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10 Cards in this Set

  • Front
  • Back
What factors causes a right shift (high P50 = increased release of O2)
CADET faces right
high PCO2
Acidosis
Increased 2,3 DPG
Exercise/Hypoxemia
High temperature
Describe metabolism of porphyrin moiety of hemoglobin
Porphyrins-> biliverdin -> unconjugated bilirubin + albumin -> liver --> conjugated and excreted in bile --> colonic bacteria acts on bile pigments
What mediates platelet-platelet adhesion?
IIB/IIIA
What mediates platelet-collagen adhesion?
gp1B via vWF
Inhibitor of cytochrome P450
Inhibitors stop cyber kids from eating grapefruits
INH
Sulfonamides
Cimetidine
Ketoconazole/diflucan
Erythromycin
grapefruit juice
Mechanism of thrombolytics
activate plasminogen to plasmin
Management of hemophila A prior to surgery
cryo +/- Factor 8 to 100% preoperatively
30% postoperatively
P450 Inducers
Queen barb takes fenfen and refuses greasy carbs
Quinidine
Barbituates
Phenytoin
Rifampin
Griseofulvin
Carmazepine
St Johns Wort
Most common inherited hypercoagulability disorder?
Factor V Leiden
Formula for oxygen delivery
DO2 - CO x Hgb x SatO2