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72 Cards in this Set
- Front
- Back
Name this compound.
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Abilify (Aripiprazole)
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What is this compound?
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Fluphenazine.
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Name this compound.
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Haloperidol
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Name this compound.
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Olanzapine
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Name this compound.
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Quetiapine
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Name this compound.
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Risperidone.
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Name this compound.
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Thioxanthene.
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Name this compound.
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Thorazine.
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Name this compound.
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Trilafon.
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Name this compound.
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Ziprasidone
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Name this compound and how it works in treating Parkinson's.
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Amantadine (Symmetrel); DA releasing agent
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Name this compound and how it works in treating Parkinson's.
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Benzatropine; anticholinergic agent.
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Name this compound.
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Bromocriptine.
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Name this compound.
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Cabergoline.
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What are the products of this reaction?
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Name this compound and its mode of action.
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Entacapone; COMT inhibitor
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Where does homovanillic acid come from?
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Major metabolism product of dopamine.
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Name this compound.
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Ortho-quinone.
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Name this compound.
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Pergolide.
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Name this compound and its mode of action.
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Pramipexole; D2 agonist.
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Name this compound and its mode of action.
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Raagiline (Azilect); MAOb inhibitor.
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Name this compound.
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Ropinirole.
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Name this compound.
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Rotigotine.
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Name this compound.
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Semi-quinone.
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Name this compound.
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Clonazepam (Clonopin)
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Name this compound.
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Clorazepate
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Name this compound.
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GABA!
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Name this compound and why it's different than the other classes of benzodiazepines.
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Imidazolo; tricyclic
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Name this compound.
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Triazolo.
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Name this compound and its class.
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Zolpidem (Ambien); benzodiazepine-like compound.
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Explain what's going on in this diagram.
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4) Active peptides taken up/stored in vesicles.
5) Peptides released when presynaptic neuron fires. 6) Endogenous opioid peptides bind to postsynaptic opioid receptors. 7) Second messenger effect is via inhibitory G-protein, promoting adenylate cyclase inactivation and thus decrease in cAMP. 8) Exogenous opioids bind just like endogenous opioids 9) Opioid antagonists competitively inhibit endogenous opioid action 10) Enkephalins are inactivated via enkephalinases. |
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What is this compound and what is it's significance?
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This is the major product of morphine metabolism (3-glucuronide). It CANNOT cross BBB and is not very potent.
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What is this compound and what is it's significance?
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This is the minor product of morphine metabolism, 6-glucuronide. It CAN cross the BBB and is more potent than morphine.
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What is the product of codeine metabolism?
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Morphine!
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Name this compound.
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Etorphine.
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Name this compound.
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Heroin.
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Name this compound.
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Hydrocodone.
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Name this compound.
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Hydromorphone.
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Name this compound. What other compound is the bolded part of the molecule isosteric with?
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Morphine; Tyrosine
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Name this compound.
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Naloxone.
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Name this compound.
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Naltrexone.
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Name this compound.
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Oxycodone.
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Name this compound.
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Oxymorphone.
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Name this compound and why it's important.
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Thebaine; many semi-synthetic opioids are derived from it.
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What happens if the 6-OH is changed to a 6-keto?
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Decrease in activity.
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What happens if the 3-OH is changed to a 3-OMethyl?
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Decrease in activity.
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What happens if the NMethyl is changed to a N-Methyl-Methyl-Phenol?
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10x increase in activity.
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Name this compound and the class it belongs to.
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Alfentanil Hydrochloride; 4-analidopiperidines
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Name this compound and the class it belongs to.
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Demerol; phenylpiperidine derivatives
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Name this compound and the class it belongs to.
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Fentanyl citrate; 4-analidopiperidines.
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Name this compound and the class it belongs to.
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Methadone; diphenylheptanones
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Name the methadone bi-products.
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1) Normethadone
2) Inactive pyrrolidine 3) alpha-methadol (less active) 4) alpha-normethadol (active) 5) alpha-dinormethadol (active) |
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Name this compound and the class it belongs to.
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Propoxyphene; diphenylheptanones
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Name this compound and the class it belongs to.
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Ultiva (Remifentanil); 4-analidopiperidines
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Name this compound and the class it belongs to.
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Sufentanil Citrate; 4-analidopiperidines
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Name this compound.
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Talpentadol
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Name this compound.
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Tramadol.
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Name this compound.
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Buprenorphine.
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Name this compound.
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Butorphanol Tartrate
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Name this compound.
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Dezocine.
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Name this compound.
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Difenoxin HCL
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Name this compound.
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Diphenoxylate HCl.
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Name this compound.
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Loperamide HCL/Imodium
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Name this compound.
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Nalbuphine HCl (Nubain)
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Name this compound.
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Pentazocine.
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This drug (desloratidine) is produced after metabolism of which parent drug?
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Claritin or Loratidine
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Which class of drug is this a scaffold for?
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First generation H1 antagonists; Ethanolamines
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Name this compound.
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Histamine.
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Name this compound.
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Omeprazole.
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What class of drug does this drug belong to?
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First generation H1 antagonists; Ethylenediamines
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What class of drug does this belong to?
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First generation H1 antagonists; piperazines
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Name this compound.
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Terfenadine or Seldane
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