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6 Cards in this Set
- Front
- Back
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What is the mechanism of action of ACE inhibitors?
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stop angiotensin converting enzyme from converting angiotensin I to angiotensin II, blocking breakdown of bradykinin and decreasing the release of aldosterone
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What are the major effects of ACE inhibitor use?
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vasodilation (persistence of bradykinin and reduction of angiotensin II), diuresis (decreased aldosterone)
*decrease preload and afterload |
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What are the major adverse effects of ACE inhibitors?
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renal ischemia, coughing, angioedema
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What are ACE inhibitors used for?
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hypertension, in conjunction with others for heart failure
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What is a prodrug?
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compound that must be metabolized to its active form
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List two ACE inhibitors
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enalapril, benazepril
(most end in -pril or -prilat) |
