Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
32 Cards in this Set
- Front
- Back
The ? response is a complex concert of reactions to injury
|
inlfammatory
|
|
The second line of defenses, are ? immune reactions and this includes ? (CIPI)
|
nonspecific
Complement Inflammation Phagocytosis Interferon |
|
The 5 classic symptoms of inflammation are ?(redness),?(heat),?(swelling/edema),?(pain),?
|
rubor
calor tumor dolor loss of function |
|
? are another component of nonspecific immunity and they can be exogenous or endogenous
|
pyrogens
|
|
? increases the rapidity of the host immune responses and reduces the viability of many microbial invaders
|
Fever
|
|
Macrophages are activated ? Along with PMN's(neutrophils) they are the key ? agents of nonspecific response to disease.
|
monocytes
phagocytic |
|
The plasma contains ?, a nonspecific group of chemicals that works on its own or with the 3rd line of defense to attack foreign cells
|
complement
|
|
What are the chief functions of inflammation?
A.? B.? C.? |
A. Mobilize & attract immune components to the site of injury
B. Set in motion mechanisms to repair tissue damage, localize & clear harmful substances. C. Destroy microbes and block further invasion |
|
When the inflammatory response is chronic, it has the potential to actually cause ?, ?, and ?
|
tissue damage
disease destruction |
|
The stages of inflammation in order are ?,?,?,?, and ?
|
injury
rubor & calor tumor/ loss of function dolor |
|
A small protein released by cells that has a specific effect on the interactions between cells, on communications between cells or on the behavior of cells is a ?
|
cytokine
|
|
extravisation is also known as ?
|
diapedesis
|
|
The term ? means clear fluid.
|
serous
|
|
The fluid that escapes when endothelial cells contract is called ? and this accumulation of fluid in the tissues is called ?
|
exudate
edema |
|
The tendency of cells to migrate in response to a specific chemical stimulus given off at a site of injury or infection is ?
|
chemotaxis
|
|
? are the first WBC's to the site of the infection.
|
Neutrophils
|
|
? clear pus, cellular debris, dead neutrophils, and damaged tissue
|
Macrophages
|
|
FUO stands for ?
|
Fever of Unknown Origin
|
|
The body temperature is normally maintained by a control center in the ? region of the brain and the temp is around ? Celsius or ? Farenheit.
|
hypothalamus
37C 98.6C |
|
Fever is initiated when a circulating substance called ? resets the hypothalmic thermostat to a higher temp.
|
pyrogen
|
|
Pyrogens are described as ? which means-coming from outside the body or ? (originating internally)
|
exogenous
endogenous |
|
? lymphocytes produce antibodies and ? lymphocytes kill intruders directly.
|
B
T |
|
? are general purpose phagocytes that react first in the inflammatory response and are a primary component of ?
|
Neutrophils
pus |
|
? are attracted to sites of parasitic infections and antigen-antibody reactions and only play a minor role in phagocytosis
|
Eosinophils
|
|
Special macrophages called ? migrate to a certain tissue and remain there during their life span.
|
hystiocytes
|
|
Lysosomes migrate to the scene of the phagosome and fuse with it to form a ?
|
phagolysosome
|
|
The benefits of fever are:
A.? B.? C.? |
A. inhibits multiplication of temp. sensitive microorganisms
B. starves bacteria of iron C. Increases metabolism |
|
The 3 main types of phagocytes are ?,?,?
|
neutrophils
macrophages monocytes |
|
What are the 3 types of interferon?
|
Interferon alpha, beta, gamma
|
|
? pyrogens are products of infectious agents such as viruses, bacteria, protozoans, and fungi.
|
Exogenous
|
|
One well characterized exogenous pyrogen is ? the lipopolysaccharide found in the cell walls of gram(-) bacteria.
|
endotoxin
|
|
? pyrogens are liberated by monocytes, neutrophils, and macrophages during the process of phagocytosis.
|
Endogenous
|