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10 Cards in this Set
- Front
- Back
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What is the structure and function of erythrocytes ( RBC) |
Type of blood cell that has no nucleus and biconcave Contains haemoglobin which enables the transport of oxygen and carbon dioxide to and from the tissues |
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What is plasma |
Main component of blood that carries red blood cells Contains hormones, proteins, nutrients,mineral ions, dissolved gasses and waste Distributes heat |
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What is the role of haemoglobin |
Present in red blood cells Oxygen molecules bind to the haem groups and are carried around the body then released where they are needed in respiring tissues |
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How does partial pressure of oxygen affect oxygen haemoglobin binding? |
At high partial pressures, oxygen associates to form oxyhaemoglobin At low partial pressures, oxygen dissociates to form deoxyhaemoglobin |
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What is the chemical equation for the formation of oxyhaemoglobin |
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What do oxygen dissociation curves show? |
Saturation for haemoglobin with oxygen plotted against partial pressure of oxygen Curves fighter to the left shoe that the haemoglobin has a higher affinity for oxygen |
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Explain the shape of oxygen dissociation curves |
Sigmoidal shape (S-shaped) When first O molecuke binds, it changed the tertiary structure of haemoglobin do that it is easier for the second and third molecules to bind The third molecule changes the tertiary structure of haemoglobin so that it's more difficult for the fourth molecule to bind |
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How does fetal haemoglobin differ from adult haemoglobin |
Has a higher affinity for oxygen than adult haemoglobin due to the presence of 2 subunits that allow oxygen to bind more readily |
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Why is the higher affinity of fetal haemoglobin important |
Enables the fetus to obtain oxygen from the mothers blood |
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Compare the dissociation curves of adult and fetal haemoglobin |
Fetal haemoglobin curve to the left At the sane partial pressure, % oxygen saturation is greater for the fetus |
