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10 Cards in this Set
- Front
- Back
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Which special properties does diclofenac have over other NSAIDs? |
It accumulates in synovial fluid, possibly making it more useful in treating joint pain. It also has higher cardiovascular risk. |
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Which special properties does indomethacin have over other NSAIDs? |
It inhibits phagocytosis of urate crystals, possibly making it more useful in treating gout. |
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Which NSAIDs has less cardiovascular risk than other NSAIDs? |
Naproxen, ibuprofen |
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Name some COX2-preferential NSAIDs |
Celecoxib, paracetamol, meloxicam |
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Name some COX2-specific NSAIDs |
Parecoxib, etoricoxib |
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In what cases are COX2-selective NSAIDs preferred over non-selective NSAIDs? |
- Peptic ulcer - Platelet disorders - Aspirin asthma - Familial adenomatius polyposis |
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Which NSAID has the highest cardiovascular risk? |
Diclofenac |
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What are the contraindications for coxibs? |
Sulpha allergy |
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What are the side effects of COX2-selective NSAIDs? |
Decreased renal function Cardiovascular side effects |
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Which side effects do COX2-selective NSAIDs lack compared to non-selective ones? |
COX2-selective NSAIDs have: - No antiplatelet effect - Minimal GI side effects - No aspirin asthma |
