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5 Cards in this Set
- Front
- Back
Alcoholic Liver Disease:
Common malady in Western society. Three major phases: ___ |
1. Fatty liver [one binge drinking session, these will reverse]
2. Alcoholic hepatitis 3. Cirrhosis |
|
Fatty Liver:
-What stage of what disease? All chronic alcoholics accumulate fat within their liver cells. -Liver can attain ___ times normal weight. -___hepatocytes are first affected. -With cessation of drinking, it is ___ and has few functional consequences. e.g. after one night of binge drinking |
-1st stage of alcoholic liver disease
-three -Centrilobular -reversible |
|
Alcoholic Hepatitis:
-What stage of what disease? More severe than fatty liver. Alcoholic hepatitis presents a significant mortality. It is an inflammatory, necrotizing disease. -There is a ___ inflammatory response and necrosis of hepatocytes in the ___ |
-2nd stage of alcoholic liver disease
-neutrophilic -central zone (Zone 3, around the central vein). |
|
Cirrhosis:
-What stage of what disease? -A scarring of the liver which can lead to ___ and/or ___ -Histologically, ___ form around hepatocellular nodules. The normal structure and consequent function of the liver is disturbed. Cirrhosis of the liver can have causes other than alcoholism. |
-3rd stage of alcoholic liver disease
-portal hypertension -liver failure -fibrous septa s. 26 |
|
Cardiac Cirrhosis:
Heart failure can cause liver damage that can lead to cirrhosis. Hepatocytes in zone 3 that normally receive the least oxygen and nutrients, are very susceptible to ___ & ___ No noticeable changes are seen in zones ___. |
-ischemia and hypoxia
1 and 2 s. 27 |