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126 Cards in this Set
- Front
- Back
Acetylcholine
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Primary transmitter of the peripheral NS.
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Dopamine (DA)
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Catecholamine (tyrosine)/Biogenic amine
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Norepinephrine (NE)
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Catecholamine (tyrosine)/Biogenic amine
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Epinephrine (E)
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Catecholamine (tyrosine)/Biogenic amine
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Serotonin
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Biogenic amine
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Histamine
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Biogenic Amine
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Glycine (Gly)
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Amino acid Transmitter
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y-aminobutyric acid (GABA)
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Amino acid Transmitter
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Glutamate (Glu)
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Amino Acid Transmitter
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Aspartate (Asp)
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Amino Acid Transmitter
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Endorphin
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Opioid/Neuropeptide
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Enkephalin
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Opioid/Neuropeptide
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Dynorphin
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Opioid/Neuropeptide
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Nitric Oxide (NO)
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Gaseous Transmitter/ Mod
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Carbon Monoxide (CO)
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Gaseous Transmitter/ Mod
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Hydrogen Sulfide
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Gaseous Transmitter/ Mod (perhaps?)
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Tetrodotoxin
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Sodium Channel Blocker
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Saxitoxin
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Sodium Channel Blocker
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Mu-conotoxin
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Sodium Channel Blocker
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Lidocaine/procaine/tetracaine
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Use Dependent Sodium Blocker
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batrachotoxin
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Sodium Channel Promoter
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pyrethrins
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Sodium Channel Promoter
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brevetoxin
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Sodium Channel Promoter
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Botulinium Toxin
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Bacterial Toxin
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Tetanus Toxin
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Bacterial Toxin
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carbamylocholine/succinylcholine
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Agonist
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curare
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Antagonist
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physostigmine/neostigmine
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Inhibitor of Ach-esterase
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organophosphorous cmpds
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Inhibitor of Ach-esterase
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Acetylcholine
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Primary transmitter of the peripheral NS.Participates in several pathways in CNS degradation of paths occur in Alzheimer's disease
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Dopamine (DA)
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Catecholamine (tyrosine)/Biogenic amine Found in mid-brain and dienchephalon. Parkinsonism involved in it's degradation. Schizophrenia is linked to disorders in DA systems
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Norepinephrine (NE)
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Catecholamine (tyrosine)/Biogenic amine
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Epinephrine (E)
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Catecholamine (tyrosine)/Biogenic amine
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Serotonin
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Biogenic amine
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Histamine
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Biogenic Amine
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Glycine (Gly)
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Amino acid Transmitter
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y-aminobutyric acid (GABA)
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Amino acid Transmitter
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Glutamate (Glu)
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Amino Acid Transmitter
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Aspartate (Asp)
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Amino Acid Transmitter
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Endorphin
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Opioid/Neuropeptide
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Enkephalin
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Opioid/Neuropeptide
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Dynorphin
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Opioid/Neuropeptide
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Nitric Oxide (NO)
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Gaseous Transmitter/ Mod
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Carbon Monoxide (CO)
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Gaseous Transmitter/ Mod
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Hydrogen Sulfide
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Gaseous Transmitter/ Mod (perhaps?)
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Tetrodotoxin
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Sodium Channel Blocker
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Saxitoxin
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Sodium Channel Blocker
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Mu-conotoxin
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Sodium Channel Blocker
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Lidocaine/procaine/tetracaine
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Use Dependent Sodium Blocker
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batrachotoxin
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Sodium Channel Promoter
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pyrethrins
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Sodium Channel Promoter
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brevetoxin
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Sodium Channel Promoter
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Botulinium Toxin
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Bacterial Toxin
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Tetanus Toxin
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Bacterial Toxin
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carbamylocholine/succinylcholine
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Agonist
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curare
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Antagonist
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physostigmine/neostigmine
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Inhibitor of Ach-esterase
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|
organophosphorous cmpds
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Inhibitor of Ach-esterase
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Acetylcholine
|
Primary transmitter of the peripheral NS.
|
|
Dopamine (DA)
|
Catecholamine (tyrosine)/Biogenic amine
|
|
Norepinephrine (NE)
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Catecholamine (tyrosine)/Biogenic amine
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Influences sleep
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wakefulness
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Epinephrine (E)
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Catecholamine (tyrosine)/Biogenic amine
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Serotonin
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Biogenic amine
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Made from tryptophan (5-hydroxytryptamine
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5-HT)
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Implicated in onset of sleep
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mood
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Histamine
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Biogenic Amine
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Glycine (Gly)
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Amino acid Transmitter
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y-aminobutyric acid (GABA)
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Amino acid Transmitter
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Glutamate (Glu)
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Amino Acid Transmitter
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Aspartate (Asp)
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Amino Acid Transmitter
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Endorphin
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Opioid/Neuropeptide
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Enkephalin
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Opioid/Neuropeptide
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Dynorphin
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Opioid/Neuropeptide
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Nitric Oxide (NO)
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Gaseous Transmitter/ Mod
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Carbon Monoxide (CO)
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Gaseous Transmitter/ Mod
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Hydrogen Sulfide
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Gaseous Transmitter/ Mod (perhaps?)
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Tetrodotoxin
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Sodium Channel Blocker
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Prevents influx of sodium into cell
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preventing depolarization and subsequent action potentials and release of ACh
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Saxitoxin
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Sodium Channel Blocker
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Prevents influx of sodium into cell
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preventing depolarization and subsequent action potentials and release of ACh
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Mu-conotoxin
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Sodium Channel Blocker
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Prevents influx of sodium into cell in skeletal muscles
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preventing depolarization and subsequent action potentials
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Lidocaine/procaine/tetracaine
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Use Dependent Sodium Blocker
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batrachotoxin
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Sodium Channel Promoter
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Keeps sodium channel open for a much longer period of time
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leading to extensive depolarization
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pyrethrins
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Sodium Channel Promoter
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Keeps sodium channel open for a much longer period of time
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leading to extensive depolarization
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brevetoxin
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Sodium Channel Promoter
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Keeps sodium channel open for a much longer period of time
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leading to extensive depolarization
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Botulinium Toxin
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Bacterial Toxin
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Tetanus Toxin
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Bacterial Toxin
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carbamylocholine/succinylcholine
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Agonist
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Activates the Ach receptor to open for prolonged periods of time. Leads to prolonged depolarization (tremors). Eventually
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cells become desensitized because Na Channels are inactivated after prolonged depolarizations.. (relaxation)
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curare
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Antagonist
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Competitive inhibitor of Ach.. binding of the chemical prevents binding of Ach. Reduces the amplitude of EPP's
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leading to flaccid paralysis
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physostigmine/neostigmine
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Inhibitor of Ach-esterase
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|
organophosphorous cmpds
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Inhibitor of Ach-esterase
|
|
Acetylcholine
|
Primary transmitter of the peripheral NS.
|
|
degradation of paths occur in Alzheimer's disease;Dopamine (DA)
|
Catecholamine (tyrosine)/Biogenic amine
|
|
Schizophrenia is linked to disorders in DA systems;Norepinephrine (NE)
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Catecholamine (tyrosine)/Biogenic amine
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Influences sleep
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wakefulness
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unknown function in brain;Serotonin
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Biogenic amine
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Made from tryptophan (5-hydroxytryptamine
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5-HT)
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Implicated in onset of sleep
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mood
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Mediate arousal;Glycine (Gly)
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Amino acid Transmitter
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found in brainstem and spinal cord;y-aminobutyric acid (GABA)
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Amino acid Transmitter
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Deficit is implicated in Huntington's disease;Glutamate (Glu)
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Amino Acid Transmitter
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Can act as excitotoxin causing cell death if in excess;Aspartate (Asp)
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Amino Acid Transmitter
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Ubiquitous excitatory transmitter;Endorphin
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Opioid/Neuropeptide
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binds preferentially to u-receptors;Enkephalin
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Opioid/Neuropeptide
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binds to d-receptors;Dynorphin
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Opioid/Neuropeptide
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binds to K receptors;Nitric Oxide (NO)
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Gaseous Transmitter/ Mod
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Does not bind to post synaptic cell but diffuses into cell and directly interacts with secondary messengers systems;Carbon Monoxide (CO)
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Gaseous Transmitter/ Mod
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A major action is activation of guanylyl cyclase;Hydrogen Sulfide
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Gaseous Transmitter/ Mod (perhaps?);Tetrodotoxin
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Prevents influx of sodium into cell
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preventing depolarization and subsequent action potentials and release of ACh;Saxitoxin
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Prevents influx of sodium into cell
|
preventing depolarization and subsequent action potentials and release of ACh;Mu-conotoxin
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Prevents influx of sodium into cell in skeletal muscles
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preventing depolarization and subsequent action potentials;Lidocaine/procaine/tetracaine
|
|
Keeps sodium channel open for a much longer period of time
|
leading to extensive depolarization;pyrethrins
|
|
Keeps sodium channel open for a much longer period of time
|
leading to extensive depolarization;brevetoxin
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Keeps sodium channel open for a much longer period of time
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leading to extensive depolarization;Botulinium Toxin
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inhibits neurotransmitter release by cleaving proteins related to normal vesicle fusion and exocytosis;Tetanus Toxin
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Bacterial Toxin
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Inhibits neurotransmitter release in the inhibitory neurons of the spinal cord. This causes the inhibitory neurons to fail when trying to inhibit contraction in the alpha-motoneurons;carbamylocholine/succinylcholine
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Agonist
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Activates the Ach receptor to open for prolonged periods of time. Leads to prolonged depolarization (tremors). Eventually
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cells become desensitized because Na Channels are inactivated after prolonged depolarizations.. (relaxation);curare
|
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Competitive inhibitor of Ach.. binding of the chemical prevents binding of Ach. Reduces the amplitude of EPP's
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leading to flaccid paralysis;physostigmine/neostigmine
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prolongs duration and amplitude of EPP... leads to flaccid paralysis of musculature...... will slowly hydrolyze and lose effectiveness (reversible);organophosphorous cmpds
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Inhibitor of Ach-esterase
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