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12 Cards in this Set

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What is the brand name for Nitroglycerin

  • Nitrostat
  • Nitroquick
  • Nitrolingual
  • Nitro-Dur
  • Minitran
  • Nitro-Bid and others

What class of drug is NTG?

  • Vasodilator
  • nitrate

When was it first used:

Synthesized in 1846, nitroglycerin was first used to treat anginal attacks in 1879. It was granted FDA approval in 1938.

Indications for NTG?

Chest pain associated with ACS

Contraindications for NTG?

  • Hypotension (low blood pressure)
  • Increased intracanial pressure
  • Use of ED drugs in past 24 - 36 hours

Side Effects of NTG?

  • Can cause headaches immediately
  • Dizziness
  • Weakness
  • Tachycardia
  • Hypotension
  • Dry mouth
  • nausea
  • vomiting
  • Burning sensation on administration at site of administration

What is the dosage for NTG?

.4mg in cardiac cases


If chest pain continues and BP >= 90 another dose may be given every 5 mins to max of 3

How is NTG supplied?

Calibrated spray for delivering .4mg/spray


Small tablet containing .4mg/tablet

What are the actions of NTG?

Causes vascular smooth muscle relaxation, resulting in dilation of the coronary arteries, and systemic vasculature to increase myocardial perfusion and reduce myocardial workload.

How long does it take for NTG to be eliminated from the system?

Via SL is 1-8mins

How long does it take to reach the peak effect of the drug?

via SL 6-7 mins.

What are some of the drug interactions with NTG?

Alcohol caused severe hypotension and CV collapse may occur.




Calcium channel blockersmay cause symptomatic orthostatic hypotension