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45 Cards in this Set

  • Front
  • Back

2 types of lymphatic system

tissues and vessels

macrophages

in lymph nodes, engulf and destroy

lymphocytes

white blood cell, kill stuff

spleen

left, filters blood, destroys worn out blood cells

thymus

low throat peaks at childhood destroys stuff

tonsils

pharynx catch bacteria

peyers

intestine destroy bacteria

innate

nonspecific, first and second line stops pathogens

first line of defense

skin mucous membrne and secretions

second line of defense

phagocytes, antimicrobial proteins, inflammatory response

phagocytes

2nd line, engulf and destroy (macrophage or neutrophil) lysozome broken down

nkc

direct cell attack not specified notphagocytes attack membrane

inflammatory responseindicators

redness heat swelling pain

inflammatory process

alarm, release histamine and kinins, causes vessels to dialate, activate pain receptors, attract phagocytes and and white blood cells to area

chemotaxis

cells follow chemical gradient to go help imflammatory response

inflammatory response helps

not spread damage to other tissue, dispose of cell debris and pathogens, sets stage for repair

diapedesis

neutrophils squeeze through capillary walls

how does heat help

metabolic rate

monocytes become

phagocytes (macrophages)

antimicrobial proteins

eith attacks or hiders ability to reproduce

complement

group of 20 plasma proteins circulate blood, fixed to foreign cell surface, MAC, produce lesions, opsinization

opsinization

cause cell membranes to be sticky so can phagicytize

interferon

help defend not infected cells by secreting proteins calle dinterferons, enter tissue cells and take over reproduction

fever

pyrogens cause, increase metabolic rate, bacteria needs zinc and iron and liver and spleen take it away from them.

aspects of adaptive defense

antigen specific, systemic (immunity can be everywhere), has memory

two arms of adaptive system

humoral immunity (antibody mediated immunity) fluids, cellular immunity (cell mediated), lymphocyte cells themselves protect

antigen

anything provoking immune response

2 lymphocytes

b cells produce antibodies and oversee humoral immunity (bone marrow, t cells non antibody producing cell mediated arm (thymus)

macrophagess

also present antigens so t cells recognize them, secrete cytokins

b cells become

plasma or memory cells

infection

natural active

mom

natural passive

vccine

art active

snake

art passive

antibodies

screted by b cells plasma cells, neu agluu bla bla

neutralization

antobodies bind on exotoxins block harmfulness

agglutination

clumping of foreign cells

precipotation

both

killer t cells

specialized in killing

helper t cells

direct and manage where killers go cytotoxic

graves

tyroid produces exess thyroxine

diabetes

destroys pancreatic beta cells

ra

destroys joints

3 ways we disease

1. instead of silenced or eliminated, b or t cells escape to rest of body


2. appearance in the circulation of self proteins that were not previously exposed to the immune system


3. cross reaction of antibodies produced against foreign antigens with self antigens. cause s rhumatic fever

aids affects

helper t cells