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45 Cards in this Set
- Front
- Back
2 types of lymphatic system |
tissues and vessels |
|
macrophages |
in lymph nodes, engulf and destroy |
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lymphocytes |
white blood cell, kill stuff |
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spleen |
left, filters blood, destroys worn out blood cells |
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thymus |
low throat peaks at childhood destroys stuff |
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tonsils |
pharynx catch bacteria |
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peyers |
intestine destroy bacteria |
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innate |
nonspecific, first and second line stops pathogens |
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first line of defense |
skin mucous membrne and secretions |
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second line of defense |
phagocytes, antimicrobial proteins, inflammatory response |
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phagocytes |
2nd line, engulf and destroy (macrophage or neutrophil) lysozome broken down |
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nkc |
direct cell attack not specified notphagocytes attack membrane |
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inflammatory responseindicators |
redness heat swelling pain |
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inflammatory process |
alarm, release histamine and kinins, causes vessels to dialate, activate pain receptors, attract phagocytes and and white blood cells to area |
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chemotaxis |
cells follow chemical gradient to go help imflammatory response |
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inflammatory response helps |
not spread damage to other tissue, dispose of cell debris and pathogens, sets stage for repair |
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diapedesis |
neutrophils squeeze through capillary walls |
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how does heat help |
metabolic rate |
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monocytes become |
phagocytes (macrophages) |
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antimicrobial proteins |
eith attacks or hiders ability to reproduce |
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complement |
group of 20 plasma proteins circulate blood, fixed to foreign cell surface, MAC, produce lesions, opsinization |
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opsinization |
cause cell membranes to be sticky so can phagicytize |
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interferon |
help defend not infected cells by secreting proteins calle dinterferons, enter tissue cells and take over reproduction |
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fever |
pyrogens cause, increase metabolic rate, bacteria needs zinc and iron and liver and spleen take it away from them. |
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aspects of adaptive defense |
antigen specific, systemic (immunity can be everywhere), has memory |
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two arms of adaptive system |
humoral immunity (antibody mediated immunity) fluids, cellular immunity (cell mediated), lymphocyte cells themselves protect |
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antigen |
anything provoking immune response |
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2 lymphocytes |
b cells produce antibodies and oversee humoral immunity (bone marrow, t cells non antibody producing cell mediated arm (thymus) |
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macrophagess |
also present antigens so t cells recognize them, secrete cytokins |
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b cells become |
plasma or memory cells |
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infection |
natural active |
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mom |
natural passive |
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vccine |
art active |
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snake |
art passive |
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antibodies |
screted by b cells plasma cells, neu agluu bla bla |
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neutralization |
antobodies bind on exotoxins block harmfulness |
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agglutination |
clumping of foreign cells |
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precipotation |
both |
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killer t cells |
specialized in killing |
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helper t cells |
direct and manage where killers go cytotoxic |
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graves |
tyroid produces exess thyroxine |
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diabetes |
destroys pancreatic beta cells |
|
ra |
destroys joints |
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3 ways we disease |
1. instead of silenced or eliminated, b or t cells escape to rest of body 2. appearance in the circulation of self proteins that were not previously exposed to the immune system 3. cross reaction of antibodies produced against foreign antigens with self antigens. cause s rhumatic fever |
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aids affects |
helper t cells |