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58 Cards in this Set

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  • Back
  • 3rd side (hint)
3 Functions of Blood
1. Transport of Various Substances
2. Regulates Several Life Processes
3. Protection against Diseases
1. Carries nutrients from G.I. tract to cells of the body, moves oxygen from lungs to body cells and hormones from glands to body cells.
2. Regulates pH, adjusts body temp and blood pressure
3. Blood clotting and helps fight disease or avoid diseases.
Physical Characteristics of Blood
1. Temperature- 38°C (100.4°F)
2. pH Range- 7.35 to 7.45
2 Components of Blood & Percentage Each Make Up
Plasma- 55%
Formed Elements- 45%
What makes up Blood Plasma?
91.5% Water
8.5% Solutes
The Principal Solutes Include What?
Globulins, Albumins, & Fibrinogens
Where are Globulins Produced? And What Do They Do?
Produced in the liver & Help attack viruses and bacteria
Where are Albumins produced? And what do they do?
Produced by the liver & Smallest and most numerous & Transports substances
Where is Fibrinogen produced? And what does it do?
Produced in the liver & Plays essential role in blood clotting
3 Principle Components of Formed Elements
1. Erythrocytes (RBC's)
2. Leukocytes (WBC's)
3. Thrombocytes (Platelets)
Measures percentage of RBC's in packed whole blood
Nurses check this for anemia
Process by which the formed elements of blood develop in Red Bone Marrow
Blood cells are formed by these cells
Pluripotent Stem Cells
2 Types of Pluripotent Stem Cells
Myloid Stem Cells
Lymphoid Stem Cells
Gives rise to RBC's, Platelets, and all WBC's (except for lymphocytes)
Myloid Stem Cells
Give rise to Lymphocytes
Lymphoid Stem Cells
Myloid Stem Cells differentiate into these 2 types of cells
Progenitor Cells
Precursor Cells
These develop into a BLAST cell which will mature into a CYTE
Precursor Cells
These develop into CFU's ( Colony Forming Units). Which are the source of platelets
Progenitor Cells
These develop into a blast cell which then matures into a cyte
Precursor Cells
These differentiate into Pre-B Lymphocytes and Pro-T Lymphocytes which are your disease fighters
Lymphoid Stem Cells
Hormone that regulates the differentiation and proliferation of all the blood cells
Hemopoietic Growth Factor
Increases the number of red blood cell precursors in red bone marrow
Increases the number of platelet precursors from megakaryocytes
Increase the number of WBC precursors
Function of RBC's
Transports gases
How does RBC's transport gases?
These proteins readily attach to O2 and Carbon Dioxide to help transport gases through the blood
How long do RBC's live?
120 days
Protein that transports iron in blood
Protein that store iron
Divides several times and near the end of development it ejects its nucleus.
becomes a reticulocyte
2 Principal Types of WBC's
3 Types of Granular Leukocytes (WBC)
3 Types of Agranular Leukocytes
How long do WBC's live?
A few hours to a few days
Increase in the number of WBC's
Not a pathology
Decrease or abnormally low level of WBC's
Is a pathology
Process by which WBC'S leaves the bloodstream and does so by squeezing between cells
Attraction for which a WBC has for an injury or disease
Combat the effects of histamine in allergenic reactions and phagocytizes antigen body complexes
Develop into mast cells that liberate heparin, histamine, and serotonin in allergic reactions. Intensify inflammatory response
Produces itself to an antigen and forms antibodies
Destroys any foreign invader it comes in contact with
Life span of a platelet
5-9 Days
Cycle in which a platelet is formed
Myloid Stem Cell ---> CFU's ---> Megakaryoblast ---> Megakaryocyte ---> Platelet
Platelets help stop blood loss from damaged vessels by forming what?
Platelet Plug
Refers to the stoppage of bleeding
3 Mechanisms that reduces blood loss
1. Vascular Spasm
2. Platelet Plug Formation
3. Blood Clotting (Coagulation)
There are 13 Coagulation Factors. The first one being ______________ & The last one being ______________.
Fibrinogen & Fibrin Stabilizing Factor
As these factors increase they become stronger
Coagulation Factors
Bubble of air, fat from a broken bone or piece of debris that's transported by the bloodstream from the site of origin
Thrombus or Thrombosis
As a Thrombus is moving or if it gets lodged it is known as what?
People whose RBC'S have only antigen A has what blood type?
Type A
Those who only have Antigen B have what blood type?
Type B
Those who have both A & B Antigens have what blood type?
Type AB
Universal Recipients
Those who have neither Antigen A or B have what blood type?
Type O
Universal Donors
People whose RBC'S have Rh antigens are considered to be what?
People whose RBC'S lack Rh antigens are considered what?