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11 Cards in this Set

  • Front
  • Back
What does the PaO2 reflect?
-the lung's ability to transfer O2
-diminishes slowly w/ age
What does hypoxemia occur secondary to?
-V/Q mismatch (most common)
-diffusion defect
-true hypoventilation
-breathing a reduced PaO2
What reflects the actual amount of O2 bound to Hb compared w/ total capacity?
SaO2 (clinically, >90% is considered adequate)
What does the PvO2 obtained from the pulmonary artery reflect?
tissue oxygenation (reflects balance between O2 delivery & O2 consumption)
What is a PvO2 <35 mmHg strong evidence of?
poor tissue oxygenation
What is a sudden drop in PvO2 most often caused by?
impaired circulation
What is the normal amount of CO bound to Hb?
0-1% (measured by co-oximetry)
In which direction will CO shift the oxyhemoglobin dissociation curve?
to the left (saturates Hb in place of O2 because of greater affinity)
How can you differentiate between causes of hypoxemia?
by adding PaO2 & PaCO2 while breathing 21% FIO2
-if total is between 110-130 mmHg, simple hypoventilation exists
-if total is <110 mmHg, then usually lung dysfunction (shunt, V/Q mismatch, diffusion defect
What are some situations in which a mixed acidosis can occur?
-COPD w/ hypoxia
-poisoning & drug OD
What are some instances where a mixed alkalosis could occur?
-critically ill patients in ICU
-ventilator induced alkalosis in the face of chronic hypercapnia