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34 Cards in this Set
- Front
- Back
epinephrine
|
beta > alpha
direct sympath |
|
norepi
|
alpha1 > alpha2 > beta1
direct sympath |
|
dopamine
|
D1 = D2 > beta > alpha
direct sympath (D1 = renal profusion) |
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dobutamine
|
beta1 > beta2, alpha
direct sympath |
|
ephedrine
|
stimulates epi & norepi release
indirect sympath |
|
cocaine
|
blocks reuptake of norepi, serotonin, dopamine
indirect sympath |
|
phenylephrine
|
alpha1 agonist
|
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midodrine
|
alpha1 agonist
|
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clonidine
|
alpha2 agonist
|
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isoproterenol
|
beta1 & beta2 agonist
|
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albuterol, pirbuterol, bitolterol
|
beta2 agonist
|
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terbutaline, ritodrine
|
beta2 agonist
|
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methyldopa
|
alpha2 agonist
|
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phenoxybenzamine, phentolamine
|
irreversible alpha antagonist
phentolamine is reversible & short acting |
|
prazosin, terazosin, doxazosin, tamsulosin, alfuzosin
|
selective alpha1 antagonist
|
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propranolol, nadolol, pinolol, timolol
|
beta1 & beta2 antagonist
|
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carvedilol, labetalol
|
alpha 1, beta1 & beta2 antagonist
|
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metoprolol, atenolol, esmolol, acebutolol, bisoprolol, betaxolol
|
selective beta1 antagonist
|
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hexamethonium, mecamylamine, trimethaphan
|
anti-nicotinics
|
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pilocarpine
|
M1, M2, M3 agonist
|
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carbachol
|
muscarinic & nicotinic agonist
|
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methacholine
|
M1, M2, M3 agonist
|
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bethanechol
|
M2, M3
does not cross BBB |
|
atropine, homatropine, tropicamide
|
M1, M2, M3 antagonist
atropine analogues (to dilate eyes) |
|
scopolamine
|
M1, M2, M3 antagonist
crosses BBB |
|
benztropine, biperiden, trihexyphenidyl
|
M1, M2, M3 antagonist
crosses BBB |
|
ipratroprium, tiotropium
|
muscarinic antagonist (inhaled)
|
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oxybutynin
|
M1, M2, M3 antagonist
other drugs for urinary incontinence: tolterodine, darifenacin, solifenacin, trospium |
|
propantheline
|
M3 muscarinic antagonist
|
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neostigmine, physostigmine
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reversibly inhibits AChE -> nicotinic & muscarinic stim
neostigmine does not cross BBB, physostigmine does |
|
edrophonium, pyridostigmine
|
reversible inhibit AChE -> nicotinic & muscarinic stim
|
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tacrine, donepezil, galantamine, rivastigmine
|
reversible inhibit AChE
|
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exhothiophate, isoflurophate
|
inhibit AChE -> nicotinic & muscarinic stim
|
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pralidoxime
|
reverse cholinesterase inhibitor binding to AChE
|