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22 Cards in this Set
- Front
- Back
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Qualitative alteration |
Inherited granulocytic alteration Acquired granulocytic alteration |
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Leukocyte count is dependent on |
Myeloid and lymphoid precursor Circulating granulocyte pool Marginal granulocyte pool Extravasation of cells from pb |
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Function of neutrophil |
Migration and diapedesis Opsonization and recognition Phagocytosis |
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Neutrophilia |
>6.0X10 9/l |
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Do not involve tissue damage |
Physiologic |
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In response to disease and usually tissue damage |
Pathologic |
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Neutropenia |
1.5x10 9/l |
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Mechanism of neutropenia |
Dec flow of neutrophil neutro Remove neutroAlter CGP/MGPCombine Alter CGP/MGP Combine |
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Myeloid hypoplesia |
Infantile genetic agranulo(kostmann),schwa humans diamond syndrome,fanconi anemia |
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Ineffective granulocytosis |
CHS Megaloblastic anemia Myeloproliferative disorders |
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Increased destruction in circulation |
Viral ,protozoal,drugs(phenylbutazone,amidopyrine) |
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Pseudoneutropenia |
Endotoxins Drugs-chloramphenicol |
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Above 0.35x10 9/L in automated instrument ,direct chamber count-0.5x10 9 |
Eosinophilia |
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Eosinophilia is seen in |
Allergic(asthma,rhinitis atopic conditions) Skin disorder-atopic derm,phempigus ,eczema Para Hyper eosinophilia(loeffler syn,cystic fibrosis,churg Strauss synd Blood -CML,AML,PA |
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Basophilia |
>0.2x10 9/L |
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Basophilia is seen in |
Allergy - urticaria,allergy,eryrhroderma Infection-chic pox small pox influenza Inflammatory disorder-ra,uc,collagen vascular disease Hema-CML Endocrine a diabetes,hypothyroid Myeloid metaplasia-poly vera |
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Monocytosis |
>1.0 X10 9/L(adult) >1.2x109/L(newborn) |
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Monocytopenia |
<0.2 X10 9/l |
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Lymphocytosis |
Infant >10.0 X109/L Adult>40.0X10 9/L |
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Lymphocytopenia |
Adult<1.5 X10 9/L Children<3.0 X 10 9/l |
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Lymphocytosis seen in |
B strep,pertuss,brucellosis,tb,typhoid fever,syphil,viral cmv |
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Lymphocytopenia |
Infection HIV Drugs-acth,chemo Physical agent-x ray |
