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54 Cards in this Set

  • Front
  • Back
Malaria:
Vector

p. falciparum vs p. ovale and p. vivax:
Latency
Difference in Mortality (why)
Defining Characteristics of Each

Diagnostics
Malaria:

Vector: female anopheles mosquito

p falciparum: NO LATENCY period, high mortality because all RBC's invaded, and exhibit seuquestration (via knobs) and immune evasion

p. ovale: latency

p. vivax: splenic rupture, latency

Dx: Smear every 6-12 hours for 48 hours
Leishmaniasis:
Vector

Cutaneous, Mucocutaneous, Visceral:
Strains
Geographic Distribution
Reservoirs (if applicable)
Symptoms

Diagnostics
Leishmaniasis:
Female phlebotomine SANDFLY

Cutaneous:
L tropic, L. Brazil; Brazil, M. East

(AKA KALA-AZAR)
Dogs = Reservoir

Mucocutaneous: L. Brazil, BRAZIL ONLY
Dx: PCR! Very few parasites in ulcer

Vicersal: L. Donovani; Brazil, M East
Syx: Chronic fever, SPLENOMEGALY, anemia, leukopenia, elevated gabba globulins
Dx: Aspirate Spleen
Trypanosomes:
African vs American Strains:
Vector
Symptoms
Diagnostics
African = African Sleeping Sickness
Vector = Tsetse Fly

East (SEVERE): T. Rhodesiense (Zoonosis)
West (Slow): T. Gambiense

Syx: Indurated, painful swelling, CNS involvement (crosses BBB; drowsiness-->stupor-->coma-->death)

INTERMITTENT FEVERS (due to variable surface glycoprots and immune system constantly mounting new responses)

Dx: Blood smear

American = T. Cruzi = CHAGAS DZ

Vector: kissing bug (reduviid); eats and poops near mucous membrane

Syx: MEGACOLON (affects Meisner's and Auerbach's plexi)
DILATED CARDIOMYOPATHY

Dx: Smear
Enatmoeba:
Location
Non-Invasive vs Invasive vs Cutaneous
Diagnostics
Entamoeba: COLON

Non-invasive: colony in intestinal mucosa, asyx encystation, NON-DYSENTERIC

Invasive: Mucosal Necrosis, DYSENTERIC

Cutaneous: Intestinal/hepatic fistula results in perianal/urogenital ulcer

Dx: 3x stool exams
If extraintestinal: abscess (amoeboma) aspirate
Dysentery
blood +/- mucus in stool 2-3x/day
Giardia:
Route of Transmission
Reservoir
Symptoms
Giardia:
fecal-oral
beaver reservoir
Syx: EXPLOSIVE, FOUL-SMELLING DIARRHEA (no blood or mucus)
Asciarisis
Worm Type
Transmission
Reservoir
Symptoms
Giant luminal nematode (ROUNDWORM)

Oral-fecal, doughnut at least x1

Dog and Cat Reservoirs (produce visceral larva migrans)

Hypoproteinemia-->ASCITES
Penumonia, Bowel Obstruction
Hookworm:
Worm Type
Transmission
Reservoirs
Symptoms
Hookworm:
Nematode
Dog and Cat produce cutaneous larva migrans which penetrate skin

One pass through doughnut

Syx: Fe-deficient anemia
Cachexia-->failure to thrive

(6 ft outhouse)
Strongyloidiasis:
Worm Type
Transmission
Symptoms
Nematode

Free-living in soil and penetrate skin, pass doughnut

Syx: Pneumonitis, secondary bacteremia (poop while migrate), malabsorption + diarrhea (chronic)

Dx: String test, feces O+P
Pinworm:
Worm Type
Symptoms
Nematode

Scratchy butt

No dz

Tape Test
Whipworm:
Worm Type
Symptoms
Nematode

Rectal prolapse!
Lymphatic Filariasis:
Worm Type
Method of Transmission
Symptoms
Tissue Nematode (Roundworm)

Mosquito deposits larvae, mature in LV's

Syx: Elephantiasis, MEGAscrotum

Wash your feet!
Loa Loa:
Worm Type
Method of Transmission
Symptoms
Tissue Nematode

Deer flies infect, microfils release with diurnal periodicity

Syx: Eye worms (cross conjunctiva) without blindness
Calabar Swelling (over bony prominences when worm dies)
Dramatic EOSINOPEHLIA
Onchocerciasis:
Worm Type
Method of Transmission
Symptoms
Tissue Nematode (ROUNDWORM)

Black fly deposits larvae
Live in nodules under skin

Syx: PRURITIS (itch) leads to secondary infection, scarring, loss of pigementation
RIVER BLINDNESS
(occurs near fast moving water)
Elephantiasis of groin
Trichinella Spiralis:
Worm Type
Method of Transmission
Symptoms
Tissue Nematode

Undercooked pork/bear-->larvae-->migrate to striated muscle

Dz: Eosin, myalgia, cardiomyop, CNS disturb
Cysticercosis:
Worm Type
Method of Transmission
Symptoms
TISSUE CESTODE: Flat/Tapeworm

Ingest T. solium eggs (poop)-->desimminate

NOT FROM RAW MEAT

Dz: Seizures, paralysis, hcephalus

Dx: CT, MRI
Hydatid Disease:
Worm Type
Method of Transmission
Symptoms
Tissue Cestodes (SEGMENTED flatworm/tapeworm)

E. multilocularis: multiple uncapsulated, diff to resect
E. granulosus: single, capsulated, resectable

Dog tapeworms with sheep IM's; humans ingest eggs from dog poop

DON'T ASPIRATE
Schistosomiasis:
Worm Type
Method of Transmission
Symptoms
Trematode (NON-SEGMENTED flat/tapeworm)

Snails shed cercaria-->penetrate skin-->migrate through doughnut

Syx: KATAYAMA FEVER, LAD (acute)
Hepatosplenomeg, Portal HTN, Urothelial Ca (Chronic)