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29 Cards in this Set

  • Front
  • Back

Examples of proliferative cells in the body

Skin fibroblasts


SMooth muscle cells


Endothelial cells that line blood vessels


Epithelial cells of most internal organs

Pyrimidines

Which amino acid contains a sulfhydryl?

Cysteine


-SH

Inhibition of phosphofructokinase-1 by ATP is an example of what kind of inhibition?

Allosteric and Feedback inhibition

A transcription factor must contain what kind of signal?

Nuclear localization sequence

Ubiquitination

can affect proteins in many ways: it can signal for their degradation via the proteasome, alter their cellular location, affect their activity, and promote or prevent protein interactions.

Proteasome

Breaks down "garbage" protein


Completely degrades it


Different from protease which just hydrolyzes bond

If a protein becomes denatured and inserted into the inner membrane of mitochondria:

Choose answer: proton gradiant across inner membrane will dissipate


(not ETC will cease)

GAPDH - Glyceraldehyde 3 phophate dehydrogenase

Catalyzes glyceraldehyde 3 phosphate ---> 1,3 biphosphoglycerate

What is the best test to use to measure posttranslational modification of proteins (e.g. histone acetylation)

Western blot

Southern Blot

DNA

Northern blot

RNA

Vasopressin

Regulates fusion of aquaporins with apical membranes of collecting duct epithelial cells


ADH - increase H20 permeability

Apical membrane

Membrane of polarized cells - surface of membrane that faces inwards to the lumen

If bacteria enters the blood stream from the small intestine, which will be the first major organ that it will encounter

LIVER


-Blood from small intestine is transported first to liver, which regulates nutrient distribution and removes toxins form the blood

How to find percent increase or decrease of two numbers

Compared to the WT, a mutation resulting in the addition of a nucleotide (not effect stop codon) will result in:

Both will have the same amino terminal, but different primary carboxyl terminal sequence


(since another nucleotide is added)


N->C

Malate, Succinate, alpha-ketoglutarate

Produced during Krebs cycle

Centromere vs centrosome

Centromere: Part of chromosome that links sister chromatids


Centrosome: Cell organelle, center for microtubule organization

Kinetochore

Complex of proteins associated with centromere of chromosome during cell division, to which microtubules of spindle attach.

Complex of proteins associated with centromere of chromosome during cell division, to which microtubules of spindle attach.

Microtubules originate from ________ for cellular transport

Centrosome

T cell receptors from cytoxic T lymphocytes target:

CTL target viral antigens presented on the surface of the virus infected cells

Which regions are highly specific?

Which regions are highly specific?

Regions 1 and 3 are the variable portion of the light an heavy chain


antigen recognition

Where in the human male reproductive system do gametes become motile and capable of fertilization?

Sperm is produced in seminiferous tubules of testes, completes maturation and becomes motile in the epididymis

______ is required to break the bond between actin filament and myosin head

ATP


(why rigor mortis happens)

Type II Error

Miss, False negative

Type I Error

False alarm, False positive

Signal Detection Theory