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26 Cards in this Set
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cyclophosphamide
monitor blood count with cytotoxics wbc platelets monitor renal and liver increase fluids monitor I&O |
(Cytotoxin) treatment for Lupus
a. especially when lung and kidneys are involved; mentrual cycle and causes hair loss; take with lots of water and use sunscreen |
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mycophenolate
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*Cellcept* treatment for Lupus usually prescribed after renal and cardiac transplants.
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Azathioprine
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(Imuran) (Immunosuppresent) treatment for Lupus and transplants. metabolized quickly by the liver. been in use over 25 years. Inhibits tcell and antibody. May be given to patients with renal failure because metabolized so quickly.
ae: hepatoxicity, pancreatitis, |
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etanercept
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?
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anakinra
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x
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amitryptylline
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fibromyalgia
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Treatment for gout
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116. NSAIDS (indocin) and/or cholchicine
i. allopurinol (Zyloprim) or febuxostat (Uloric) 1. NSAIDS |
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Enfuvirtide (HIV)
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(Fuzeon) infusion inhibitor
Helps to decrase the amount of virus in the body and limit its spread. |
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Zidovudine (Retrovir) (HIV)
didanosine (videx) (used with zidovudine) stavudine (d4t, Zerit)(intolerent to AZT) lamivudine (3-tc, epivir) firstline with azt abacavir (Ziagin) can cause hypersensitivity zidovudine +lamivudine (combivir) used when there is HIV resistance to zidovudine. |
(Retrovir) (NRTIS) Necleoside reverse transcriptase inhibitors.
Interfere with the viruss ability to convert RNA into DNA |
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Delevirdine (Rescriptor) (HIV)
efavirenz (Sustiva) nevirapine (viramune) liver toxicity cross resistance to NRTIs |
(Rescriptor) NNRTIS
Inhibit viral replication in cells enzyme level. |
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efavirenz (HIV)
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(Sustiva) NNRTIS
Inhibit viral replication in cells |
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Amprenavir
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(Agenerase) Protease Inhibitors
Inhibit an enzyme needed for the virus to replicate |
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nelfinavir
lopinavir/ritonavir (kaletra) 1st line combo when strain is resistant to other PIs. |
(viracept) Protease Inhibitors
Inhibit an enzyme needed for the virus to replicate |
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saquiavir
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(Invarase) Protease Inhibitors
Inhibit an enzyme needed for the virus to replicate |
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indinavir
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(Crixivan) Protease Inhibitors
Inhibit an enzyme needed for the virus to replicate |
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interleukin
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(Interferon) antineoplastic medication
Immunostimulant that enhances the immune response and reduces the production of cancer cells (used commonly with Kaposi's sarcoma) |
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Colchicine
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(Novocolchine) antigout agent;
Therapeutic:antigout should be taken with food. |
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TNF
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cachexin, or cachectin
is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. |
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(Chlor-Trimeton)
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44. Benedryl, Chlorpheniramine
1st generation anti-histamine |
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2nd generation anti-histamine
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45. Zyrtec/cetirizine; Claritin/loratidine; Allegra/fexofenidine
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epinephrine
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adrenergic agonist (sympathomimetic)
vasoconstricting and bronchodilating effects 1:10,000; code carts |
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Plaquenil/hydroxychloroquine (SLE)
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(antimalarial)
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cyclosporine
tacrolimus sirolimus |
(Sandimmute)
(Prograf) (Rapamune) given with glucocorticoid Avoid grapefruit juices. monitor bun and creatinine monitor blood pressure T cell suppressor Inhibits Tcell function and normal cell mediated immune responses. Blood levels monitored closely nephro and hepa toxic. SE: hypertension CNS symptoms flushing tingling of the extremities, confusion, visual distrubances, and seizures or coma. |
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basiliximad
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(Simulect) monoclonal antibody
used when steroid resistant |
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daclizumab
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(Zenaprex) combo of mouse and human antibodies and cause fewer side effects.
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antithymocyte globulin (ATG)
antilymphocyte globulin (ALG) |
perform skin test for sensitivity to horse serum prior to initial dose.
have epinephrine and hydrocortizone on hand administor over 4 to 6 hours. |
