirely to
glucose
Pancreatic amylases do not work on:
α 1-4 bonds
Polysaccharide: Hemicellulose:
lies chemically between starch and cellulose. More digestible than cellulose, but less digestible than sugars and starch
Polysaccharide: Cellulose:
principal constituent of cell wall of plants. Low in digestibility. Linked by β 1-4 bonds (only digestible by ruminants and hind gut fermenters).
Cellulose is hydrolyzed to:
glucose
Polysaccharide:Lignin:
not a true carbohydrate. Too much C, H and O are not in right proportion. Found in overmature hays
Differences between Large and Small Intestine absorption of Carbohydrates: Type of digestion:
Large: microbial
Small: enzymatic
Differences between Large and Small Intestine absorption of Carbohydrates: End product
Large: VFA's
Small: glucose
Differences between Large and Small Intestine absorption of Carbohydrates: Absorption:
Large: passively diffused into bloodstream
Small: absorbed using ATP
VFA's are absorbed in the:
rumen NOT small intestine
Ruminants do not have this enzyme:
salivary amylase
Pancreatic amylase:
hydroyzes α 1-4 bonds, produces monosaccharides, disaccharides and polysaccharides
Digestion in the small intestine is mediated by enzymes lining the :
brush border region
Disaccharides are converted by ______ enzymes to monosaccharides
brush border
sucrose broken down by ______ to _______ and _______
sucrase, glucose and fructose
Maltose broken down by _______ to ________ and _________
maltase, glucose and glucose
Lactose broken down by _______ to ________ and ________
lactase, glucose and galactose
Volatile Fatty Acids (VFA's)
Propionate, Butyrate and Acetate
Cellulase is capable of hydrolyzing _________
β 1-4 linkages (like in cellulose that hind gut and ruminants eat)
Monosaccharides are absorbed primarily in the:
duodenum and jejunum
SGLT
sodium dependent glucose transporter - found in intestinal lumen
GLUT2
facilitated glucose transporter (across plasma membranes)
Insulin influences:
rate of transport
In ruminants: most carbohydrates are fermented by:
microbes before they are exposed to gastric and small intestine enzymes
In ruminants: almost all carbohydrates are fermented in the:
rumen
Cellulolytic Bacteria: prefer ____ pH
prefer 6-7 pH, use N as NH3, produce Acetate, propionate and little butyrate and CO2. Predominate in animals fed high roughage diets
Amylolytic Bacteria
digest starch, prefer pH 5-6, utilize N as NH3 or peptides, produce propionate, butyrate and sometimes lactate. Predominate in animals fed grain diets
Ruminant small intestine:
secrete digestive enzymes, digestive secretions from pancreas and liver, further digestion of carbs,end product glucose
Ruminant Cecum and Large intestine:
Bacterial population ferments the unbabsorbed products of digestion, absorption of H2O and VFA's, end product VFA, passive
Carbohydrate digestion rate
Sugars (fastest), Starch, Cellulose (slowest)
VFA's are absorbed passively from the rumen to portal blood and provide __________
70-80% of the ruminants energy needs
Acetate:
energy and fatty acid synthesis
Propionate:
energy and gluconeogenic glucose synthesis
Butyrate:
energy and rumen epithelial cells convert butyrate to ketone
Cells use most of the butyrate ______________________
for their own energy needs
Acetate and Propionate are exported to _______
blood
High forage diet =
high acetate production
High grain diet =
high propionate production
Bicarbonate comes from:
saliva --- if fed high grain, less saliva produced, so less bicarbonate and lower pH
Propionate is reserved for:
gluconeogenesis
Acetate is the major substrate for:
lipogenesis - hence importance of adequate fiber in dairy diets to maintain milk-fat levels
Why is there less fluctuation of glucose in ruminants?
eat more constantly, continuous VFA production, continuous digesta flow, continuous gluconeogenesis
Glucose may be CATabolized to:
pyruvate or lactate by glycolosis
Glucose may be POLYmerized and:
stored as glycogen in the liver and muscle
Glucose may be OXIdized via:
pentose-phosphate pathway
Glycolosis consists of:
10 sequential reactions, that convert glucose to tow molecules of pyruvate
aerobic glycolosis
pyruvate degraded to H2O and CO2
Glycogen is a _____ branched ______ of _______.
highly, polymer, glucose
In the liver glycogen acts as:
a buffer for regulating glucose levels between meals
In the muscle glycogen acts as:
a store of glucose, rapidly metabolized to provide energy
Glycogenesis:
blood glucose converted to glycogen
_____ is the rate limiting component in golycogenesis
glycogen synthase
Glycogen Metabolism:
well-fed state
glycogen synthesis: increased
Glycogen Metabolism:
fasting
glycogen synthesis: decreased
Glycogen Metabolism:
hyperglycemia and hypoglycemia
glycogen synthesis: increased and decreased
Glycogen Metabolism:
Elevated insulin:
Elevated Glucagon, Epinephrine and adenosine
glycogen synthesis: increased with insulin, decreased with the other three
Glycogen Metabolism:
Enzyme phosphorylation: glycogen synthase, glycogen phsphorylase
Glycogen synthesis: decreased and increased